WBQ5187, a Multitarget Directed Agent, Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer’s Disease and Modulates Cerebral β-Amyloid, Gliosis, cAMP Levels, and Neurodegeneration

Β Amyloid ◽

Camp Levels

Icariin Decreases the Expression of APP and BACE-1 and Reduces the β-amyloid Burden in an APP Transgenic Mouse Model of Alzheimer's Disease

International Journal of Biological Sciences ◽

10.7150/ijbs.6232 ◽

2014 ◽

Vol 10 (2) ◽

pp. 181-191 ◽

Cited By ~ 39

Author(s):

Lan Zhang ◽

Cong Shen ◽

Jin Chu ◽

Ruyi Zhang ◽

Yali Li ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Amyloid Burden ◽

Β Amyloid ◽

Bace 1

Isorhynchophylline ameliorates cognitive impairment via modulating amyloid pathology, tau hyperphosphorylation and neuroinflammation: Studies in a transgenic mouse model of Alzheimer’s disease

Brain Behavior and Immunity ◽

10.1016/j.bbi.2019.08.194 ◽

2019 ◽

Vol 82 ◽

pp. 264-278 ◽

Cited By ~ 6

Author(s):

Hui-Qin Li ◽

Siu-Po Ip ◽

Qiu-Ju Yuan ◽

Guo-Qing Zheng ◽

Karl K.W. Tsim ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Tau Hyperphosphorylation ◽

Amyloid Pathology ◽

Model Of Alzheimer’S Disease

Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD)

Behavioural Brain Research ◽

10.1016/j.bbr.2015.04.028 ◽

2015 ◽

Vol 289 ◽

pp. 69-77 ◽

Cited By ~ 53

Author(s):

Akira Nakajima ◽

Yuki Aoyama ◽

Eun-Joo Shin ◽

Yunsung Nam ◽

Hyoung-Chun Kim ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Triple Transgenic Mouse

Fibrillar β-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer’s disease

Neuroscience ◽

10.1016/s0306-4522(01)00115-4 ◽

2001 ◽

Vol 104 (3) ◽

pp. 609-613 ◽

Cited By ~ 85

Author(s):

Y Matsuoka ◽

M Picciano ◽

J La Francois ◽

K Duff

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Oxidative Damage ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Apolipoprotein E Dose-Dependent Modulation of β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

Journal of Molecular Neuroscience ◽

10.1385/jmn:23:3:255 ◽

2004 ◽

Vol 23 (3) ◽

pp. 255-262 ◽

Cited By ~ 30

Author(s):

Ronald B. DeMattos

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Apolipoprotein E ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Amyloid Deposition ◽

Β Amyloid ◽

Dose Dependent

Statistical aspects of quantitative image analysis of β-amyloid in the APPV717F transgenic mouse model of Alzheimer's disease

Journal of Neuroscience Methods ◽

10.1016/s0165-0270(01)00381-8 ◽

2001 ◽

Vol 108 (2) ◽

pp. 145-152 ◽

Cited By ~ 12

Author(s):

Cindy E. Fishman ◽

David J. Cummins ◽

Kelly R. Bales ◽

Cynthia A. DeLong ◽

Michail A. Esterman ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Image Analysis ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Quantitative Image Analysis ◽

Quantitative Image ◽

High tryptophan diet reduces CA1 intraneuronal β-amyloid in the triple transgenic mouse model of Alzheimer’s disease

Aging Cell ◽

10.1111/j.1474-9726.2012.00845.x ◽

2012 ◽

Vol 11 (5) ◽

pp. 810-822 ◽

Cited By ~ 30

Author(s):

Harun N. Noristani ◽

Alexei Verkhratsky ◽

José J. Rodríguez

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Β Amyloid ◽

Triple Transgenic Mouse

β-Amyloid Plaques Induce Neuritic Dystrophy of Nitric Oxide-Producing Neurons in a Transgenic Mouse Model of Alzheimer's Disease

Experimental Neurology ◽

10.1006/exnr.2000.7598 ◽

2001 ◽

Vol 168 (2) ◽

pp. 203-212 ◽

Cited By ~ 20

Author(s):

Joseph Quinn ◽

Forrest Davis ◽

William R. Woodward ◽

Felix Eckenstein

Keyword(s):

Nitric Oxide ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Amyloid Plaques ◽

Transgenic Mouse Model ◽

Neuritic Dystrophy ◽

A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

Neurobiology of Disease ◽

10.1006/nbdi.2001.0422 ◽

2001 ◽

Vol 8 (5) ◽

pp. 890-899 ◽

Cited By ~ 333

Author(s):

L.M. Refolo ◽

M.A. Pappolla ◽

J. LaFrancois ◽

B. Malester ◽

S.D. Schmidt ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Cholesterol Lowering ◽

Amyloid Pathology ◽

Β Amyloid ◽

Lowering Drug

Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve cognition in a transgenic mouse model of Alzheimer’s disease 24 h after single treatment

Translational Psychiatry ◽

10.1038/tp.2012.151 ◽

2013 ◽

Vol 3 (3) ◽

pp. e236-e236 ◽

Cited By ~ 15

Author(s):

D Mengel ◽

S Röskam ◽

F Neff ◽

K Balakrishnan ◽

O Deuster ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Single Treatment ◽

Naturally Occurring ◽

Amyloid Metabolism ◽