Chapter 9. Male-Mediated F1 Effects in Mice Exposed to Di(2-ethylhexyl)phthalate (DEHP)

Author(s):  
MaLgorzata M. Dobrzynska ◽  
Urszula Czajka ◽  
Ewa J. Tyrkiel
Keyword(s):  
2000 ◽  
Vol 86 (2) ◽  
pp. 92-100 ◽  
Author(s):  
Majken DalgaardNote ◽  
Grete Ostergaard ◽  
Henrik Rye Lam ◽  
Ernst V. Hansen ◽  
Ole Ladefoged

1998 ◽  
Vol 38 (2) ◽  
pp. 185-192 ◽  
Author(s):  
M. J. Bauer ◽  
R. Herrmann ◽  
A. Martin ◽  
H. Zellmann

Large amounts of phthalic acid esters (PAEs) are leached from plastics dumped at municipal landfills. This leachate transports PAEs either adsorbed on particulate matter or in dissolved phase. Dissolved organic macromolecules, mainly humic-like substances, enhance the solubility of PAEs. In the biochemical environments of municipal landfills short chain PAEs can be degraded by base-catalyzed hydrolysis or by microorganisms which enzymatically split the side chains. However, there is no cleavage of the aromatic ring. Long chain PAEs like di-(2-ethylhexyl) phthalate are neither degraded abiotically nor by microorganisms. Hence, these PAEs can be leached and washed out of leaky landfills into the groundwater and thus continue to be a threat to the aquatic environment. Only a combined UV radiation/ozonation treatment is capable of fully destroying PAEs.


Author(s):  
Nadeem Ali ◽  
Nabil A. Alhakamy ◽  
Iqbal M. I. Ismail ◽  
Ehtisham Nazar ◽  
Ahmed Saleh Summan ◽  
...  

In this study, we measured the occurrence of organophosphate esters (OPEs) and phthalates in the settled dust (floor and air conditioner filter dust) and in suspended particulate matter (PM10) from different microenvironments (households (n = 20), offices (n = 10) and hotels (n = 10)) of Jeddah, Saudi Arabia. Bis (2-Ethylhexyl) phthalate (DEHP) was the major pollutant (contributing >85% of total chemicals burden) in all types of indoor dust with a concentration up to 3,901,500 ng g−1. While dibutyl phthalate (DBP) and DEHP together contributed >70% in PM10 (1900 ng m−3), which indicate PM10 as a significant source of exposure for DBP and DEHP in different Saudi indoor settings. Tris (1-chloro-2-propyl) phosphate (TCPP) was the major OPE in PM10 with a concentration of up to 185 ng m−3 and the occurrence of OPEs in indoor dust varied in studied indoor settings. The estimated daily intake (EDI) of studied chemicals via dust ingestion and inhalation of PM10 was below the reference dose (RfD) of individual chemicals. However, estimated incremental lifetime cancer risk (ILCR) with moderate risk (1.5 × 10−5) for Saudi adults and calculated hazardous index (HI) of >1 for Saudi children from DEHP showed a cause of concern to the local public health.


2021 ◽  
Vol 69 (4) ◽  
pp. 1291-1299
Author(s):  
Xue-Yan Dai ◽  
Xiao-Wei Li ◽  
Shi-Yong Zhu ◽  
Mu-Zi Li ◽  
Yi Zhao ◽  
...  

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