Efficient synthesis of zirconium poly(styrene-phenylvinylphosphonate)phosphate-supported proline as a recyclable catalyst for direct asymmetric aldol reactions in water

RSC Advances ◽  
2015 ◽  
Vol 5 (5) ◽  
pp. 3168-3176 ◽  
Author(s):  
Chuanlong Wu ◽  
Xiaoqin Long ◽  
Xiangkai Fu ◽  
Guangwei Wang ◽  
Zakaria. A. Mirza
Keyword(s):  
Large Scale ◽  
Recyclable Catalyst ◽  
Aldol Reactions ◽  
Efficient Synthesis ◽  
Asymmetric Aldol

A completely non-chromatographic and highly large-scale adaptable synthesis of zirconium poly(styrene-phenylvinylphosphonate)phosphate-supported l-proline (ZrPS-PVPA-Pr) has been developed in only three steps overall.

Alternating chiral selectivity of aldol reactions under the confined space of mesoporous silica

2015 ◽  
Vol 51 (96) ◽  
pp. 17116-17119 ◽  
Author(s):  
Chewei Yeh ◽  
Yan-Ru Sun ◽  
Shing-Jong Huang ◽  
Yeun-Min Tsai ◽  
Soofin Cheng
Keyword(s):  
Mesoporous Silica ◽  
Aldol Reaction ◽  
Recyclable Catalyst ◽  
Aldol Reactions ◽  
Water Medium ◽  
Confined Space ◽  
Asymmetric Aldol ◽  
Co Catalysts ◽  
Asymmetric Aldol Reaction ◽  
Chiral Selectivity

The chiral selectivities were altered and high diastereo- and enantio-selectivities of the products were obtained in water medium without adding acid co-catalysts when a primary–tertiary diamine catalyst was immobilized on mesoporous SBA-15 to form a recyclable catalyst for the direct asymmetric aldol reaction of cyclohexanone with p-nitrobenzaldehyde.

Hydrophobically Directed Aldol Reactions: Polystyrene-SupportedL-Proline as a Recyclable Catalyst for Direct Asymmetric Aldol Reactions in the Presence of Water (Eur. J. Org. Chem. 28/2007)

2007 ◽  
Vol 2007 (28) ◽  
pp. 4611-4611 ◽  
Author(s):  
Michelangelo Gruttadauria ◽  
Francesco Giacalone ◽  
Adriana Mossuto Marculescu ◽  
Paolo Lo Meo ◽  
Serena Riela ◽  
...  
Keyword(s):  
Recyclable Catalyst ◽  
Aldol Reactions ◽  
Asymmetric Aldol

scholarly journals Earthworms as a Biocatalyst: In Asymmetric Aldol Reactions

2017 ◽  
Vol 22 (9) ◽  
pp. 1162-1167
Author(s):  
Guo-Yan Zhang ◽  
Yan-Li Chen ◽  
Hai-Hong Li ◽  
Zhi Guan ◽  
Yan-Hong He
Keyword(s):  
Crude Extract ◽  
Industrial Production ◽  
Carbonyl Compounds ◽  
Large Scale ◽  
Environmentally Friendly ◽  
Aldol Reactions ◽  
Asymmetric Aldol ◽  
Excellent Yield ◽  
Wide Range ◽  
Potential Possibility

A crude extract from earthworms was used as an environmentally friendly and easily accessible biocatalyst for asymmetric direct aldol reactions. The β-hydroxy carbonyl compounds could be prepared in yields of up to 94%, with ee values of up to 98% and dr of up to >99:1. A wide range of substrates could participate in the reaction. This earthworm catalyst was also efficient in the large-scale reaction, providing product in excellent yield and good selectivity. The protocol as an example gives inspiration for the development of sustainable catalysts from nature, which also provides a potential possibility for application of earthworm catalyst in industrial production.

ChemInform Abstract: Hydrophobically Directed Aldol Reactions: Polystyrene-Supported L-Proline as a Recyclable Catalyst for Direct Asymmetric Aldol Reactions in the Presence of Water.

ChemInform ◽  
2008 ◽  
Vol 39 (5) ◽  
Author(s):  
Michelangelo Gruttadauria ◽  
Francesco Giacalone ◽  
Adriana Mossuto Marculescu ◽  
Paolo Lo Meo ◽  
Serena Riela ◽  
...  
Keyword(s):  
Recyclable Catalyst ◽  
Aldol Reactions ◽  
Asymmetric Aldol

ChemInform Abstract: The Application of a Structurally Simple, Recyclable, and Large-Scale L-Prolinamide Catalyst for Asymmetric Aldol Reactions.

ChemInform ◽  
2014 ◽  
Vol 45 (51) ◽  
pp. no-no
Author(s):  
Zhi Guan ◽  
Yuan Luo ◽  
Bao-Qiang Zhang ◽  
Krystal Heinen ◽  
Da-Cheng Yang ◽  
...  
Keyword(s):  
Large Scale ◽  
Aldol Reactions ◽  
Asymmetric Aldol

The application of a structurally simple, recyclable, and large-scale l-prolinamide catalyst for asymmetric aldol reactions

2014 ◽  
Vol 25 (10-11) ◽  
pp. 802-812 ◽  
Author(s):  
Zhi Guan ◽  
Yuan Luo ◽  
Bao-Qiang Zhang ◽  
Krystal Heinen ◽  
Da-Cheng Yang ◽  
...  
Keyword(s):  
Large Scale ◽  
Aldol Reactions ◽  
Asymmetric Aldol

Efficient synthesis of supported proline catalysts for asymmetric aldol reactions

2015 ◽  
Vol 5 (2) ◽  
pp. 690-696 ◽  
Author(s):  
A. A. Elmekawy ◽  
J. B. Sweeney ◽  
D. R. Brown
Keyword(s):  
High Activity ◽  
Aldol Reaction ◽  
Single Step ◽  
Aldol Reactions ◽  
Efficient Synthesis ◽  
Asymmetric Aldol ◽  
Mcm 41

l-Proline is grafted onto silica (MCM-41) in a single step and shows high activity and enantioselectivity in an aldol reaction.

scholarly journals Hydrophobically Directed Aldol Reactions: Polystyrene-SupportedL-Proline as a Recyclable Catalyst for Direct Asymmetric Aldol Reactions in the Presence of Water

2007 ◽  
Vol 2007 (28) ◽  
pp. 4688-4698 ◽  
Author(s):  
Michelangelo Gruttadauria ◽  
Francesco Giacalone ◽  
Adriana Mossuto Marculescu ◽  
Paolo Lo Meo ◽  
Serena Riela ◽  
...  
Keyword(s):  
Recyclable Catalyst ◽  
Aldol Reactions ◽  
Asymmetric Aldol

(S)-5-prolylamide-triazole Organocatalyst for Direct Asymmetric Aldol Reactions

2013 ◽  
Vol 17 (14) ◽  
pp. 1563-1568 ◽  
Author(s):  
Ling Liu ◽  
Min-Na Gao ◽  
Yang Li ◽  
Zhen Li ◽  
Liping Song ◽  
...  
Keyword(s):  
Aldol Reactions ◽  
Asymmetric Aldol
Sign in / Sign up

Export Citation Format

Share Document