Determination of neodymium with 1-(2-pyridylazo)-2-naphthol by high-order derivative spectrophotometry. Application to the determination of neodymium in glasses

The Analyst ◽  
1988 ◽  
Vol 113 (3) ◽  
pp. 429-431 ◽  
Author(s):  
J. Hernández Méndez ◽  
B. Moreno Cordero ◽  
J. L. Pérez Pavón ◽  
J. Cerdá Miralles
Keyword(s):  
High Order ◽  
Derivative Spectrophotometry ◽  
Order Derivative ◽  
High Order Derivative

High-order derivative spectrophotometric determination of uranium in a cationic micellar medium

The Analyst ◽  
1995 ◽  
Vol 120 (6) ◽  
pp. 1809 ◽  
Author(s):  
Narinder Kumar Agnihotri ◽  
Vinay Kumar Singh ◽  
Har Bhajan Singh
Keyword(s):  
Spectrophotometric Determination ◽  
High Order ◽  
Order Derivative ◽  
Micellar Medium ◽  
High Order Derivative

Simultaneous 2nd Order Derivative Spectrophotometry Determination of Sorbic and Benzoic Acids in Soft Drinks

1992 ◽  
Vol 25 (12) ◽  
pp. 2367-2376 ◽  
Author(s):  
J. C. Garcia Castro ◽  
M. A. Rodriguez Delgado ◽  
M. J. Sanchez ◽  
F. Garcia Montelongo
Keyword(s):  
Soft Drinks ◽  
Derivative Spectrophotometry ◽  
Order Derivative ◽  
Benzoic Acids

scholarly journals High-performance liquid chromatography and derivative spectrophotometry for simultaneous determination of pravastatin and fenofibrate in the dosage form

2014 ◽  
Vol 64 (4) ◽  
pp. 433-446 ◽  
Author(s):  
Mohamed M. Hefnawy ◽  
Mostafa S. Mohamed ◽  
Mohammed A. Abounassif ◽  
Amer M. Alanazi ◽  
Gamal A. E. Mostafa
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Simultaneous Determination ◽  
High Performance ◽  
Particle Diameter ◽  
Second Order ◽  
Derivative Spectrophotometry ◽  
Order Derivative ◽  
Calibration Curves

Abstract High performance liquid chromatography (HPLC) and second-order derivative spectrophotometry have been used for simultaneous determination of pravastatin (PS) and fenofibrate (FF) in pharmaceutical formulations. HPLC separation was performed on a phenyl HYPERSIL C18 column (125 mm × 4.6 mm i.d., 5 μm particle diameter) in the isocratic mode using a mobile phase acetonitrile/0.1 % diethyl amine (50:50, V/V, pH 4.5) pumped at a flow rate of 1.0 mL min-1. Measurement was made at 240 nm. Both drugs were well resolved on the stationary phase, with retention times of 2.15 and 5.79 min for PS and FF, respectively. Calibration curves were linear (R = 0.999 for PS and 0.996 for FF) in the concentration range of 5-50 and 20-200 µg mL-1 for PS and FF, respectively. Pravastatin and fenofibrate were quantitated in combined preparations also using the second-order derivative response at 237.6 and 295.1 nm for PS and FF, respectively. Calibration curves were linear, with the correlation coefficient R = 0.999 for pravastatin and fenofibrate, in the concentration range of 5-20 and 3-20 µg mL-1 for PS and FF, respectively. Both methods were fully validated and compared, the results confirmed that they were highly suitable for their intended purpose.

Sign in / Sign up

Export Citation Format

Share Document