An efficient synthesis of fluoro-neplanocin A analogs using electrophilic fluorination and palladium-catalyzed dehydrosilylation

2019 ◽  
Vol 6 (7) ◽  
pp. 959-966 ◽  
Author(s):  
Dnyandev B. Jarhad ◽  
Min Hwan Jang ◽  
Young Sup Shin ◽  
Gyudong Kim ◽  
Hong-Rae Kim ◽  
...  
Keyword(s):  
Efficient Synthesis ◽  
Efficient Approach ◽  
Neplanocin A ◽  
Electrophilic Fluorination ◽  
Palladium Catalyzed

An alternative and efficient approach to neplanocin A analogs 1b and 1d has been developed using electrophilic fluorination and Pd-catalyzed dehydrosilylation.

Palladium-catalyzed geometrically selective hydrogenation of (Z)-trifluoromethyl alkenyl triflate: an efficient approach to (Z) or (E)-3,3,3-trifluoropropenyl derivatives

2017 ◽  
Vol 15 (27) ◽  
pp. 5693-5700 ◽  
Author(s):  
Yilong Zhao ◽  
Yuhan Zhou ◽  
Chunxia Zhang ◽  
Huan Wang ◽  
Jinfeng Zhao ◽  
...  
Keyword(s):  
Selective Hydrogenation ◽  
Geometric Control ◽  
Efficient Approach ◽  
Palladium Catalyzed

Synthesis of (Z)- or (E)-3,3,3-trifluoropropenyl derivatives with excellent divergent geometric control via hydrogenation of (Z)-trifluoromethyl alkenyl triflates.

Palladium-Catalyzed Domino CH/NH Functionalization: An Efficient Approach to Nitrogen-Bridged Heteroacenes

2015 ◽  
Vol 21 (22) ◽  
pp. 8257-8261 ◽  
Author(s):  
Natsuyo Kamimoto ◽  
Dieter Schollmeyer ◽  
Koichi Mitsudo ◽  
Seiji Suga ◽  
Siegfried R. Waldvogel
Keyword(s):  
Efficient Approach ◽  
Palladium Catalyzed

Palladium-catalyzed highly regioselective 2-arylation of 2,x-dibromopyridines and its application in the efficient synthesis of a 17β-HSD1 inhibitor

Tetrahedron ◽  
2013 ◽  
Vol 69 (51) ◽  
pp. 10996-11003 ◽  
Author(s):  
Qizhong Zhou ◽  
Bin Zhang ◽  
Liangjun Su ◽  
Tiansheng Jiang ◽  
Rener Chen ◽  
...  
Keyword(s):  
Efficient Synthesis ◽  
Palladium Catalyzed

DABCO-Promoted [3+2] annulation for Efficient Synthesis of 1,2,5-Triaryl-1H-imidazoles from Substituted β-Nitrostyrenes and N-Arylbenzimidamides

Synthesis ◽  
2021 ◽  
Author(s):  
Yue Zhang ◽  
Xinyi Wan ◽  
Jianbo Gan ◽  
Cunde Wang
Keyword(s):  
Efficient Synthesis ◽  
Efficient Approach ◽  
Imidazole Derivatives

An efficient approach to the synthesis of 1,2,5-trisubstituted imidazole derivatives was investigated via DABCO-promoted formal [3 + 2] annulation reaction of substituted N-arylbenzimidamide and substituted β-nitrostyrenes. The annulation reaction is implemented easily to afford the corresponding products in moderate to good yields with excellent regioselectivity.

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