scholarly journals Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation

2005 ◽  
Vol 13 (1) ◽  
pp. 74-81 ◽  
Author(s):  
L Zhang ◽  
S Sharma ◽  
J M Hershman ◽  
G A Brent ◽  
S M Dubinett ◽  
...  
2020 ◽  
Vol 15 (4) ◽  
pp. 1934578X2091503
Author(s):  
Sang Hoon Lee ◽  
Ah-Reum Han ◽  
Unwoo Kang ◽  
Jin-Baek Kim ◽  
Eun Kyoung Seo ◽  
...  

Radiation therapy is a very effective tool for the treatment of advanced human lung cancers. However, as one of its malignancy-promoting behaviors, ionizing radiation (IR) increases cell migration and radiation resistance in several lung cancer cells, including non-small cell lung cancer (NSCLC) cells. As part of our ongoing search for potent radiotherapy enhancers from medicinal herbs, a chloroform-soluble fraction of the roots of Angelica dahurica was subjected to phytochemical investigation, leading to the isolation of 8 furanocoumarins. Of these, psoralen (1), xanthotoxin (2), and bergapten (3) inhibited IR-induced migration at a non-cytotoxic concentration (50 μM) in human NSCLC A549 cells. This study is the first to report on the inhibitory activities of these constituents of A. dahurica against IR-induced cancer metastasis.


2016 ◽  
Vol 17 (4) ◽  
pp. 390-399 ◽  
Author(s):  
Ayman Oweida ◽  
Zeinab Sharifi ◽  
Hani Halabi ◽  
Yaoxian Xu ◽  
Siham Sabri ◽  
...  

2015 ◽  
Vol 10 (2) ◽  
pp. 126-130
Author(s):  
Yong Tian ◽  
Cong Chen ◽  
Yu Zhang ◽  
Zhen Zhang ◽  
Haiyan Xie

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