A new approach to the stereoselective synthesis of trans-3-carbamoyl-β-lactam moieties
Optically active 1,4-disubstituted-3-carbamoyl-azetidinones are synthesized from 5-[(N-arylamino)(hydroxyl)methylene]-2,2-dimethyl-1,3-dioxa-4,6-diones and chiral aldimines via thermal generation of carbamoyl ketenes and subsequent [2+2] cycloaddition.
1998 ◽
Vol 63
(8)
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pp. 1187-1201
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2012 ◽
Vol 23
(9)
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pp. 662-669
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1999 ◽
Vol 63
(9)
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pp. 1605-1613
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2004 ◽
Vol 15
(6)
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pp. 941-949
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1992 ◽
Vol 33
(49)
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pp. 7575-7578
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