The impact of genotyping error on family-based analysis of quantitative traits

The impact of temperature and light/dark cycle on morphological traits of Platytrombidium fasciatum was examined in larvae obtained from field-collected females. The eggs laid by 65 females at laboratory conditions were assigned to four experimental groups. Varied thermal conditions affected the values of nine out of 46 (nonparametric MANOVA) and 26 out of 37 (LDA) morphometric traits in larvae. As many as six quantitative traits differed significantly irrespective of the method (MANOVA, LDA) applied. The analysis of the metric traits within the dorsal sclerites revealed that the lower mean temperature over the period of egg incubation, translated into longer duration of development, was associated with an increase in distance between the bases of 3rd pair of non-sensillary setae on scutum at the decrease in distance between the bases of 2nd pair of non-sensillary setae as well as in distance between the level of sensilla and the posterior edge of the sclerite. In the case of 40 measurable traits in larvae of P. fasciatum, the variability going beyond the hitherto knowledge on the species was observed.

Download Full-text

A Randomized Controlled Trial of the Impact of a Family-Based Adolescent Depression Intervention on both Youth and Parent Mental Health Outcomes

Journal of Abnormal Child Psychology ◽

10.1007/s10802-017-0292-7 ◽

2017 ◽

Vol 46 (1) ◽

pp. 169-181 ◽

Cited By ~ 6

Author(s):

Lucinda A. Poole ◽

Tess Knight ◽

John W. Toumbourou ◽

Dan I. Lubman ◽

Melanie D. Bertino ◽

...

Keyword(s):

Mental Health ◽

Randomized Controlled Trial ◽

Health Outcomes ◽

Adolescent Depression ◽

Controlled Trial ◽

Parent Mental Health ◽

Randomized Controlled ◽

Family Based ◽

The Impact ◽

Depression Intervention

Download Full-text

Evolution of Drosophila insecticide resistance

Genome ◽

10.1139/g93-001 ◽

1993 ◽

Vol 36 (1) ◽

pp. 1-7 ◽

Cited By ~ 42

Author(s):

R. A. Morton

Keyword(s):

Insecticide Resistance ◽

Quantitative Traits ◽

Molecular Genetic ◽

Resistance Evolution ◽

Target Molecules ◽

Genetic Techniques ◽

The Cost ◽

The Impact ◽

The Relationship ◽

Selection Of

The impact of insecticide resistance is well documented. It includes the toxic effects of pesticides on the environment and the cost of the increased amounts of insecticides required to effectively control resistant insects. Resistance evolves by the selection of genes that confer tolerance to insecticides. Several resistance genes have been identified and cloned in Drosophila, including genes for mutant target molecules and genes that increase insecticide degradation. Drosophila is a useful system to understand the evolution of quantitative traits in general as well as the population genetics of insecticide resistance. Through it, we may hope to understand the relationship between discrete genetic change and continuously varying characters. In addition, molecular genetic techniques developed using Drosophila can eventually be transferred to other insects in order to help control pest populations.Key words: insecticide resistance, evolution of tolerance, selection of resistant genes, molecular genetics, Drosophila.

Download Full-text

A blocking Gibbs sampling method to detect major genes with phenotypic data from a diallel mating

Genetics Research ◽

10.1017/s0016672304006718 ◽

2004 ◽

Vol 83 (2) ◽

pp. 143-154 ◽

Cited By ~ 4

Author(s):

WEN ZENG ◽

SUJIT GHOSH ◽

BAILIAN LI

Keyword(s):

Gibbs Sampling ◽

Quantitative Traits ◽

Sampling Method ◽

Major Gene ◽

Data Set ◽

Major Genes ◽

Statistical Inferences ◽

The Impact ◽

Half Diallel ◽

Diallel Mating

Diallel mating is a frequently used design for estimating the additive and dominance genetic (polygenic) effects involved in quantitative traits observed in the half- and full-sib progenies generated in plant breeding programmes. Gibbs sampling has been used for making statistical inferences for a mixed-inheritance model (MIM) that includes both major genes and polygenes. However, using this approach it has not been possible to incorporate the genetic properties of major genes with the additive and dominance polygenic effects in a diallel mating population. A parent block Gibbs sampling method was developed in this study to make statistical inferences about the major gene and polygenic effects on quantitative traits for progenies derived from a half-diallel mating design. Using simulated data sets with different major and polygenic effects, the proposed method accurately estimated the major and polygenic effects of quantitative traits, and possible genotypes of parents and progenies. The impact of specifying different prior distributions was examined and was found to have little effect on inference on the posterior distribution. This approach was applied to an experimental data set of Loblolly pine (Pinus taeda L.) derived from a 6-parent half-diallel mating. The result indicated that there might be a recessive major gene affecting height growth in this diallel population.

Download Full-text