scholarly journals Walnut polyphenol metabolites, urolithins A and B, inhibit the expression of the prostate-specific antigen and the androgen receptor in prostate cancer cells

2014 ◽  
Vol 5 (11) ◽  
pp. 2922-2930 ◽  
Author(s):  
Claudia Sánchez-González ◽  
Carlos J. Ciudad ◽  
Véronique Noé ◽  
Maria Izquierdo-Pulido
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Cells ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Prostate Cancer Cells ◽  
Down Regulation

Urolithins attenuate the function of the AR by repressing its expression, causing a down-regulation of PSA levels and inducing apoptosis. Our results suggest that a diet rich in ellagitannins could contribute to the prevention of prostate cancer.

scholarly journals p300 Regulates Androgen Receptor–Independent Expression of Prostate-Specific Antigen in Prostate Cancer Cells Treated Chronically with Interleukin-6

2005 ◽  
Vol 65 (13) ◽  
pp. 5965-5973 ◽  
Author(s):  
Jose D. Debes ◽  
Barbara Comuzzi ◽  
Lucy J. Schmidt ◽  
Scott M. Dehm ◽  
Zoran Culig ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Cancer Cells ◽  
Prostate Specific Antigen ◽  
Interleukin 6 ◽  
Specific Antigen ◽  
Prostate Cancer Cells
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