Network pharmacology study on the mechanism of traditional Chinese medicine for upper respiratory tract infection

2014 ◽  
Vol 10 (10) ◽  
pp. 2517-2525 ◽  
Author(s):  
Xinzhuang Zhang ◽  
Jiangyong Gu ◽  
Liang Cao ◽  
Na Li ◽  
Yiming Ma ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Signaling Pathways ◽  
Network Pharmacology ◽  
Upper Respiratory Tract ◽  
Host Interaction ◽  
Upper Respiratory

The mechanism of RDN on URTIs is to inhibit virus–host interaction and to regulate signaling pathways by a combination of multi-target ingredients.

HERBAL FORMULATION (IMMUHELP) IN THE MANAGEMENT OF UPPER RESPIRATORY TRACT INFECTION.

2021 ◽  
pp. 10-19
Author(s):  
Yamini Bhusan Tripathi ◽  
Priyanka Mishra ◽  
Harsh Pandey ◽  
Priya Shree ◽  
Nikhil Pandey ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Animal Experiments ◽  
Upper Respiratory Tract Infection ◽  
Host Cells ◽  
Upper Respiratory Tract ◽  
Host Interaction ◽  
Upper Respiratory

The Upper respiratory tract infection is mainly attributed to viral infections so focus should be given to inhibition of viral-host interaction, their entry and replication in the host cells and release of inammatory st cytokines, resulting physiological disturbances. The host's immune system is the 1 line of defence against such threats so multitargeted herbal immune-boosters, with antioxidant, anti-inammatory and tissue repair potential would be preferred. The natural cocktail of medicinal plants has shown promising results both by using bioinformatics based drug docking studies, in animal experiments and in clinical trials. Here we have reviewed the 6-medicinal plants, used in making “Immuhelp”, towards their established role in management of viral-host interaction, activation of innate and adaptive immunity, inhibition-potential against release of inammatory cytokines, immunosuppressive and chemoattractant agents and antioxidant potentials.

Sign in / Sign up

Export Citation Format

Share Document