scholarly journals Release of somatostatin and its role in the mediation of the anti-inflammatory effect induced by antidromic stimulation of sensory fibres of rat sciatic nerve

1998 ◽  
Vol 123 (5) ◽  
pp. 936-942 ◽  
Author(s):  
János Szolcsányi ◽  
Zsuzsanna Helyes ◽  
Gábor Oroszi ◽  
József Németh ◽  
Erika Pintér
Keyword(s):  
Sciatic Nerve ◽  
Rat Sciatic Nerve ◽  
Antidromic Stimulation ◽  
Anti Inflammatory ◽  
Stimulation Of ◽  
Inflammatory Effect

scholarly journals Reduced Heat Generation During Magnetic Stimulation of Rat Sciatic Nerve Using Current Waveform Truncation

2019 ◽  
Vol 27 (5) ◽  
pp. 937-946
Author(s):  
Zachary B. Kagan ◽  
John T. Mize ◽  
Pragya Kosta ◽  
Gianluca Lazzi ◽  
Richard A. Normann ◽  
...  
Keyword(s):  
Sciatic Nerve ◽  
Heat Generation ◽  
Magnetic Stimulation ◽  
Current Waveform ◽  
Rat Sciatic Nerve ◽  
Stimulation Of

Anti-Inflammatory Effects of Counterirritants

1958 ◽  
Vol 195 (3) ◽  
pp. 712-718 ◽  
Author(s):  
C. Laden ◽  
R. Quentin Blackwell ◽  
L. S. Fosdick
Keyword(s):  
Pleural Cavity ◽  
Fluid Loss ◽  
Time Interval ◽  
Hypophysectomized Rats ◽  
Inflammatory Edema ◽  
Anti Inflammatory ◽  
Pituitary Adrenal Axis ◽  
Plaster Casts ◽  
Stimulation Of ◽  
Inflammatory Effect

Experimental inflammatory edema was induced by injecting an irritant solution into the pleural cavity of rats. The volume of fluid found in the pleural cavity after a specified time interval was used as a measure of the degree of inflammation produced. The effect of counterirritants on reducing pleural inflammation was studied. Injection of irritants into the knee joint of the rat was found to reduce the amount of pleural inflammation formed. The anti-inflammatory effect observed could not be explained by loss of fluid into the injected knee, nor by stimulation of the pituitary-adrenal axis. The effect was still present in hypophysectomized rats and adrenalectomized rats. The use of plaster casts to prevent fluid loss into the injected leg did not block the reduction in pleural inflammation. It was suggested that counterirritants release some substance or substances from the tissues which they damage, which is carried by the blood and can exert an anti-inflammatory effect in another part of the animal.

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