scholarly journals Copper(ii) complexes based on quinoline-derived Schiff-base ligands: synthesis, characterization, HSA/DNA binding ability, and anticancer activity

MedChemComm ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. 1663-1672 ◽  
Author(s):  
Kun Hu ◽  
Chensi Liu ◽  
Jingui Li ◽  
Fupei Liang
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Tumor Cell ◽  
Anticancer Activity ◽  
Hela Cells ◽  
Cell Apoptosis ◽  
Schiff Base Ligands ◽  
Binding Ability ◽  
Tumor Cell Apoptosis ◽  
Cell Cycles

Three Cu(ii) complexes (C1–C3) were designed and synthesized.C3, in particular, having a ligand derived from benzocaine, exhibited greater selectivity toward HeLa cells, arrested cell cycles, and promoted tumor cell apoptosis.

scholarly journals Overexpression of dominant negative PARP interferes with tumor formation of HeLa cells in nude mice: Evidence for increased tumor cell apoptosis in vivo

Oncogene ◽  
1999 ◽  
Vol 18 (50) ◽  
pp. 7010-7015 ◽  
Author(s):  
Margrit-Airin Hans ◽  
Marcus Müller ◽  
Mirella Meyer-Ficca ◽  
Alexander Bürkle ◽  
Jan-Heiner Küpper
Keyword(s):  
Tumor Cell ◽  
Nude Mice ◽  
Hela Cells ◽  
Cell Apoptosis ◽  
Tumor Formation ◽  
Dominant Negative ◽  
Tumor Cell Apoptosis

Mechanism of TRAIL Induced Tumor Cell Apoptosis and Application of TRAIL Based on Tumor Therapy

2012 ◽  
Vol 28 (6) ◽  
pp. 448 ◽  
Author(s):  
Ling ZHU ◽  
Xiangxi WANG ◽  
Xuemei LI ◽  
Jinliang YANG
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Tumor Therapy ◽  
Tumor Cell Apoptosis

scholarly journals Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking

RSC Advances ◽  
2021 ◽  
Vol 11 (38) ◽  
pp. 23310-23329
Author(s):  
Viviana Cuartas ◽  
Alberto Aragón-Muriel ◽  
Yamil Liscano ◽  
Dorian Polo-Cerón ◽  
Maria del Pilar Crespo-Ortiz ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Tumor Cell ◽  
Anticancer Activity ◽  
Cell Lines ◽  
Human Tumor ◽  
Tumor Cell Lines ◽  
Human Tumor Cell ◽  
Human Tumor Cell Lines

A new series of quinazoline-based chalcones and pyrimidodiazepines were tested against 60 human tumor cell lines.

Copper(II) complexes with tridentate halogen‐substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving group and ligand flexibility on antiproliferative activities

2021 ◽  
Author(s):  
Nazanin Kordestani ◽  
Hadi Amiri Rudbari ◽  
Alexandra R Fernandes ◽  
Luís R Raposo ◽  
André Luz ◽  
...  
Keyword(s):  
Schiff Base ◽  
Anticancer Activity ◽  
Crystal Structures ◽  
Copper Complexes ◽  
Schiff Base Ligands ◽  
Leaving Group ◽  
Leaving Groups ◽  
Tridentate Schiff Base ◽  
Antiproliferative Activities

To investigate the effect of different halogen substituents, leaving groups and the flexibility of ligand on the anticancer activity of copper complexes, sixteen copper(II) complexes with eight different tridentate Schiff-base...

scholarly journals Hsp60 Regulation of Tumor Cell Apoptosis

2007 ◽  
Vol 283 (8) ◽  
pp. 5188-5194 ◽  
Author(s):  
Jagadish C. Ghosh ◽  
Takehiko Dohi ◽  
Byoung Heon Kang ◽  
Dario C. Altieri
Keyword(s):  
Tumor Cell ◽  
Cell Apoptosis ◽  
Tumor Cell Apoptosis
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