Mechanistic investigation of a Ru-catalyzed direct asymmetric reductive amination reaction for a batch or continuous process scale-up: an industrial perspective

2017 ◽  
Vol 2 (5) ◽  
pp. 720-739 ◽  
Author(s):  
Shujauddin M. Changi ◽  
Tohru Yokozawa ◽  
Tetsuya Yamamoto ◽  
Hikaru Nakajima ◽  
Matthew C. Embry ◽  
...  
Keyword(s):  
Reductive Amination ◽  
Continuous Process ◽  
Scale Up ◽  
Process Step ◽  
Model Driven ◽  
Amination Reaction ◽  
Mechanistic Investigation ◽  
Process Scale Up ◽  
Process Scale ◽  
Model Driven Approach

Scale-up of a pharmaceutical process step via an experimental and model driven approach.

Process Scale-up for Mercuric-5-Nitrotetrazole

1976 ◽  
Author(s):  
Robert E. Farncomb ◽  
Marguerite Chang ◽  
Frank J. Pisacane
Keyword(s):  
Scale Up ◽  
Process Scale Up ◽  
Process Scale

A Forward-Looking Approach to Process Scale-Up for Solid Dose Manufacturing

2008 ◽  
pp. 119-152 ◽  
Author(s):  
Fernando Muzzio ◽  
Marianthi Ierapetritou ◽  
Patricia Portillo ◽  
Marcos Llusa ◽  
Michael Levin ◽  
...  
Keyword(s):  
Scale Up ◽  
Solid Dose ◽  
Process Scale Up ◽  
Process Scale ◽  
Forward Looking
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