scholarly journals Comparison of de-epithelialized amniotic membrane transplantation and conjunctival autograft after primary pterygium excision

Eye ◽  
2006 ◽  
Vol 22 (1) ◽  
pp. 107-112 ◽  
Author(s):  
F Memarzadeh ◽  
A K Fahd ◽  
N Shamie ◽  
R S Chuck
2020 ◽  
Author(s):  
ASHOK JHA ◽  
Abhay Simba

Abstract Background: To compare conjunctival autograft and combined amniotic membrane mini-simple limbal epithelial transplant after primary pterygium excision Methods: A prospective randomized interventional study was conducted on 264 eyes with Primary Pterygium.The patients were divided into Group I (conjunctival autograft) and Group II (mini-simple limbal epithelial transplant). 133 eyes in Group I underwent pterygium excision with a conjunctival autograft using fibrin glue. 131 eyes in Group II underwent mini Simple Limbal Epithelial Transplant with amniotic membrane using fibrin glue. Post-operatively, the patients were reviewed on day 1,3,7,14 & 30 and then at three,six and nine months. Primary outcome measure was the recurrence rate whereas the secondary outcome measures were the intraoperative time and other complications.Recurrence rate was calculated using Fisher’s exact test. Variables like age , preoperative BCVA , operative time and the dimensions of graft were compared using unpaired t test . Other baseline characteristics like gender, Laterality, grades of pterygium(I-III),Occupation and indication of surgery were expressed between the two groups using Pearson’s Chi-Square test. Results: Two hundred and thirty three eyes(118 in group I and 115 in group II) could complete nine months follow-up period. Recurrence was seen in 2(1.6%) cases in group I whereas 3 cases (2.6%) had recurrence in group II(p=0.681).Operative time for group (II) (20.33±1.28 min) was significantly higher (p<0.001) than group I (12.01±1.26). Graft displacement occurred in one case in group II (p=0.999). Conclusions: Despite a longer time,(p<0.001) mini-SLET seems to be a viable and equally effective alternative to CAG in the management of primary pterygium ,especially in cases where conjunctiva needs to be spared.Ethical Clearance Certificate Number : 29/MH/2015 dated 11 Aug 2015


Cornea ◽  
2016 ◽  
Vol 35 (6) ◽  
pp. 823-826 ◽  
Author(s):  
N. Venkatesh Prajna ◽  
Lumbini Devi ◽  
Suganya K. Seeniraj ◽  
Jeremy D. Keenan

2020 ◽  
Author(s):  
ASHOK JHA ◽  
Abhay Simba

Abstract The authors have requested that this preprint be withdrawn due to author disagreement.


Cornea ◽  
2017 ◽  
Vol 36 (3) ◽  
pp. e7-e8
Author(s):  
Venkatesh N. Prajna ◽  
Lumbini Devi ◽  
Suganya K. Seeniraj ◽  
Jeremy D. Keenan

2021 ◽  
Vol 10 (23) ◽  
pp. 5711
Author(s):  
Miriam Idoipe ◽  
Borja de la Sen-Corcuera ◽  
Ronald M. Sánchez-Ávila ◽  
Carmen Sánchez-Pérez ◽  
María Satué ◽  
...  

This prospective and comparative study aimed to compare the use of a conjunctival autograft (CAG), plasma rich in growth factors fibrin membrane (mPRGF) or amniotic membrane transplantation (AMT) in primary pterygium surgery. Patients were assigned for surgery with CAG (group A), mPRGF (group B), or AMT (group C). Pterygium recurrence, Best Corrected Visual Acuity (BCVA), graft size (measured with anterior segment optical coherence tomography (AS-OCT)), and ocular surface symptoms (visual analogue scale (VAS) and ocular surface disease index (OSDI)) were evaluated. Thirteen eyes in group A, 26 in group B, and 10 in group C were evaluated. No changes in BCVA (p > 0.05) were found. Recurrence cases for groups A, B, and C were none, two, and two, respectively, and three cases of pyogenic granulomas in group A. The horizontal/vertical graft size was lower in group B vs group A (p < 0.05) from months 1 to 12. The improvement in VAS frequency for groups A, B, and C was: 35.5%, 86.2%, and 39.1%, respectively. The OSDI scale reduction for groups A, B, and C was: 12.7%, 39.0%, and 84.1%. The use of the three surgical techniques as a graft for primary pterygium surgery was safe and effective, showing similar results. The mPRGF graft represents an autologous novel approach for pterygium surgery.


2011 ◽  
pp. 118-122
Author(s):  
Van Nam Phan ◽  
Thanh Hai Nguyen ◽  
Nhu Vinh Tuyen Pham

The study of primary pterygium excision with amniotic membrane transplantation contribute to the treament of pterygium. Objectives: To evaluate the outcome of primary pterygium excision with amniotic membrane transplantation. Methods: prospective study, clinical case study with no control. Results: 69,44% patients with primary pterygia were mainly at the age 20 to 60 years. Pterygia at level III were 71,15%. After surgery visual acuity was not remarkably increased while astigmation was reduced remarkably. Good result was 93,67%. Recurrent rate at 3 months after surgery was 2,08%. Conclusion: Pterygium excision with amniotic membrane transplantation has many benefits like highly cosmetic, meet the patient’s demand and saving conjuntiva. This method has the same recurrent rate compare wih other methods. Key words: pterygium, amniotic membrane, recurrent, conjuntiva, transplantation.


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