scholarly journals A landmark in drug discovery based on complex natural product synthesis

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Satoshi Kawano ◽  
Ken Ito ◽  
Kenzo Yahata ◽  
Kazunobu Kira ◽  
Takanori Abe ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Natural Product ◽  
Natural Product Synthesis

scholarly journals Bridging the gap between natural product synthesis and drug discovery

2020 ◽  
Vol 37 (11) ◽  
pp. 1436-1453 ◽  
Author(s):  
Nathanyal J. Truax ◽  
Daniel Romo
Keyword(s):  
Natural Products ◽  
Drug Discovery ◽  
Natural Product ◽  
Chemical Space ◽  
Natural Product Synthesis ◽  
Chemical Information

Various synthetic strategies have been developed to explore natural products as an enduring source of chemical information useful for probing biological relevant chemical space and impacting drug discovery.

Palladium catalysed meta-C–H functionalization reactions

2016 ◽  
Vol 14 (24) ◽  
pp. 5440-5453 ◽  
Author(s):  
Aniruddha Dey ◽  
Soumitra Agasti ◽  
Debabrata Maiti
Keyword(s):  
Drug Discovery ◽  
Natural Product ◽  
Natural Product Synthesis ◽  
Material Sciences ◽  
Directing Group ◽  
Site Selective

The directing group assisted site selective C–H functionalization approach is having a continuous impact in the field of natural product synthesis, drug discovery and material sciences.

Natural Product Synthesis and Drug Discovery: Shortcomings and Successes

2017 ◽  
Vol 1 (3) ◽  
pp. 95-96
Author(s):  
Lee Pedzisa ◽  
◽  
Thomas Bannister ◽  
Keyword(s):  
Drug Discovery ◽  
Natural Product ◽  
Natural Product Synthesis

scholarly journals Functionalised Nitrogen Heterocycles and the Search for New Antibacterials and Bioactives

Synthesis ◽  
2020 ◽  
Vol 52 (11) ◽  
pp. 1602-1616 ◽  
Author(s):  
Mark G. Moloney ◽  
Muhammad Kamran Khan ◽  
Dandan Wang
Keyword(s):  
Biological Activity ◽  
Drug Discovery ◽  
Natural Product ◽  
Nitrogen Heterocycles ◽  
Natural Product Synthesis ◽  
Antibacterial Drug ◽  
Metal Chelation ◽  
Synthetic Routes

The importance of, and synthetic routes to, pyrrolidines and piperidines, along with their relevance to natural product synthesis and antibacterial drug discovery, are surveyed in the context of an extended programme of investigation from our own laboratories.1 Introduction2 Pyroglutamates2.1 Synthesised by Modification of an Existing Ring2.2 Synthesised by Construction of a New Ring3 Tetramates4 Metal Chelation5 Biological Activity6 Conclusion

Sign in / Sign up

Export Citation Format

Share Document