scholarly journals Copper nanoparticles on controlled pore glass (CPG) as highly efficient heterogeneous catalysts for “click reactions”

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Abdolrahim A. Rafi ◽  
Ismail Ibrahem ◽  
Armando Córdova
Keyword(s):  
Copper Nanoparticles ◽  
Heterogeneous Catalysts ◽  
Catalyst System ◽  
Terminal Alkynes ◽  
Click Reactions ◽  
Dipolar Cycloadditions ◽  
Organic Azides ◽  
Controlled Pore Glass ◽  
Pore Glass ◽  
High Yields

AbstractWe herein report that supported copper nanoparticles (CuNPs) on commercially available controlled pore glass (CPG), which exhibit high mechanical, thermal and chemical stability as compared to other silica-based materials, serve as a useful heterogeneous catalyst system for 1,3-dipolar cycloadditions (“click” reactions) between terminal alkynes and organic azides under green chemistry conditions. The supported CuNPs-CPG catalyst exhibited a broad substrate scope and gave the corresponding triazole products in high yields. The CuNPs-CPG catalyst exhibit recyclability and could be reuced multiple times without contaminating the products with Cu.

scholarly journals Copper Nanoparticles on Controlled Pore Glass and TEMPO for the Aerobic Oxidation of Alcohols

ChemNanoMat ◽  
2017 ◽  
Vol 4 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Ismail Ibrahem ◽  
Muhammad Naeem Iqbal ◽  
Oscar Verho ◽  
Alireza Eivazihollagh ◽  
Peter Olsén ◽  
...  
Keyword(s):  
Copper Nanoparticles ◽  
Aerobic Oxidation ◽  
Controlled Pore Glass ◽  
Oxidation Of Alcohols ◽  
Pore Glass

Calorimetric Sensor for Ethanol Using Ni2+-nitrilotriacetic Acid (NTA) Resin Immobilized Alcohol Dehydrogenase (ADH)

2020 ◽  
Vol 16 (6) ◽  
pp. 795-799
Author(s):  
YongJin Li
Keyword(s):  
Cost Effective ◽  
Nitrilotriacetic Acid ◽  
Repeated Measurements ◽  
Great Promise ◽  
Calorimetric Sensor ◽  
Controlled Pore Glass ◽  
Pore Glass ◽  
One Step ◽  
Immobilization Matrix ◽  
Enzyme Thermistor

Background: A simple, fast and economic analytical method for the determination of ethanol is important for clinical, biological, forensic and physico-legal purposes. Methods: Ni2+-NTA resin was used as an immobilization matrix for the simple one-step purification/ immobilization of his6-tagged ADH. Different alcohols with a concentration range of 0.5-50% V/V, namely methanol, ethanol and propanol were measured using prepared ADH enzyme thermistor. The ethanol content of Tsingtao beer was tested as a real sample containing alcohol. Reproducibility and stability of prepared ADH enzyme thermistor were also investigated by repeated measurements. Results: In comparison to the controlled pore glass (a common used support for the immobilization of enzyme) used in thermal biosensor, the use of Ni2+-NTA resin not only led to simple one-step purification/ immobilization by his6-tagged ADH binding to Ni2+-NTA resin, but also made the immobilizing supports reusable. The prepared biosensor can be used to determine ethanol and methanol by the calorimetric measurement. A linear range of 1 -32% (V/V) and 2-20% (V/V) was observed for ethanol and methanol, respectively. The detection limits were 0.3% (V/V) and 1% (V/V) for ethanol and methanol, respectively. The tested ethanol concentration of Tsingtao beer was 4.5% V/V, which is comparable with the labeled alcohol by volume (ABV) 4.80%. Conclusion: Ni2+-NTA resin, as an immobilization matrix in ET sensor, provides a simple one-step purification/immobilization for His6-tagged recombinase and a reusable immobilization matrix. The prepared biosensor exhibits good repeatability and stability. Such a new biosensor shows great promise for rapid, simple, and cost-effective analysis of ethanol and methanol, both in qualitative and in quantitative tests.

