scholarly journals Small molecule piperazinyl-benzimidazole antagonists of the gonadotropin-releasing hormone (GnRH) receptor

MedChemComm ◽  
2017 ◽  
Vol 8 (10) ◽  
pp. 1965-1969 ◽  
Author(s):  
Richard Fjellaksel ◽  
Marc Boomgaren ◽  
Rune Sundset ◽  
Ira H. Haraldsen ◽  
Jørn H. Hansen ◽  
...  

In this communication, we report the synthesis and characterization of a library of small molecule antagonists of the human gonadotropin releasing hormone receptor based upon the 2-(4-tert-butylphenyl)-4-piperazinyl-benzimidazole scaffold via Cu-catalysed azide alkyne cycloaddition.

2019 ◽  
Vol 208 ◽  
pp. 106109
Author(s):  
Adamu Mani Isa ◽  
Martha N. Bemji ◽  
Mathew Wheto ◽  
Tolulope J. Williams ◽  
Eveline M. Ibeagha-Awemu

Endocrinology ◽  
1999 ◽  
Vol 140 (2) ◽  
pp. 950-957 ◽  
Author(s):  
Scott Nelson ◽  
Regina D. Horvat ◽  
Jennifer Malvey ◽  
Deborah A. Roess ◽  
B. George Barisas ◽  
...  

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