Clinical and biological aspects of myeloid leukemia in Down syndrome

Leukemia ◽  
2021 ◽  
Author(s):  
Austin C. Boucher ◽  
Kenneth J. Caldwell ◽  
John D. Crispino ◽  
Jamie E. Flerlage
Keyword(s):  
Down Syndrome ◽  
Myeloid Leukemia ◽  
Biological Aspects

Cooperativity between miR-125b and Gata1 s in the pathogenesis of Down syndrome-associated myeloid leukemia

2019 ◽  
Author(s):  
O Alejo-Valle ◽  
M Labuhn ◽  
E Emmrich ◽  
M Ng ◽  
D Heckl ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Myeloid Leukemia

Clinical and biological aspects of philadelphia-Negative/BCR-Negative chronic myeloid leukemia

1997 ◽  
Vol 25 (3-4) ◽  
pp. 225-232 ◽  
Author(s):  
Régis Costello ◽  
Danielle Sainty ◽  
Marina Lafage-Pochitaloff ◽  
Jean Gabert
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Biological Aspects

scholarly journals Minimally differentiated acute myeloid leukemia with ring/marker derived from chromosome 7 in a child with Down syndrome

2019 ◽  
Vol 41 (1) ◽  
pp. 84-87
Author(s):  
Maria Luiza Rocha da Rosa Borges ◽  
Eliane Maria Soares-Ventura ◽  
Thomas Liehr ◽  
Terezinha de Jesus Marques-Salles
Keyword(s):  
Acute Myeloid Leukemia ◽  
Down Syndrome ◽  
Myeloid Leukemia ◽  
Chromosome 7 ◽  
Acute Myeloid

scholarly journals Infections in children with down syndrome and acute myeloid leukemia: a report from the Canadian infections in AML research group

2013 ◽  
Vol 8 (1) ◽  
pp. 47 ◽  
Author(s):  
Thai Tran ◽  
David Mitchell ◽  
David Dix ◽  
Sonia Cellot ◽  
Marie-Chantal Ethier ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Down Syndrome ◽  
Research Group ◽  
Myeloid Leukemia ◽  
Children With Down Syndrome ◽  
Acute Myeloid

scholarly journals Retrospective Analysis of the Treatment Outcome in Myeloid Leukemia of Down Syndrome in Polish Pediatric Leukemia and Lymphoma Study Group From 2005 to 2019

2020 ◽  
Vol 8 ◽  
Author(s):  
Malgorzata Czogala ◽  
Katarzyna Pawinska-Wasikowska ◽  
Teofila Ksiazek ◽  
Barbara Sikorska-Fic ◽  
Michal Matysiak ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Treatment Outcome ◽  
Retrospective Analysis ◽  
Myeloid Leukemia ◽  
Study Group ◽  
Pediatric Leukemia ◽  
Lymphoma Study Group

scholarly journals Therapy reduction in patients with Down syndrome and myeloid leukemia: the international ML-DS 2006 trial

Blood ◽  
2017 ◽  
Vol 129 (25) ◽  
pp. 3314-3321 ◽  
Author(s):  
Madita Uffmann ◽  
Mareike Rasche ◽  
Martin Zimmermann ◽  
Christine von Neuhoff ◽  
Ursula Creutzig ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Prognostic Factors ◽  
Treatment Response ◽  
Early Treatment ◽  
Myeloid Leukemia ◽  
Chromosome 8 ◽  
Historical Control ◽  
Early Treatment Response ◽  
Key Points ◽  
Therapy Reduction

Key Points Reducing therapy intensity in the ML-DS 2006 trial did not impair the excellent prognosis in ML-DS compared with the historical control. Early treatment response and gain of chromosome 8 are independent prognostic factors.

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