A lysosome-targeted and ratiometric fluorescent probe for imaging exogenous and endogenous hypochlorous acid in living cells

2016 ◽  
Vol 4 (27) ◽  
pp. 4739-4745 ◽  
Author(s):  
Mingguang Ren ◽  
Beibei Deng ◽  
Kai Zhou ◽  
Xiuqi Kong ◽  
Jian-Yong Wang ◽  
...  

We have developed the first small-molecule based, lysosomal-targeted ratiometric fluorescent HClO probe (Lyso-HA). Fluorescence imaging shows that it is suitable for ratiometric visualization of exogenous and endogenous HClO at lysosomes in living cells.

2019 ◽  
Vol 43 (2) ◽  
pp. 552-555 ◽  
Author(s):  
Li Wang ◽  
Mingguang Ren ◽  
Zihong Li ◽  
Lixuan Dai ◽  
Weiying Lin

We have developed a new small-molecule based, mitochondrial-targeted ratiometric fluorescent palladium(ii) probe (CR-Pd). Fluorescence imaging shows that CR-Pd is suitable for the ratiometric visualization of palladium(ii) in living cells.


2017 ◽  
Vol 41 (13) ◽  
pp. 5259-5262 ◽  
Author(s):  
Mingguang Ren ◽  
Jing Nie ◽  
Beibei Deng ◽  
Kai Zhou ◽  
Jian-Yong Wang ◽  
...  

We have developed a new small-molecule based lysosome-targeted ratiometric fluorescent HOCl probe (FL-HA). Fluorescence imaging shows that FL-HA is suitable for ratiometric visualization of HOCl within lysosomes in living cells.


2017 ◽  
Vol 247 ◽  
pp. 736-741 ◽  
Author(s):  
Qiong Yuan ◽  
Zhi-Min Zhao ◽  
Yan-Ru Zhang ◽  
Le Su ◽  
Jun-Ying Miao ◽  
...  

2020 ◽  
Vol 44 (42) ◽  
pp. 18389-18398
Author(s):  
Qiujuan Ma ◽  
Chunyan Wang ◽  
Guojiang Mao ◽  
Meiju Tian ◽  
Jingguo Sun ◽  
...  

A novel reticulum-targeting and ratiometric fluorescent probe for determining hypochlorous acid has been developed.


2015 ◽  
Vol 39 (11) ◽  
pp. 8940-8947 ◽  
Author(s):  
Sima Paul ◽  
Shyamaprosad Goswami ◽  
Chitrangada Das Mukhopadhyay

A ratiometric fluorescent probe having a fast response and a large Stokes shift detects SH− both in solid and vapour phases and this probe is used for fluorescence imaging of SH− in living cells.


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