Short- and Long-term Risks of Highly Active Antiretroviral Treatment with Incident Opportunistic Infections among People Living with HIV/AIDS

HIV/AIDS disease is a health problem in indonesia. The problem cause of the number of morbility and mortality that still hight. It is cause of long term infection, adherance consuming the drungs and opportunistic that can deastroy the imun system of People Living With HIV/AIDS (PLHIV). The purpose of this research is to identify the factors related to the people living with PLHIV in Achmad Muchtar Hospital Bukittinggi2016.This research was conducted by a retrospective cohort design approach, doing research of the death of people who living with HIV by observing the patient’s medical record from 2014-2015. The research of study were 215 patient’s who is criteria inclusion. Analysis data using test chi-square. who became the independent variable is long infection, adherance comsuming the Anti Retroviral (ARV) , and opportunistic infection and dependent variable that survive the HIV people life.The research showed that among 215 patients with the number of deaths 39 people ( 18,% ), stages 3 and 4 (>5 th) is 89 people ( 41.4% ), not adherence is 77 people ( 35.8% ), and who suffered an opportunistic infection were 61 people (28.4% ). The statistical test relationships survival of people living with HIV with long-term infection obtained p value = 0,000 and RR = 0,019 ( confidence interfal 95 % with alpha = 0.05 ), adherance comsuming the ARV obtained p value = 0,000 and RR = 0,494 ( confidence interfal 95 % with alpha = 0.05 ), infection opportunistic obtained p value = 0,000 and RR = 0,361 ( confidence interfal 95 % with αlpha = 0.05 ).From these findings, it can be concluded that the long-term infection, adherence ARV and opportunistic infections associated with survival of people living with HIV. Of the three variables obtained interrelated and value the highest association is long-term infection.

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The Time Gap between Repeated Re-Happening Opportunistic Infections among People Living with HIV/AIDS Commencing Antiretroviral Treatment

Clinical Medicine Research ◽

10.11648/j.cmr.20150401.13 ◽

2015 ◽

Vol 4 (1) ◽

pp. 11

Author(s):

Habtamu Mellie Bizuayehu

Keyword(s):

Antiretroviral Treatment ◽

Opportunistic Infections ◽

People Living With Hiv ◽

Time Gap ◽

Living With Hiv ◽

Hiv Aids

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Prevalence of Neurocognitive Impairment and Associated Factors Among People Living with HIV on Highly Active Antiretroviral Treatment, Ethiopia

HIV/AIDS - Research and Palliative Care ◽

10.2147/hiv.s298141 ◽

2021 ◽

Vol Volume 13 ◽

pp. 425-433

Author(s):

Abate Dargie Wubetu ◽

Kokebie Kefelegn Asefa ◽

Birhan Gebresillassie Gebregiorgis

Keyword(s):

Associated Factors ◽

Antiretroviral Treatment ◽

Neurocognitive Impairment ◽

People Living With Hiv ◽

Highly Active ◽

Highly Active Antiretroviral Treatment ◽

Living With Hiv

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Supporting Adherence to Highly Active Antiretroviral Therapy and Protected Sex Among People Living with HIV/AIDS: The Role of Patient–Provider Communication in Rio De Janeiro, Brazil

AIDS Patient Care and STDs ◽

10.1089/apc.2006.20.637 ◽

2006 ◽

Vol 20 (9) ◽

pp. 637-648 ◽

Cited By ~ 19

Author(s):

Jessica Fehringer ◽

Francisco I. Bastos ◽

Elize Massard ◽

Leonardo Maia ◽

J.H. Pilotto ◽

...

Keyword(s):

Antiretroviral Therapy ◽

Highly Active Antiretroviral Therapy ◽

Rio De Janeiro ◽

People Living With Hiv ◽

Provider Communication ◽

Highly Active ◽

Patient Provider Communication ◽

Living With Hiv ◽

Hiv Aids

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Rates and Predictors of Consistent Condom-use by People Living with HIV/AIDS on Antiretroviral Treatment in Uganda

Journal of Health Population and Nutrition ◽

10.3329/jhpn.v30i3.12290 ◽

2012 ◽

Vol 30 (3) ◽

Cited By ~ 14

Author(s):

Natal Ayiga

Keyword(s):

Condom Use ◽

Antiretroviral Treatment ◽

Consistent Condom ◽

People Living With Hiv ◽

Consistent Condom Use ◽

Living With Hiv ◽

Hiv Aids

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The THE SPECTRUM OF OPPORTUNISTIC INFECTIONS AND ASSOCIATED FACTORS AMONG PEOPLE LIVING WITH HIV/AIDS ON HIGHLY ACTIVE ANTI-RETROVIRAL THERAPY AT MERPATI CLINIC, BALI, INDONESIA: A RETROSPECTIVE STUDY

