High-precision isotopic analysis of Cu in blood serum via multi-collector ICP-mass spectrometry for clinical investigation: steps towards improved robustness and higher sample throughput

2017 ◽  
Vol 32 (3) ◽  
pp. 597-608 ◽  
Author(s):  
Sara Lauwens ◽  
Marta Costas-Rodríguez ◽  
Hans Van Vlierberghe ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
Isotopic Composition ◽  
Blood Serum ◽  
Diurnal Variation ◽  
Clinical Investigation ◽  
Isotopic Analysis ◽  
Clinical Context ◽  
Sample Throughput ◽  
Icp Ms ◽  
Icp Mass Spectrometry

A procedure for Cu isolation from serum prior to MC-ICP-MS measurements was developed and applied in a clinical context. The serum Cu isotopic composition does not show diurnal variation.

Isotopic analysis of Cu in blood serum by multi-collector ICP-mass spectrometry: a new approach for the diagnosis and prognosis of liver cirrhosis?

Metallomics ◽  
2015 ◽  
Vol 7 (3) ◽  
pp. 491-498 ◽  
Author(s):  
Marta Costas-Rodríguez ◽  
Yulia Anoshkina ◽  
Sara Lauwens ◽  
Hans Van Vlierberghe ◽  
Joris Delanghe ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liver Cirrhosis ◽  
Isotopic Composition ◽  
Blood Serum ◽  
Isotopic Analysis ◽  
Potential Parameter ◽  
New Approach ◽  
Diagnosis And Prognosis ◽  
Prognosis Of Liver Cirrhosis ◽  
Icp Mass Spectrometry

The isotopic composition of blood serum Cu has been investigated as a potential parameter for the diagnosis and prognosis of liver cirrhosis.

A new practical isobaric interference correction model for the in situ Hf isotopic analysis using laser ablation-multi-collector-ICP-mass spectrometry of zircons with high Yb/Hf ratios

2019 ◽  
Vol 34 (6) ◽  
pp. 1223-1232 ◽  
Author(s):  
Hai-Ou Gu ◽  
He Sun ◽  
Fangyue Wang ◽  
Can Ge ◽  
Taofa Zhou
Keyword(s):  
Mass Spectrometry ◽  
Laser Ablation ◽  
Isotopic Analysis ◽  
Correction Model ◽  
Isobaric Interference ◽  
Interference Correction ◽  
Icp Ms ◽  
Icp Mass Spectrometry

An isobaric interference correction model was proposed for the in situ Hf isotopic analysis of zircons with high Yb/Hf ratios using LA-MC-ICP-MS.

Single-step chromatographic isolation of lithium from whole-rock carbonate and clay for isotopic analysis with multi-collector ICP-mass spectrometry

2015 ◽  
Vol 30 (12) ◽  
pp. 2533-2540 ◽  
Author(s):  
K. Van Hoecke ◽  
J. Belza ◽  
T. Croymans ◽  
S. Misra ◽  
P. Claeys ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Isotope Ratio ◽  
Isotopic Analysis ◽  
Single Step ◽  
Clay Material ◽  
Icp Ms ◽  
Chromatographic Procedure ◽  
Ratio Determination ◽  
Icp Mass Spectrometry ◽  
Chromatographic Isolation

An ion chromatographic procedure allows isolation of lithium from carbonate and clay material prior to isotope ratio determination with MC-ICP-MS.

scholarly journals Direct lead isotopic analysis of bioethanol by means of multi-collector ICP-mass spectrometry with a total consumption sample introduction system

2018 ◽  
Vol 33 (3) ◽  
pp. 481-490 ◽  
Author(s):  
Carlos Sánchez ◽  
Eduardo Bolea-Fernandez ◽  
Marta Costas-Rodríguez ◽  
Charles-Philippe Lienemann ◽  
Jose-Luis Todolí ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sample Pretreatment ◽  
Isotopic Analysis ◽  
Sample Introduction ◽  
Target Element ◽  
Total Consumption ◽  
Sample Matrix ◽  
System P ◽  
Icp Ms ◽  
Icp Mass Spectrometry

