Upregulation of TREM2 Ameliorates Neuropathology and Rescues Spatial Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease

Neuropsychopharmacology ◽

10.1038/npp.2014.164 ◽

2014 ◽

Vol 39 (13) ◽

pp. 2949-2962 ◽

Author(s):

Teng Jiang ◽

Lan Tan ◽

Xi-Chen Zhu ◽

Qiao-Quan Zhang ◽

Lei Cao ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: Studies in a transgenic mouse model of Alzheimer’s disease

Brain Behavior and Immunity ◽

10.1016/j.bbi.2019.08.194 ◽

2019 ◽

Vol 82 ◽

pp. 264-278 ◽

Author(s):

Hui-Qin Li ◽

Siu-Po Ip ◽

Qiu-Ju Yuan ◽

Guo-Qing Zheng ◽

Karl K.W. Tsim ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Tau Hyperphosphorylation ◽

Amyloid Pathology ◽

Model Of Alzheimer’S Disease

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Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD)

Behavioural Brain Research ◽

10.1016/j.bbr.2015.04.028 ◽

2015 ◽

Vol 289 ◽

pp. 69-77 ◽

Author(s):

Akira Nakajima ◽

Yuki Aoyama ◽

Eun-Joo Shin ◽

Yunsung Nam ◽

Hyoung-Chun Kim ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease ◽

Triple Transgenic Mouse

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WBQ5187, a Multitarget Directed Agent, Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease and Modulates Cerebral β-Amyloid, Gliosis, cAMP Levels, and Neurodegeneration

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.9b00409 ◽

2019 ◽

Vol 10 (12) ◽

pp. 4787-4799

Author(s):

Zhiren Wang ◽

Mengru Cao ◽

Hongling Xiang ◽

Wei Wang ◽

Xing Feng ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease ◽

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The role of neuroinflammation and amyloid in cognitive impairment in an APP/PS1 transgenic mouse model of Alzheimer's disease

CNS Neuroscience & Therapeutics ◽

10.1111/cns.12677 ◽

2017 ◽

Vol 23 (4) ◽

pp. 310-320 ◽

Author(s):

Shenghua Zhu ◽

Junhui Wang ◽

Yanbo Zhang ◽

Jue He ◽

Jiming Kong ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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Subcutaneous Sustained-Release of Poly-Arginine Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease

Advances in Alzheimer s Disease ◽

10.4236/aad.2018.74011 ◽

2018 ◽

Vol 07 (04) ◽

pp. 153-182 ◽

Author(s):

Gennadiy Fonar ◽

Baruh Polis ◽

Tomer Meirson ◽

Alexander Maltsev ◽

Abraham O. Samson

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Sustained Release ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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Immunological alteration & toxic molecular inductions leading to cognitive impairment & neurotoxicity in transgenic mouse model of Alzheimer's disease

Life Sciences ◽

10.1016/j.lfs.2017.03.004 ◽

2017 ◽

Vol 177 ◽

pp. 49-59 ◽

Author(s):

Manuj Ahuja ◽

Manal Buabeid ◽

Engy Abdel-Rahman ◽

Mohammed Majrashi ◽

Kodeeswaran Parameshwaran ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Model Of Alzheimer’S Disease

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P3-396: NK-4, a photosensitizing cyanine dye, prevented beta-amyloid-induced cognitive impairment in a transgenic mouse model of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2010.05.1938 ◽

2010 ◽

Vol 6 ◽

pp. S568-S568

Author(s):

Hitomi Ohta ◽

Kenji Akita ◽

Shigeyuki Arai ◽

Tsunetaka Ohta ◽

Toshio Kawata ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Beta Amyloid ◽

Transgenic Mouse Model ◽

Cyanine Dye ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Preserved fronto-striatal plasticity and enhanced procedural learning in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020559.235469 ◽

2004 ◽

Author(s):

Karl-Peter Giese

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Procedural Learning ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5594956.5560054 ◽

2010 ◽

Author(s):

Riqiang Yan

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Beta Amyloid ◽

Transgenic Mouse Model ◽

Amyloid Deposition ◽

Gamma Secretase ◽

Model Of Alzheimer’S Disease

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High‐Fat Diet Modulates Hepatic Amyloid β and Cerebrosterol Metabolism in the Triple Transgenic Mouse Model of Alzheimer’s Disease

Hepatology Communications ◽

10.1002/hep4.1609 ◽

2020 ◽

Author(s):

Cristina R. Bosoi ◽

Milène Vandal ◽

Marine Tournissac ◽

Manon Leclerc ◽

Hortense Fanet ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

High Fat Diet ◽

Transgenic Mouse Model ◽

High Fat ◽

Model Of Alzheimer’S Disease ◽

Triple Transgenic Mouse

Download Full-text