International Journal of Pharmacy and Pharmaceutical Sciences ◽

10.22159/ijpps.2020v12i6.37682 ◽

2020 ◽

pp. 68-71

Author(s):

NOVIANA JOENPUTRI ◽

KETUT SURYANA

Keyword(s):

Retrospective Study ◽

Marital Status ◽

Cell Count ◽

Associated Factors ◽

Opportunistic Infections ◽

People Living With Hiv ◽

Cd4 Cell Count ◽

Highly Active ◽

Living With Hiv ◽

Cd4 Cell

Objective: Infections contributed to higher morbidity and mortality in people living with HIV/AIDS (PLWHA) in both developed and developing countries. This study aimed to describe the spectrum of opportunistic infections (OIs) and associated factors among PLWHA on highly active antiretroviral therapy (HAART) at Merpati Clinic, Wangaya Regional General Hospital in Denpasar, Bali. Methods: This was a retrospective study. All of PLWHA, who still receiving HAART at Merpati Clinic from January 2018 to January 2020, who met inclusion and exclusion criteria, were included as subjects in this study. All data were collected through a review of the complete medical record of patients. Results: The prevalence of OIs in this study was 43.4%. Most PLWHA who experienced OIs were male (68.8%), age ≤40 y old with a median of age 36 y old, educational status senior high school (57.7%), married (62.1%), employed (89.7%), CD4 cell count ≥ 200 cells/µl (67.6%) and transmission route of HIV non-Intravenous (IV) drug user (99.2%). Sex, age, marital status, and CD4 cell count were significantly associated with OIs, p=0.000, p=0.005, p=0.005, and p=0.000, respectively. Conclusion: The commonest OI in this study was pulmonary tuberculosis. The presence of OIs was associated with sex, age of HIV diagnosis, marital status, and CD4 cell count. With the knowledge of OIs spectrum, clinicians are expected to be able to prevent, diagnose and treat OIs promptly to decrease the morbidity and mortality caused by OIs efficiently.

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Acceptability and feasibility of short message service to improve ART medication adherence among people living with HIV/AIDS receiving antiretroviral treatment at Adama hospital medical college, Central Ethiopia

BMC Public Health ◽

10.1186/s12889-019-7687-z ◽

2019 ◽

Vol 19 (1) ◽

Author(s):

Tamrat Endebu ◽

Alem Deksisa ◽

Warku Dugasa ◽

Ermiyas Mulu ◽

Tilahun Bogale

Keyword(s):

Medication Adherence ◽

Antiretroviral Therapy ◽

Antiretroviral Treatment ◽

Short Message Service ◽

People Living With Hiv ◽

Short Message ◽

Central Ethiopia ◽

Message Service ◽

Living With Hiv ◽

Hiv Aids

Abstract Background People living with HIV/AIDS are facing sub-optimal adherence to antiretroviral therapy. Short message service innovative strategies have been recommended by the national strategy to support medication adherence among HIV positive people. Thus, this study was conducted to examine the feasibility and acceptability of a short message service to improve medication adherence among people living with HIV/AIDS receiving Antiretroviral Treatment. Methods We conducted a cross-sectional survey, from February 5 to 30, 2018, among 422 randomly selected adults living with HIV/AIDS receiving antiretroviral treatment at Adama Hospital. Interviewer administered structured questionnaire was used to collect quantitative data on the feasibility and acceptability of short message services, socio-demographic and clinical characteristics of participants. Qualitative data were also collected from two focus groups to supplement the quantitative findings. Logistic regression analysis was performed to identify factors associated with the feasibility and acceptability of short message services. Results Of 420 participants responded to our questionnaire, about nine of ten patients (93.8%) possessed had a mobile phone. Most of the patients (90.9%) were willing to accept SMS to improve their medication adherence. Patients who were in young age, early adult, disclosed their HIV status, having cell phone always and believe short message service aid adherence were more likely to accept short messages on adherence. On the other hand, frequent ART Clinic visit and perceived low confidentiality of short message service were negatively associated with acceptability of short message service. Conclusion The acceptability of short message service on adherence to antiretroviral therapy was high among people living with HIV/AIDS central Ethiopia. Authors recommend further studies, piloting or experimenting, that validate the acceptability, feasibility, effectiveness, and scalability of the intervention.

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