scholarly journals Alpha-Tocopherol Succinate, But Not Alpha-Tocopherol Or Other Vitamin E Analogs Stimulates Prolactin And Growth Hormone Release From Rat Anterior Pituitary Cells in vitro

1994 ◽  
Vol 11 (4) ◽  
pp. 265-265 ◽  
Author(s):  
M Badamchian ◽  
B Spangelo ◽  
Y Hagiwara ◽  
H Hagiwara ◽  
H Veyama ◽  
...  
1985 ◽  
Vol 248 (4) ◽  
pp. E438-E442
Author(s):  
A. M. Judd ◽  
K. Koike ◽  
R. M. MacLeod

Arachidonate and its metabolites increase growth hormone release in vitro. A study was designed to determine whether arachidonate release from anterior pituitary cells is modified by growth hormone-releasing factor (GRF) or somatostatin (SRIF). Cultured pituitary cells were incubated with [3H]arachidonate to esterify the long-chain fatty acid into cellular lipids. The cells were extensively washed with medium containing no [3H]arachidonate and then incubated with GRF and/or SRIF for 30 min. The incubation medium was then extracted with ethyl acetate, and following thin-layer chromatographic separation, the radioactivity in the [3H]arachidonate band was measured. GRF in a concentration-dependent manner (1-30 nM) stimulated growth hormone and arachidonate release, whereas SRIF (100 nM) blocked the GRF-induced increase of growth hormone and arachidonate release. The effects of GRF on growth hormone and arachidonate were evident at time intervals as brief as 5 min. These findings support the hypothesis that arachidonate may play a role in the GRF-induced growth hormone release.


1989 ◽  
Vol 50 (5) ◽  
pp. 513-518 ◽  
Author(s):  
Robert Drouhault ◽  
Pierre Vacher ◽  
Jean P. David ◽  
Anne M. Courtes ◽  
Nidaravone Vilayleck ◽  
...  

1983 ◽  
Vol 37 (6) ◽  
pp. 473-475 ◽  
Author(s):  
Susan N. Perkins ◽  
William S. Evans ◽  
Michael O. Thorner ◽  
Michael.J. Cronin

Life Sciences ◽  
1985 ◽  
Vol 36 (6) ◽  
pp. 549-555 ◽  
Author(s):  
György Rappay ◽  
Gábor B. Makara ◽  
Sándor Bajusz ◽  
Iván Nagy

1994 ◽  
Vol 5 (3) ◽  
pp. 145-150 ◽  
Author(s):  
Mahnaz Badamchian ◽  
Bryan L. Spangelo ◽  
Yongde Bao ◽  
Yoshihide Hagiwara ◽  
Hideaki Hagiwara ◽  
...  

1990 ◽  
Vol 40 (4) ◽  
pp. 887-892 ◽  
Author(s):  
Iván Nagy ◽  
Gábor B. Makara ◽  
Vera Garamvölgyi ◽  
Sándor Bajusz ◽  
Erzsébet Széll ◽  
...  

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