Determination of the in vivo pharmacokinetics of palladium-bacteriopheophorbide (WST09) in EMT6 tumour-bearing Balb/c mice using graphite furnace atomic absorption spectroscopy

2004 ◽  
Vol 3 (11-12) ◽  
pp. 1006 ◽  
Author(s):  
Pierre Herv� Brun ◽  
Jennifer L. DeGroot ◽  
Eva F. Gudgin Dickson ◽  
Mohsen Farahani ◽  
Roy H. Pottier
Keyword(s):  
Atomic Absorption ◽  
Absorption Spectroscopy ◽  
Atomic Absorption Spectroscopy ◽  
Graphite Furnace ◽  
Tumour Bearing ◽  
Graphite Furnace Atomic Absorption ◽  
In Vivo Pharmacokinetics

Determination of Copper in Infant Formula by Graphite Furnace Atomic Absorption Spectroscopy with a L’vov Platform

1986 ◽  
Vol 69 (1) ◽  
pp. 60-64 ◽  
Author(s):  
Donald J Hutchinson ◽  
Francis J Disinski ◽  
Christy A Nardelli
Keyword(s):  
Atomic Absorption ◽  
Infant Formula ◽  
Absorption Spectroscopy ◽  
Atomic Absorption Spectroscopy ◽  
Graphite Furnace ◽  
Matrix Interferences ◽  
Graphite Furnace Atomic Absorption ◽  
Triton X ◽  
Determination Of Copper

Abstract A rapid method for the determination of sub-part-per-million levels of copper in infant formula, which does not require decomposition of the sample matrix before analysis, has been developed. The method uses L’vov platform graphite furnace atomic absorption spectroscopy (GFAAS), a technique that greatly reduces matrix interferences limiting the applicability of normal GFAAS. The sample preparation consists of dilution of a weighed sample of infant formula to a known volume with a 0.5% solution of Triton X-100 in deionized water. The accuracy of the method, as assessed from the results of overspike recovery studies (96.5-101.3% recovery) for different matrix types and comparison to results generated with alternative methodologies, can be considered excellent. The overall precision of the method ranges from 2.5 to 4.3% RSD for different matrix types.

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