scholarly journals Expression of high-mobility-group-protein HMGI-C mRNA in the peripheral blood is an independent poor prognostic indicator for survival in metastatic breast cancer

2003 ◽  
Vol 88 (9) ◽  
pp. 1406-1410 ◽  
Author(s):  
C Langelotz ◽  
P Schmid ◽  
C Jakob ◽  
U Heider ◽  
K D Wernecke ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Peripheral Blood ◽  
High Mobility ◽  
Metastatic Breast ◽  
Prognostic Indicator ◽  
High Mobility Group ◽  
High Mobility Group Protein ◽  
Group Protein ◽  
Poor Prognostic Indicator

Expression of High Mobility Group Protein Family [HMGI(Y) and HMGI-C] in Human Breast Cancer

2001 ◽  
Vol 33 (4) ◽  
pp. 281-285 ◽  
Author(s):  
Jin Woo Ryu ◽  
Duck Hwan Kim ◽  
Hyung Sik Shin ◽  
Eun Sook Nam ◽  
Hyung Jee Kim
Keyword(s):  
Breast Cancer ◽  
Human Breast Cancer ◽  
High Mobility ◽  
Protein Family ◽  
High Mobility Group ◽  
Human Breast ◽  
High Mobility Group Protein ◽  
Group Protein

scholarly journals High mobility group 20B (HMG20B) is a differentially expressed gene in human metastatic breast cancer, in the brain and in the lymph nodes.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Metastatic Breast Cancer ◽  
Lymph Nodes ◽  
Differentially Expressed Gene ◽  
High Mobility ◽  
Metastatic Breast ◽  
Metastatic Tumor ◽  
High Mobility Group ◽  
Primary Tumors ◽  
The Brain

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that high mobility group 20B, encoded by HMG20B, was among the genes whose expression was most different in the brain and lymph node metastases of patients with metastatic breast cancer. HMG20B mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of HMG20B in primary tumors was significantly correlated with patient distant metastasis-free survival in patients with breast cancer. Modulation of HMG20B expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain while evading immune clearance in the lymph nodes in humans with metastatic breast cancer.

scholarly journals Characterization of high mobility group protein levels during spermatogenesis in the rat.

1984 ◽  
Vol 259 (14) ◽  
pp. 8840-8846
Author(s):  
L R Bucci ◽  
W A Brock ◽  
I L Goldknopf ◽  
M L Meistrich
Keyword(s):  
High Mobility ◽  
High Mobility Group ◽  
High Mobility Group Protein ◽  
Protein Levels ◽  
Group Protein

scholarly journals High Mobility Group Protein B1 Is an Activator of Apoptotic Response to Antimetabolite Drugs

2007 ◽  
Vol 73 (1) ◽  
pp. 260-269 ◽  
Author(s):  
Natalia Krynetskaia ◽  
Hongbo Xie ◽  
Slobodan Vucetic ◽  
Zoran Obradovic ◽  
Evgeny Krynetskiy
Keyword(s):  
High Mobility ◽  
High Mobility Group ◽  
Apoptotic Response ◽  
High Mobility Group Protein ◽  
Group Protein
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