Synthesis, decoration, and cellular effects of magnetic mesoporous silica nanoparticles

RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57275-57283 ◽  
Author(s):  
J. L. Nyalosaso ◽  
E. Rascol ◽  
C. Pisani ◽  
C. Dorandeu ◽  
X. Dumail ◽  
...  

Synthesis of magnetic core@shell nanoparticles with different coatings and the study of their uptake by cells.

2012 ◽  
Vol 11 (06) ◽  
pp. 1240031 ◽  
Author(s):  
FENG LIU ◽  
HUA TIAN ◽  
JUNHUI HE ◽  
HONGYING LIU

In this paper, magnetic mesoporous silica nanoparticles ( Fe 3 O 4–n SiO 2–m SiO 2) were synthesized using trimethylbenzene (TMB) as a swelling agent. These composite nanoparticles have a typical sandwich structure with a magnetic core, a nonporous silica middle layer and an ordered mesoporous silica outer shell. The experimental results indicate that the magnetic mesoporous silica nanoparticles have high specific surface area (510 m2/g), large pore size (3.8 nm) and pore volume (1.04 cm3/g). The thickness and pore structure of the out shell can also be easily tailored by adjusting the reaction conditions. The obtained nanomaterials were characterized by X-ray diffraction, transmission electron microscopy and nitrogen adsorption–desorption measurements.


2017 ◽  
Vol 41 (24) ◽  
pp. 15334-15346 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Bharathiraja Subramanian ◽  
Manivasagan Panchanathan ◽  
Sudip Mondal ◽  
Hyehyun Kim ◽  
...  

Fucoidan-coated FeNP@SiOH@Fuc NPs have been proposed for chemotherapy and thermal therapy applications in emerging cancer therapy.


2016 ◽  
Vol 16 (4) ◽  
pp. 4195-4199 ◽  
Author(s):  
Nikola Ž Knežević

Drug (9-aminoacridine) loaded core/shell magnetic iron oxide-containing mesoporous silica nanoparticles (MMSN) were treated with HeLa cells and the drug carriers were agitated by exposure to magnetic field. Viability studies show the applicability of drug loaded magnetic material for anticancer treatment, which is enhanced upon stimulation with magnetic field. Confocal micrographs of fluorescein grafted MMSN-treated HeLa cells confirmed the ability of magnetic field to concentrate the synthesized material in the exposed area of the cells. The synthesized material and the applied drug delivery method may find application in magnetic field-responsive targeted treatment of cancer.


2018 ◽  
Vol 215 (19) ◽  
pp. 1800266 ◽  
Author(s):  
David Patiño-Ruiz ◽  
Lina Sanchez-Botero ◽  
Juan Hinestroza ◽  
Adriana Herrera

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