A method has been developed for the direct (no sample pretreatment and/or isolation of the target element from the sample matrix) Pb isotopic analysis of bioethanol via multi-collector ICP-mass spectrometry (MC-ICP-MS).

scholarly journals Lead isotopic analysis of Antarctic snow using multi-collector ICP-mass spectrometry

2015 ◽  
Vol 30 (6) ◽  
pp. 1322-1328 ◽  
Author(s):  
Andrea Bazzano ◽  
Kris Latruwe ◽  
Marco Grotti ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
Concentration Level ◽  
Isotopic Analysis ◽  
Sample Introduction ◽  
Total Consumption ◽  
Sample Introduction System ◽  
Icp Ms ◽  
Antarctic Snow ◽  
Icp Mass Spectrometry

Precise and accurate lead isotopic analysis of Antarctic snow at the pg g−1 concentration level has been achieved by combining a total consumption sample introduction system with MC-ICP-MS.

Laser ablation-tandem ICP-mass spectrometry (LA-ICP-MS/MS) for direct Sr isotopic analysis of solid samples with high Rb/Sr ratios

2016 ◽  
Vol 31 (2) ◽  
pp. 464-472 ◽  
Author(s):  
Eduardo Bolea-Fernandez ◽  
Stijn J. M. Van Malderen ◽  
Lieve Balcaen ◽  
Martín Resano ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
Laser Ablation ◽  
Isotopic Analysis ◽  
Solid Samples ◽  
Icp Ms ◽  
Icp Mass Spectrometry

The combination of laser ablation and tandem ICP-mass spectrometry (LA-ICP-MS/MS) allows for successful Sr isotopic analysis of solid samples with high Rb/Sr ratios.

Evaluation of the use of cold plasma conditions for Fe isotopic analysis via multi-collector ICP-mass spectrometry: effect on spectral interferences and instrumental mass discrimination

2017 ◽  
Vol 32 (3) ◽  
pp. 538-547 ◽  
Author(s):  
Stepan M. Chernonozhkin ◽  
Marta Costas-Rodríguez ◽  
Philippe Claeys ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
Cold Plasma ◽  
Isotopic Analysis ◽  
Mass Discrimination ◽  
Spectral Interferences ◽  
Icp Ms ◽  
Icp Mass Spectrometry

The application of cold plasma conditions for isotopic analysis of Fe via MC-ICP-MS was evaluated in combination with the standard and the ‘jet’ interface and with dry and wet plasma conditions.

Determination of the isotopic composition of sub-ng amounts of Sr in Antarctic snow by multi-collector ICP-mass spectrometry

2017 ◽  
Vol 32 (5) ◽  
pp. 1004-1008 ◽  
Author(s):  
Andrea Bazzano ◽  
Kris Latruwe ◽  
Marco Grotti ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
Isotopic Composition ◽  
Isotope Ratio ◽  
Sr Isotope ◽  
Atmospheric Particulates ◽  
Icp Ms ◽  
Antarctic Snow ◽  
Ancient Times ◽  
Icp Mass Spectrometry

Determination of the87Sr/86Sr isotope ratio in Antarctic snow by multi-collector ICP-MS can provide useful information on the sources of the atmospheric particulates in present and ancient times.

Tandem ICP-mass spectrometry for Sr isotopic analysis without prior Rb/Sr separation

2016 ◽  
Vol 31 (1) ◽  
pp. 303-310 ◽  
Author(s):  
Eduardo Bolea-Fernandez ◽  
Lieve Balcaen ◽  
Martín Resano ◽  
Frank Vanhaecke
Keyword(s):  
Mass Spectrometry ◽  
Isotope Ratio ◽  
Accurate Determination ◽  
Isotopic Analysis ◽  
Mass Discrimination ◽  
Sr Isotope ◽  
Geological Materials ◽  
Icp Ms ◽  
Icp Mass Spectrometry

The use of CH3F as a reaction gas in tandem ICP-mass spectrometry (ICP-MS/MS) enables the accurate determination of the 87Sr/86Sr isotope ratio in geological materials, provided that mass discrimination is corrected for by a combination of internal and external correction.

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