Deracemization and the first CD spectrum of a 310-helical peptide made of achiral α-amino-isobutyric acid residues in a chiral membrane mimetic environment

2013 ◽  
Vol 49 (86) ◽  
pp. 10133 ◽  
Author(s):  
Francesca Ceccacci ◽  
Giovanna Mancini ◽  
Paola Rossi ◽  
Paolo Scrimin ◽  
Alessandro Sorrenti ◽  
...  
1987 ◽  
Vol 114 (4) ◽  
pp. 470-474 ◽  
Author(s):  
G. S. G. Spencer ◽  
D. J. Hill ◽  
G. J. Garssen ◽  
J. P. G. Williams

Abstract. The effects of somatostatin on the acute metabolic actions of insulin on newborn rat myoblasts in culture has been examined during monolayer culture. Somatostatin significantly inhibited the insulin-stimulated uptake of [3H]leucine and [3H]amino-isobutyric acid into myoblasts but had no effect on basal (unstimulated) uptake of these two substances. The lowest concentration of somatostatin to have a significant effect was 10 μg/l, and this was apparent in all the experiments undertaken. The inhibitory effect of somatostatin was seen at all effective concentrations of insulin used (0.3–1 U/l). These findings lend support to the concept of an endocrine role for somatostatin in vivo and suggest that a peripheral antagonism may exist between circulating insulin and somatostatin on anabolic processes such as nutrient uptake into cells.


1992 ◽  
Vol 15 (8) ◽  
pp. 1351-1360 ◽  
Author(s):  
B. L. Lee ◽  
S. C. Chua ◽  
H. Y. Ong ◽  
H. P. Lee ◽  
C. N. Ong

PEDIATRICS ◽  
1971 ◽  
Vol 48 (4) ◽  
pp. 636-639
Author(s):  
Joseph L. Potter ◽  
Arthur G. Weinberg ◽  
Raymond West

Four patients with ampicillinuria and ampicillin crystalluria have been reported. The presence of ampicillin leads to false positive spots for leucine/isoleucine, phenylalanine, and β-amino isobutyric acid in paper chromatograms of the urinary amino acids, and to a false-positive spot for phenylalanine in paper electrophoretograms. Crystalluria, due to ampicillin, is also described. Its significance remains to be determined.


2018 ◽  
Vol 105 (Special Issue) ◽  
Author(s):  
V. Rajeswari ◽  
P. Jeyakumar ◽  
M. K. Kalarani ◽  
K. S. Subramanian ◽  
M. Kavino

1963 ◽  
Vol 28 (1) ◽  
pp. 73-78 ◽  
Author(s):  
J. R. DANIELS ◽  
S. M. KALMAN

SUMMARY Adult Long Evans rats were ovariectomized and, one month later, were subjected to partial hepatectomy. Immature Long Evans rats were either partially hepatectomized in one step, or complete hepatectomy was accomplished by a two-stage operation which included ligation of the inferior vena cava followed by a partial evisceration. The response of these animals to injected oestradiol was compared with that of sham-operated controls by observing uptake of water by the uterus in vivo, and also by estimating the ability of surviving uterine fragments to accumulate radioactive α-amino-isobutyric acid in vitro. It was found that partial or complete hepatectomy did not abolish the response of the uterus to oestradiol. These results seem to exclude an essential role for the liver in the early response of a target organ to an oestrogenic hormone.


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