scholarly journals Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Andrey V. Kajava ◽  
Karsten Klopffleisch ◽  
Shuhua Chen ◽  
Kay Hofmann
Keyword(s):  
Heterokaryon Incompatibility ◽  
Incompatibility Factor

Heterokaryon-Incompatibility Factor Interaction in Tests between Neurospora Mutants

Science ◽  
1962 ◽  
Vol 138 (3547) ◽  
pp. 1342-1343 ◽  
Author(s):  
F. J. De Serres
Keyword(s):  
Heterokaryon Incompatibility ◽  
Incompatibility Factor ◽  
Factor Interaction

scholarly journals A CLASS OF GENES AFFECTING B FACTOR-REGULATED DEVELOPMENT IN SCHIZOPHYLLUM COMMUNE

Genetics ◽  
1976 ◽  
Vol 82 (3) ◽  
pp. 423-428
Author(s):  
Celia Dubovoy
Keyword(s):  
Genetic Factor ◽  
Schizophyllum Commune ◽  
Nuclear Migration ◽  
Complex Pattern ◽  
Developmental Phase ◽  
Linear Map ◽  
Incompatibility Factor ◽  
Complementation Groups ◽  
Cluster A ◽  
Specific Phase

ABSTRACT Twelve mutations affecting nuclear migration, a major developmental phase in Schizophyllum commune, display a complex pattern of complementation and recombination. They are expressed only when a genetic factor controlling this phase of development, the B incompatibility factor, is operative. All twelve mutations are linked to the B factor, nine in a cluster and three in distinct loci outside the cluster. A linear map cannot be constructed from the frequency of recombination. Complementation maps are not linear. There is little correlation between the complementation groups and the groups based on recombination. Many pairs of mutations that do not complement recombine with frequencies of 1.1% to 26.9%. The genes represented by the twelve mutations are located in a linked group of about 18 known genes involved in the specific phase of development controlled by the B factor.

ESCAPE FROM MATING-TYPE INCOMPATIBILITY IN BISEXUAL (A + a) NEUROSPORA HETEROKARYONS

1975 ◽  
Vol 17 (3) ◽  
pp. 441-449 ◽  
Author(s):  
A. M. DeLange ◽  
A. J. F. Griffiths
Keyword(s):  
Mating Type ◽  
Loss Of Function ◽  
Wild Type ◽  
Opposite Mating Type ◽  
Type Locus ◽  
Heterokaryon Incompatibility ◽  
Recessive Mutant ◽  
Type Rate ◽  
Wild Type Rate ◽  
Incompatibility Locus

In Neurospora crassa, strains of opposite mating type generally do not form stable heterokaryons because the mating type locus acts as a heterokaryon incompatibility locus. However, when one A and one a strain, having complementing auxotrophic mutants, are placed together on minimal medium, growth may occur, although the growth is generally slow. In this study, escape from such slow growth to that at a wild type or near-wild type rate was observed. The escaped cultures are stable heterokaryons, mostly having lost the mating type allele function from one component nucleus, so that the nuclear types are heterokaryon compatible. Either A or a mating type can be lost. This loss of function has been attributed to deletion since only one nuclear type could be recovered in all heterokaryons except one, but deletion spanning adjacent loci has been directly demonstrated in a minority of cases. Alternatively when one component strain is tol and the other tol+ (tol being a recessive mutant suppressing the heterokaryon incompatibility associated with mating type), escape may occur by the deletion or mutation of tol+, also resulting in heterokaryon compatibility. An induction mechanism for escape is speculated upon.

scholarly journals Isolation of Neurospora crassa A mating type mutants by repeat induced point (RIP) mutation.

Genetics ◽  
1992 ◽  
Vol 132 (1) ◽  
pp. 125-133 ◽  
Author(s):  
N L Glass ◽  
L Lee
Keyword(s):  
Neurospora Crassa ◽  
Mating Type ◽  
Single Copy ◽  
Open Reading Frame ◽  
Sexual Cycle ◽  
Reading Frame ◽  
Heterokaryon Incompatibility ◽  
Functional Regions ◽  
A Genome ◽  
Ascospore Formation

Abstract In the filamentous fungus, Neurospora crassa, mating type is regulated by a single locus with alternate alleles, termed A and a. The mating type alleles control entry into the sexual cycle, but during vegetative growth they function to elicit heterokaryon incompatibility, such that fusion of A and a hypha results in death of cells along the fusion point. Previous studies have shown that the A allele consists of 5301 bp and has no similarity to the a allele; it is found as a single copy and only within the A genome. The a allele is 3235 bp in length and it, too, is found as a single copy within the a genome. Within the A sequence, a single open reading frame (ORF) of 288 amino acids (mt A-1) is thought to confer fertility and heterokaryon incompatibility. In this study, we have used repeat induced point (RIP) mutation to identify functional regions of the A idiomorph. RIP mutations in mt A-1 resulted in the isolation of sterile, heterokaryon-compatible mutants, while RIP mutations generated in a region outside of mt A-1 resulted in the isolation of mutants capable of mating, but deficient in ascospore formation.

Characterization of hch , the Podospora anserina homolog of the het-c heterokaryon incompatibility gene of Neurospora crassa

2000 ◽  
Vol 38 (1) ◽  
pp. 39-47 ◽  
Author(s):  
Sven J. Saupe ◽  
Corinne Clavé ◽  
Martine Sabourin ◽  
Joël Bégueret
Keyword(s):  
Neurospora Crassa ◽  
Podospora Anserina ◽  
Heterokaryon Incompatibility

Heterokaryon incompatibility blocks virus transfer among natural isolates of black Aspergilli

1997 ◽  
Vol 32 (3) ◽  
pp. 209-217 ◽  
Author(s):  
A. D. van Diepeningen ◽  
Alfons J. M. Debets ◽  
Rolf F. Hoekstra
Keyword(s):  
Heterokaryon Incompatibility ◽  
Black Aspergilli ◽  
Virus Transfer ◽  
Natural Isolates

Heterokaryon incompatibility function of barrage-associated vegetative incompatibility genes (vic) inCryphonectria parasitica

Mycologia ◽  
2006 ◽  
Vol 98 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Myron L. Smith ◽  
Carmen C. Gibbs ◽  
Michael G. Milgroom
Keyword(s):  
Vegetative Incompatibility ◽  
Heterokaryon Incompatibility
Sign in / Sign up

Export Citation Format

Share Document