Construction of trifluoromethylated quaternary stereocenters via p-quinone methides

2020 ◽  
Vol 56 (20) ◽  
pp. 3031-3034 ◽  
Author(s):  
Kyu Terashima ◽  
Tomoko Kawasaki-Takasuka ◽  
Tomohiro Agou ◽  
Toshio Kubota ◽  
Takashi Yamazaki
Keyword(s):  
Synthetic Method ◽  
Quinone Methides ◽  
Quaternary Centers ◽  
Quaternary Stereocenters

Development of a new synthetic method for the construction of quaternary centers with a CF3 group was realized by way of 1,6-addition of various nucleophiles to highly reactive δ-trifluoromethylated p-quinone methides generated in situ.

Gold-catalyzed construction of two adjacent quaternary stereocenters via sequential C–H functionalization and aldol annulation

2016 ◽  
Vol 52 (11) ◽  
pp. 2257-2260 ◽  
Author(s):  
Zhunzhun Yu ◽  
Haile Qiu ◽  
Lu Liu ◽  
Junliang Zhang
Keyword(s):  
Quaternary Centers ◽  
Aldol Cyclization ◽  
Quaternary Stereocenters

A novel gold-catalyzed intermolecular C–H functionalization and aldol cyclization for the construction of two adjacent quaternary centers is presented.

Lewis acid-catalyzed tandem cyclization of in situ generated o-quinone methides and arylsulfonyl hydrazides for a one-pot entry to 3-sulfonylbenzofurans

2019 ◽  
Vol 6 (24) ◽  
pp. 3929-3933 ◽  
Author(s):  
Fan-Xiao Meng ◽  
Ruo-Nan Wang ◽  
Hong-Li Huang ◽  
Shu-Wen Gong ◽  
Qian-Li Li ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Quinone Methides ◽  
One Pot ◽  
Acid Catalyzed ◽  
Tandem Cyclization ◽  
First Time

Lewis acid-mediated one-pot tandem cyclization of o-QMs with arylsulfonyl hydrazides was described for the first time and the corresponding 3-sulfonylbenzofuran products were obtained in moderate to good yields.

scholarly journals Asymmetric Synthesis of 2,3-Dihydrobenzofurans by a [4+1] Annulation Between Ammonium Ylides and In Situ Generated o -Quinone Methides

2017 ◽  
Vol 23 (21) ◽  
pp. 5137-5142 ◽  
Author(s):  
Nicole Meisinger ◽  
Lukas Roiser ◽  
Uwe Monkowius ◽  
Markus Himmelsbach ◽  
Raphaël Robiette ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Quinone Methides

scholarly journals Correction: An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface

2019 ◽  
Vol 55 (64) ◽  
pp. 9567-9567
Author(s):  
Xianghui Liu ◽  
Kai Wang ◽  
Wengang Guo ◽  
Yan Liu ◽  
Can Li
Keyword(s):  
Organic Base ◽  
Quinone Methides

Correction for ‘An organic-base catalyzed asymmetric 1,4-addition of tritylthiol to in situ generated aza-o-quinone methides at the H2O/DCM interface’ by Xianghui Liu et al., Chem. Commun., 2019, 55, 2668–2671.

Synthesis of 4-styrylcoumarins via FeCl3-promoted cascade reactions of propargylamines with β-keto esters

2019 ◽  
Vol 17 (16) ◽  
pp. 4005-4013 ◽  
Author(s):  
Li-Qin Yan ◽  
Xiaoting Cai ◽  
Xinwei He ◽  
Hui Wang ◽  
Mengqing Xie ◽  
...  
Keyword(s):  
Cascade Reactions ◽  
Cyclization Reaction ◽  
Quinone Methides ◽  
Keto Esters ◽  
Tandem Cyclization

A versatile and highly regioselective FeCl3-promoted tandem cyclization reaction of in situ generated alkynyl o-quinone methides (o-AQMs) with β-keto esters has been developed.

Development of sulfide reference materials for in situ platinum group elements and S–Pb isotope analyses by LA-(MC)-ICP-MS

2018 ◽  
Vol 33 (12) ◽  
pp. 2172-2183 ◽  
Author(s):  
Yantong Feng ◽  
Wen Zhang ◽  
Zhaochu Hu ◽  
Yongsheng Liu ◽  
Kang Chen ◽  
...  
Keyword(s):  
Hydrothermal Synthesis ◽  
Reference Materials ◽  
Platinum Group Elements ◽  
Pb Isotopes ◽  
Synthetic Method ◽  
Pb Isotope ◽  
Icp Ms ◽  
Platinum Group ◽  
Isotope Analyses

A new synthetic method has been used to prepare sulfide reference materials for the in situ analysis of PGEs and S–Pb isotopes. The results indicate that the hydrothermal synthesis of the nanoparticles can serve as a potentially effective approach for the preparation of microanalysis reference materials.

ChemInform Abstract: Catalytic Asymmetric Addition of Meldrum′s Acid, Malononitrile, and 1,3-Dicarbonyls to ortho-Quinone Methides Generated in situ under Basic Conditions.

ChemInform ◽  
2015 ◽  
Vol 46 (35) ◽  
pp. no-no
Author(s):  
Lorenzo Caruana ◽  
Martina Mondatori ◽  
Vasco Corti ◽  
Sara Morales ◽  
Andrea Mazzanti ◽  
...  
Keyword(s):  
Quinone Methides ◽  
Asymmetric Addition ◽  
Catalytic Asymmetric

Bifunctional tertiary amine-squaramide catalyzed asymmetric catalytic 1,6-conjugate addition/aromatization of para-quinone methides with oxindoles

2016 ◽  
Vol 52 (22) ◽  
pp. 4183-4186 ◽  
Author(s):  
Yu-Hua Deng ◽  
Xiang-Zhi Zhang ◽  
Ke-Yin Yu ◽  
Xu Yan ◽  
Ji-Yuan Du ◽  
...  
Keyword(s):  
Tertiary Amine ◽  
Conjugate Addition ◽  
Quinone Methides ◽  
Asymmetric Catalytic ◽  
Quaternary Stereocenters

A novel organocatalytic enantioselective 1,6-addition of p-QMs has been developed to access diarylmethine-functionalized oxindoles bearing vicinal tertiary and quaternary stereocenters.

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