Nanostructure controlled sustained delivery of human growth hormone using injectable, biodegradable, pH/temperature responsive nanobiohybrid hydrogel

Nanoscale ◽  
2015 ◽  
Vol 7 (7) ◽  
pp. 3043-3054 ◽  
Author(s):  
Narendra K. Singh ◽  
Quang Vinh Nguyen ◽  
Bong Sup Kim ◽  
Doo Sung Lee
Keyword(s):  
Growth Hormone ◽  
Layered Double Hydroxide ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Temperature Sensitive ◽  
Sustained Delivery ◽  
Temperature Responsive ◽  
Hydrogel Matrix ◽  
Temperature Sensitive Hydrogel ◽  
Double Hydroxide

The combination of layered double hydroxide nanoclay particles and pH/temperature-sensitive hydrogel matrix effectively controlled the delivery of human growth hormone.

Controlled release of human growth hormone from a biodegradable pH/temperature-sensitive hydrogel system

Soft Matter ◽  
2011 ◽  
Vol 7 (19) ◽  
pp. 8984 ◽  
Author(s):  
Cong Truc Huynh ◽  
Seong Woo Kang ◽  
Yi Li ◽  
Bong Sup Kim ◽  
Doo Sung Lee
Keyword(s):  
Growth Hormone ◽  
Controlled Release ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Temperature Sensitive ◽  
Temperature Sensitive Hydrogel ◽  
Hydrogel System

Thiolated Glycol Chitosan Bearing α -Cyclodextrin for Sustained Delivery of PEGylated Human Growth Hormone

2012 ◽  
Vol 23 (15) ◽  
pp. 1995-2005 ◽  
Author(s):  
Maharajan Sivasubramanian ◽  
Yu-Jeong Kim ◽  
Su Young Chae ◽  
Sohee Son ◽  
Dong-Gyu Jo ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Sustained Delivery ◽  
Glycol Chitosan

Injectable and sustained delivery of human growth hormone using chemically modified Pluronic copolymer hydrogels

2008 ◽  
Vol 3 (5) ◽  
pp. 669-675 ◽  
Author(s):  
Sung Young Park ◽  
Hyun Jung Chung ◽  
Yuhan Lee ◽  
Tae Gwan Park
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Sustained Delivery ◽  
Chemically Modified

Sustained delivery of human growth hormone using a polyelectrolyte complex-loaded thermosensitive polyphosphazene hydrogel

2010 ◽  
Vol 147 (3) ◽  
pp. 359-367 ◽  
Author(s):  
Mi-Ran Park ◽  
ChangJu Chun ◽  
Sung-Won Ahn ◽  
Min-Hyo Ki ◽  
Chong-Su Cho ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Polyelectrolyte Complex ◽  
Human Growth ◽  
Sustained Delivery

Bioresorbable polypeptide-based comb-polymers efficiently improves the stability and pharmacokinetics of proteins in vivo

2017 ◽  
Vol 5 (4) ◽  
pp. 837-848 ◽  
Author(s):  
Md. Hasan Turabee ◽  
Thavasyappan Thambi ◽  
Jae Seung Lym ◽  
Doo Sung Lee
Keyword(s):  
Growth Hormone ◽  
Phase Transitions ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Sustained Delivery ◽  
Amphiphilic Copolymers ◽  
Comb Polymers ◽  
Gel Phase ◽  
The Stability

Polypeptide-based comb-like amphiphilic copolymers that exhibits sol-to-gel phase transitions in response to physiological pH and temperature have been developed for the sustained delivery of human growth hormone.

Sustained delivery of human growth hormone from a novel gel system: SABERTM

Biomaterials ◽  
2002 ◽  
Vol 23 (22) ◽  
pp. 4353-4358 ◽  
Author(s):  
Franklin W. Okumu ◽  
Le N. Dao ◽  
Paul J. Fielder ◽  
Noel Dybdal ◽  
Dennis Brooks ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Sustained Delivery ◽  
Gel System

Cyclodextrin-Based Nanocomplexes for Sustained Delivery of Human Growth Hormone

2013 ◽  
Vol 13 (11) ◽  
pp. 7306-7311 ◽  
Author(s):  
Maharajan Sivasubramanian ◽  
Joon-Youl Lee ◽  
Kap Jin Kim ◽  
Gurusamy Saravanakumar ◽  
Young Mo Kang ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Sustained Delivery
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