Chiral reagents in glycosylation and modification of carbohydrates

2018 ◽  
Vol 47 (3) ◽  
pp. 681-701 ◽  
Author(s):  
Hao-Yuan Wang ◽  
Stephanie A. Blaszczyk ◽  
Guozhi Xiao ◽  
Weiping Tang
Keyword(s):  
Chiral Auxiliaries ◽  
Chiral Catalysts ◽  
Stereoselective Glycosylation ◽  
Selective Functionalization ◽  
Recent Advances ◽  
Site Selective

This review summarizes recent advances in stereoselective glycosylation and site-selective functionalization of carbohydrates mediated by chiral reagents including chiral auxiliaries and chiral catalysts.

scholarly journals Recent advances in site-selective functionalization of carbohydrates mediated by organocatalysts

2019 ◽  
Vol 471 ◽  
pp. 64-77 ◽  
Author(s):  
Stephanie A. Blaszczyk ◽  
Timothy C. Homan ◽  
Weiping Tang
Keyword(s):  
Selective Functionalization ◽  
Recent Advances ◽  
Site Selective

scholarly journals Site-selective functionalization of remote aliphatic C–H bonds via C–H metallation

2021 ◽  
Author(s):  
Qi Zhang ◽  
Bing-Feng Shi
Keyword(s):  
Selective Functionalization ◽  
Recent Advances ◽  
Site Selective

Recent advances in site-selective functionalization of remote aliphatic C–H bonds in organometallic pathways are summarized.

para-Selective Cyanation of Arenes by H-Bonded Template

2019 ◽  
Author(s):  
Sandeep Pimparkar ◽  
Trisha Bhattacharya ◽  
Arun Maji ◽  
Argha Saha ◽  
Ramasamy Jayarajan ◽  
...  
Keyword(s):  
Selective Functionalization ◽  
Directing Group ◽  
Product Utility ◽  
Site Selective

The significance of site selective functionalization stands upon the superior selectivity, easy synthesis and diverse product utility. In this work we demonstrate the <i>para</i>-selective introduction of versatile nitrile moiety, enabled by detachable and reusable H-bonded auxiliary. The methodology holds its efficiency irrespective of substrate electronic bias. The conspicuous shift in the step energetics was probed by both experimental and computational mechanistic tools heralds the inception of <i>para</i>-deuteration. The synthetic impact of the methodology was highlighted with reusability of directing group and post synthetic modifications

para-Selective Cyanation of Arenes by H-Bonded Template

2019 ◽  
Author(s):  
Sandeep Pimparkar ◽  
Trisha Bhattacharya ◽  
Arun Maji ◽  
Argha Saha ◽  
Ramasamy Jayarajan ◽  
...  
Keyword(s):  
Selective Functionalization ◽  
Directing Group ◽  
Product Utility ◽  
Site Selective

The significance of site selective functionalization stands upon the superior selectivity, easy synthesis and diverse product utility. In this work we demonstrate the <i>para</i>-selective introduction of versatile nitrile moiety, enabled by detachable and reusable H-bonded auxiliary. The methodology holds its efficiency irrespective of substrate electronic bias. The conspicuous shift in the step energetics was probed by both experimental and computational mechanistic tools heralds the inception of <i>para</i>-deuteration. The synthetic impact of the methodology was highlighted with reusability of directing group and post synthetic modifications

Recent Advances in C–Br Bond Formation

Synlett ◽  
2021 ◽  
Author(s):  
Ying-Yeung Yeung ◽  
Jonathan Wong
Keyword(s):  
Organic Synthesis ◽  
Aromatic Compounds ◽  
Bond Formation ◽  
Cross Coupling ◽  
Catalytic Site ◽  
Atom Transfer ◽  
Bond Forming ◽  
Recent Advances ◽  
Catalytic Asymmetric ◽  
Site Selective

AbstractOrganobromine compounds are extremely useful in organic synthesis. In this perspective, a focused discussion on some recent advancements in C–Br bond-forming reactions is presented.1 Introduction2 Selected Recent Advances2.1 Catalytic Asymmetric Bromopolycyclization of Olefinic Substrates2.2 Catalytic Asymmetric Intermolecular Bromination2.3 Some New Catalysts and Reagents for Bromination2.4 Catalytic Site-Selective Bromination of Aromatic Compounds2.5 sp3 C–H Bromination via Atom Transfer/Cross-Coupling3 Outlook

Stereoselective Glycosylation Reactions with Chiral Auxiliaries

2005 ◽  
Vol 44 (6) ◽  
pp. 947-949 ◽  
Author(s):  
Jin-Hwan Kim ◽  
Hai Yang ◽  
Geert-Jan Boons
Keyword(s):  
Chiral Auxiliaries ◽  
Stereoselective Glycosylation

scholarly journals A lesson for site-selective C–H functionalization on 2-pyridones: radical, organometallic, directing group and steric controls

2018 ◽  
Vol 9 (1) ◽  
pp. 22-32 ◽  
Author(s):  
Koji Hirano ◽  
Masahiro Miura
Keyword(s):  
Pharmaceutical Chemistry ◽  
Recent Advances ◽  
Directing Group ◽  
Site Selective

This minireview focuses on recent advances in site-selective C–H functionalization on 2-pyridone which is an important heterocyclic motif in medicinal and pharmaceutical chemistry.

Sign in / Sign up

Export Citation Format

Share Document