Silica nanoparticle assisted DNA assays for optical signal amplification of conjugated polymer based fluorescent sensors

2007 ◽  
pp. 3553 ◽  
Author(s):  
Yusong Wang ◽  
Bin Liu
Keyword(s):  
Conjugated Polymer ◽  
Signal Amplification ◽  
Silica Nanoparticle ◽  
Optical Signal ◽  
Fluorescent Sensors ◽  
Dna Assays

scholarly journals Signal Amplification in an Optical and Dielectric Biosensor Employing Liquid Crystal-Photopolymer Composite as the Sensing Medium

Biosensors ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 81
Author(s):  
Hassanein Shaban ◽  
Shih-Chun Yen ◽  
Mon-Juan Lee ◽  
Wei Lee
Keyword(s):  
Dielectric Constant ◽  
Liquid Crystal ◽  
Uv Irradiation ◽  
Signal Amplification ◽  
Limit Of Detection ◽  
Optical Signal ◽  
Uv Exposure ◽  
Dielectric Anisotropy ◽  
Optical Texture ◽  
Potential Development

An optical and dielectric biosensor based on a liquid crystal (LC)–photopolymer composite was established in this study for the detection and quantitation of bovine serum albumin (BSA). When the nematic LC E7 was doped with 4-wt.% NOA65, a photo-curable prepolymer, and photopolymerized by UV irradiation at 20 mW/cm2 for 300 s, the limit of detection determined by image analysis of the LC optical texture and dielectric spectroscopic measurements was 3400 and 88 pg/mL for BSA, respectively, which were lower than those detected with E7 alone (10 μg/mL BSA). The photopolymerized NOA65, but not the prepolymer prior to UV exposure, contributed to the enhanced optical signal, and UV irradiation of pristine E7 in the absence of NOA65 had no effect on the optical texture. The effective tilt angle θ, calculated from the real-part dielectric constant ε’, decreased with increasing BSA concentration, providing strong evidence for the correlation of photopolymerized NOA65 to the intensified disruption in the vertically oriented LC molecules to enhance the optical and dielectric signals of BSA. The optical and dielectric anisotropy of LCs and the photo-curable dopant facilitate novel quantitative and signal amplification approaches to potential development of LC-based biosensors.

Theory of optical signal amplification and processing by quantum-dot semiconductor optical amplifiers

2004 ◽  
Vol 69 (23) ◽  
Author(s):  
M. Sugawara ◽  
H. Ebe ◽  
N. Hatori ◽  
M. Ishida ◽  
Y. Arakawa ◽  
...  
Keyword(s):  
Quantum Dot ◽  
Signal Amplification ◽  
Optical Amplifiers ◽  
Semiconductor Optical Amplifiers ◽  
Optical Signal

Highly sensitive conjugated polymer fluorescent sensors based on benzochalcogendiazole for nickel ions in real-time detection

2014 ◽  
Vol 2 (35) ◽  
pp. 7402-7410 ◽  
Author(s):  
Yunxiang Lei ◽  
Hui Li ◽  
Wenxia Gao ◽  
Miaochang Liu ◽  
Jiuxi Chen ◽  
...  
Keyword(s):  
Real Time ◽  
Conjugated Polymer ◽  
Fluorescent Sensors ◽  
Sensitive Detection ◽  
Nickel Ions ◽  
Highly Sensitive ◽  
Real Time Detection ◽  
Highly Sensitive Detection

Two conjugated polymer fluorescent sensors using a benzochalcogendiazole unit and a triazole unit as cooperative receptors were synthesized for the highly sensitive detection of nickel ions.

Conjugated polymer-hybridized silica nanoparticle as a fluorescent sensor for cysteine

2016 ◽  
Vol 73 (9) ◽  
pp. 2447-2456 ◽  
Author(s):  
Geunseok Jang ◽  
Taek Seung Lee
Keyword(s):  
Conjugated Polymer ◽  
Fluorescent Sensor ◽  
Silica Nanoparticle

Reversible Gating of Plasmonic Coupling for Optical Signal Amplification

2016 ◽  
Vol 8 (28) ◽  
pp. 18157-18164 ◽  
Author(s):  
Christopher G. Khoury ◽  
Andrew M. Fales ◽  
Tuan Vo-Dinh
Keyword(s):  
Signal Amplification ◽  
Optical Signal ◽  
Plasmonic Coupling
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