scholarly journals Research on Golay-coded excitation in real-time imaging of high frequency ultrasound biomicroscopy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xiaochun Wang ◽  
Jun Yang ◽  
Jianjun Ji ◽  
Yusheng Zhang ◽  
Sheng Zhou
Keyword(s):  
Real Time ◽  
High Frequency ◽  
Single Pulse ◽  
Ultrasound Biomicroscopy ◽  
Image Resolution ◽  
High Frequency Ultrasound ◽  
Coded Excitation ◽  
Real Time Imaging ◽  
Detection Depth ◽  
Frequency Ultrasound

AbstractHigh frequency ultrasonic imaging provides clinicians with high-resolution diagnostic images and more accurate measurement results. The technique is now widely used in ophthalmology, dermatology, and small animal imaging. However, since ultrasonic attenuation in tissue increases rapidly with increasing frequency, the depth of detection of high frequency ultrasound in tissue is limited to a few millimeters. In this paper, a novel method of using Golay-coded excitation as a replacement for conventional single-pulse excitation in high frequency ultrasound biomicroscopy was proposed, and real-time imaging was realized. While maintaining the transmission voltage and image resolution unchanged, the detection depth can be effectively improved. The ultrasonic transmission frequency is 30 MHz and the transmission voltage is ± 60 V p-p. In this study, 4-bit, 8-bit, and 16-bit coding sequences and decoding compression were used. To verify the effectiveness of the coding sequence in real-time imaging of ultrasound biomicroscopy, we designed a 10-μm diameter line target echo experiment, an ultrasound phantom experiment, and an in vitro porcine eye experiment. The experimental results show that the code/decode method of signal processing can not only maintain a resolution consistent with that of single-pulse transmission, but can also improve the detection depth and signal-to-noise ratio.

Real-time imaging of in-vitro human middle ear using high frequency ultrasound

2015 ◽  
Vol 326 ◽  
pp. 1-7 ◽  
Author(s):  
Thomas G. Landry ◽  
James W. Rainsbury ◽  
Robert B. Adamson ◽  
Manohar L. Bance ◽  
Jeremy A. Brown
Keyword(s):  
Real Time ◽  
Middle Ear ◽  
High Frequency ◽  
High Frequency Ultrasound ◽  
Real Time Imaging ◽  
Human Middle Ear ◽  
Frequency Ultrasound

Abstract 245: Non-Invasive in vivo Assessment of the Re-Endothelialization Process Using Ultrasound Biomicroscopy in the Rat Carotid Artery Balloon Injury Model

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Samuel Röhl ◽  
Linnea Eriksson ◽  
Robert Saxelin ◽  
Mariette Lengquist ◽  
Kenneth Caidahl ◽  
...  
Keyword(s):  
Carotid Artery ◽  
High Frequency ◽  
Ultrasound Biomicroscopy ◽  
Blue Dye ◽  
High Frequency Ultrasound ◽  
Balloon Injury ◽  
En Face ◽  
In Vivo Assessment ◽  
Frequency Ultrasound

Objective: Ultrasound BioMicroscopy (UBM), or high-frequency ultrasound, is a novel technique used for assessment of anatomy and physiology small research animals. In this study, we evaluate the UBM assessment of the re-endothelialization process following denudation of the carotid artery in rats. Methods: Ultrasound BioMicroscopy data from three different experiments were analyzed. A total of 66 rats of three different strains (Sprague-Dawley, Wistar and Goto-Kakizaki) were included in this study. All animals were subjected to common carotid artery balloon injury and examined with UBM 2 and 4 weeks after injury. Re-endothelialization in UBM was measured as the length from the carotid bifurcation to the distal edge of the intimal hyperplasia. En face staining with Evans-blue dye was performed upon euthanization at 4 weeks after injury followed by tissue harvest for morphological and immunohistochemical evaluation. Results: A significant correlation (Spearman r=0.63,p<0.0001) and an agreement according to Bland-Altman test was identified when comparing all measurements of re-endothelialization in high frequency ultrasound and en face staining. Analysis by animal strain revealed a similar pattern and a significant growth in re-endothelialization length measured in UBM from 2 to 4 weeks could be identified. Immunohistochemical staining for von Willebrand factor confirmed the presence of endothelium in the areas detected as re-endothelialized by the ultrasound assessment. Conclusion: Ultrasound BioMicroscopy can be used for longitudinal in vivo assessment of the re-endothelialization following arterial injury in rats.

scholarly journals Low to Very-High Frequency Ultrasound Biomicroscopy of Cell Death

2010 ◽  
Vol 16 (S2) ◽  
pp. 1110-1111
Author(s):  
GJ Czarnota
Keyword(s):  
Cell Death ◽  
High Frequency ◽  
Ultrasound Biomicroscopy ◽  
High Frequency Ultrasound ◽  
Very High Frequency ◽  
Very High ◽  
Frequency Ultrasound

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.

High-Frequency and Ultra-High Frequency Ultrasound: Musculoskeletal Imaging up to 70 MHz

2020 ◽  
Vol 24 (02) ◽  
pp. 125-134 ◽  
Author(s):  
Domenico Albano ◽  
Giacomo Aringhieri ◽  
Carmelo Messina ◽  
Luca De Flaviis ◽  
Luca Maria Sconfienza
Keyword(s):  
High Frequency ◽  
Peripheral Nerves ◽  
Imaging Technique ◽  
Case Series ◽  
Image Resolution ◽  
Ultrastructural Changes ◽  
High Frequency Ultrasound ◽  
Ultra High Frequency ◽  
Time Dynamic ◽  
Frequency Ultrasound

AbstractMusculoskeletal (MSK) ultrasound has well-established advantages, able to investigate very small structures with high resolution and a quick and real-time dynamic evaluation with the possibility of contralateral comparison. Thus ultrasound has kept its own almost exclusive fields of application in daily clinical practice, and it is considered the first-level imaging technique to assess tendons, bursae, and capsuloligamentous structures of small peripheral joints as well as peripheral nerves. Up to now, however, clinical MSK ultrasound imaging could not go beyond the first 1 to 2 cm under the skin, using high-frequency probes up to 18 to 20 MHz with spatial resolution just below millimeters. We present the impressive technical advancements leading to image resolution as low as 30 µm using ultra-high frequency ultrasound (UHFUS) probes up to 70 MHz. High-frequency ultrasound and UHFUS, with frequencies ranging from 22 to 70 MHz, are promising tools to evaluate very superficial structures. In the MSK system, only two articles have assessed its value in limited case series. Future developments may be aimed to better assess ultrastructural changes of very superficial peripheral nerves and other thin structures such as pulleys, retinacula, and tendons.

High-frequency ultrasound biomicroscopy of the normal canine haired skin

2014 ◽  
Vol 25 (3) ◽  
pp. 176-e45
Author(s):  
Panagiotis Mantis ◽  
Dimitrios Tontis ◽  
David Church ◽  
David Lloyd ◽  
Kim Stevens ◽  
...  
Keyword(s):  
High Frequency ◽  
Ultrasound Biomicroscopy ◽  
High Frequency Ultrasound ◽  
Frequency Ultrasound
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