Improved Conditions for Solid Phase Synthesis of Oligonucleotides on PS-PEG Copolymers

1995 ◽  
Vol 50 (7) ◽  
pp. 1096-1100 ◽  
Author(s):  
Ernst Bayer ◽  
Konrad Bleicher ◽  
Martin Maier
Keyword(s):  
Electrospray Mass Spectrometry ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Chemical Properties ◽  
Oligonucleotide Synthesis ◽  
Phase Synthesis ◽  
Controlled Pore Glass ◽  
Product Identification ◽  
Pore Glass ◽  
And Chemical Properties

Polystyrene-polyethylene glycol (PS-PEG) tentacle polymers with loadings of up to 60/<μmol/g were used for standard oligonucleotide synthesis. As these resins are easy to handle and stable under reaction and cleavage conditions they may be used alternatively to controlled pore glass (CPG) as the most commonly used solid support for oligonucleotide synthesis. However, structural and chemical properties of the PS-PEG resins require modified conditions to guarantee syntheses with high coupling efficiencies. Oligonucleotides (ODN ) of various sequences and lengths have successfully been synthesized using HPLC and capillary electrophoresis (CE) for purity control. Additionally, electrospray mass spectrometry (ES-MS) was used for product identification.

Functionalized resorcin[4]arene-based coordination polymers as heterogeneous catalysts for click reactions

2021 ◽  
Vol 45 (6) ◽  
pp. 3181-3187
Author(s):  
Fei-Fei Wang ◽  
Jia-Hui Li ◽  
Hai-Yan Liu ◽  
Shu-Ping Deng ◽  
Ying-Ying Liu ◽  
...  
Keyword(s):  
Coordination Polymers ◽  
Heterogeneous Catalysts ◽  
Click Reactions

One Cu(i) and two Cd(ii) coordination polymers have been achieved using a 4-mercaptopyridine-functionalized resorcin[4]arene. 1 exhibits predominant efficiency and excellent recyclability for the synthesis of 1,2,3-triazoles and β-OH-1,2,3-triazoles.

Dansylated Aminopropyl Controlled Pore Glass:  A Model for Silica−Liquid Solvation+

Langmuir ◽  
2004 ◽  
Vol 20 (24) ◽  
pp. 10507-10516 ◽  
Author(s):  
Phillip M. Page ◽  
Chase A. Munson ◽  
Frank V. Bright
Keyword(s):  
Controlled Pore Glass ◽  
Pore Glass

Use of controlled pore glass in solid phase oligosaccharide synthesis. Application to the semiautomated synthesis of a glyconucleotide conjugate

1998 ◽  
Vol 39 (14) ◽  
pp. 1953-1956 ◽  
Author(s):  
Matteo Adinolfi ◽  
Gaspare Barone ◽  
Lorenzo De Napoli ◽  
Alfonso Iadonisi ◽  
Gennaro Piccialli
Keyword(s):  
Solid Phase ◽  
Oligosaccharide Synthesis ◽  
Controlled Pore Glass ◽  
Pore Glass

Palladium Catalyzed Synthesis of Phenylquinoxaline-Alkyne Derivatives via Sonogashira Cross Coupling Reaction

2021 ◽  
Vol 43 (1) ◽  
pp. 95-95
Author(s):  
Rifhat Bibi Rifhat Bibi ◽  
Muhammad Yaseen Muhammad Yaseen ◽  
Haseen Ahmad Haseen Ahmad ◽  
Ismat Ullah Khan Ismat Ullah Khan ◽  
Shaista Parveen Shaista Parveen ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Sonogashira Reaction ◽  
Terminal Alkynes ◽  
Vinyl Halides ◽  
Sonogashira Coupling Reaction ◽  
Quinoxaline Derivatives ◽  
Palladium Catalyzed ◽  
High Yields ◽  
Alkyne Derivatives

Transition metals mediated cross coupling methodologies provide an extremely powerful versatile pathway in organic syntheses undoubtedly, a facile route for syntheses and derivatization of biologically important heterocycles from easily available precursors. Sonogashira coupling reaction, a leading method to Csp-Csp2 bond formation is one of the most important and rapid pathways to couple aryl/vinyl halides with terminal alkynes. Current research study deals with the synthesis of alkyne substituted quinoxaline derivatives. The quinoxalines class of aromatic heterocycles exhibits a wide variety of important biological potencies. Palladium catalyzed cross coupling process provided an effective synthetic practice for the synthesis of alkyne derivatives of quinoxaline. Vareity of terminal alkynes were coupled with 2-(4-bromophenyl)quinoxaline under optimized conditions for Sonogashira reaction, affording alkyne substituted quinoxaline derivatives in high yields. The optimized reaction conditions for coupling of range of terminal alkyne with quinoxaline basic core render this process significant for designing of medicinally interesting precursors.

Immobilization of Bovine Trypsin onto Controlled Pore Glass

2013 ◽  
Vol 38 (2) ◽  
pp. 184-195 ◽  
Author(s):  
Dan Li ◽  
Nana Akyaa Ackaah-Gyasi ◽  
Benjamin K. Simpson
Keyword(s):  
Controlled Pore Glass ◽  
Bovine Trypsin ◽  
Pore Glass
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