Novel phthalocyanine-based polymeric micelles with high near-infrared photothermal conversion efficiency under 808 nm laser irradiation for in vivo cancer therapy

2019 ◽  
Vol 7 (14) ◽  
pp. 2247-2251 ◽  
Author(s):  
Lu Li ◽  
Qingzhu Yang ◽  
Lei Shi ◽  
Nannan Zheng ◽  
Zeyu Li ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cancer Cells ◽  
Laser Irradiation ◽  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Polymeric Micelles ◽  
Photothermal Conversion ◽  
Phthalocyanine Molecule

Novel phthalocyanine molecule 4OCSPC with deep NIR absorbance showed excellent photothermal therapy property for cancer cells.

Metallic oxide nanocrystals with near-infrared plasmon resonance for efficient, stable and biocompatible photothermal cancer therapy

2017 ◽  
Vol 5 (35) ◽  
pp. 7393-7402 ◽  
Author(s):  
Kang Dou ◽  
Wenwen Zhu ◽  
Yousheng Zou ◽  
Yu Gu ◽  
Jubin Li ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cancer Cells ◽  
Laser Irradiation ◽  
Plasmon Resonance ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Temperature Elevation ◽  
Inhibition Rate ◽  
Metallic Oxide ◽  
Tumor Inhibition

The synthesized MoO2 nanocrystals exhibit excellent photothermal temperature elevation of about 37.5 °C under 808 nm laser irradiation, and tumor inhibition effects with an inhibition rate of up to 80.45% as a photothermal therapy agent against 4T1 cancer cells.

scholarly journals Boosting Chemodynamic Therapy by the Synergistic Effect of Co-Catalyze and Photothermal Effect Triggered by the Second Near-Infrared Light

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Songtao Zhang ◽  
Longhai Jin ◽  
Jianhua Liu ◽  
Yang Liu ◽  
Tianqi Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Bovine Serum Albumin ◽  
Synergistic Effect ◽  
Bovine Serum ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Photothermal Effect ◽  
Reaction Efficiency

AbstractIn spite of the tumor microenvironments responsive cancer therapy based on Fenton reaction (i.e., chemodynamic therapy, CDT) has been attracted more attentions in recent years, the limited Fenton reaction efficiency is the important obstacle to further application in clinic. Herein, we synthesized novel FeO/MoS2 nanocomposites modified by bovine serum albumin (FeO/MoS2-BSA) with boosted Fenton reaction efficiency by the synergistic effect of co-catalyze and photothermal effect of MoS2 nanosheets triggered by the second near-infrared (NIR II) light. In the tumor microenvironments, the MoS2 nanosheets not only can accelerate the conversion of Fe3+ ions to Fe2+ ions by Mo4+ ions on their surface to improve Fenton reaction efficiency, but also endow FeO/MoS2-BSA with good photothermal performances for photothermal-enhanced CDT and photothermal therapy (PTT). Consequently, benefiting from the synergetic-enhanced CDT/PTT, the tumors are eradicated completely in vivo. This work provides innovative synergistic strategy for constructing nanocomposites for highly efficient CDT.

scholarly journals A narrow-bandgap benzobisthiadiazole derivative with high near-infrared photothermal conversion efficiency and robust photostability for cancer therapy

2015 ◽  
Vol 51 (20) ◽  
pp. 4223-4226 ◽  
Author(s):  
Shuo Huang ◽  
Ravi Kumar Kannadorai ◽  
Yuan Chen ◽  
Quan Liu ◽  
Mingfeng Wang
Keyword(s):  
Cancer Therapy ◽  
Cancer Cells ◽  
Conversion Efficiency ◽  
Near Infrared ◽  
Therapeutic Agent ◽  
Infrared Region ◽  
Strong Absorption ◽  
Agent Based ◽  
Narrow Bandgap ◽  
Near Infrared Region

A novel photothermal therapeutic agent based on a narrow-bandgap benzobisthiadiazole derivative shows strong absorption in the near-infrared region, high photothermal efficiency and robust photostability for treatment of cancer cells.

Shape tunable gallium nanorods mediated tumor enhanced ablation through near-infrared photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 2655-2667 ◽  
Author(s):  
Xuyang Sun ◽  
Mengmeng Sun ◽  
Miaomiao Liu ◽  
Bo Yuan ◽  
Weiping Gao ◽  
...  
Keyword(s):  
Liquid Metal ◽  
Metal Nanoparticles ◽  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Photothermal Conversion

Shape tunable liquid metal nanoparticles were fabricated with characterization of biocompatibility, favorable photothermal conversion efficiency and tumor targeting capability for photothermal therapy.

Multifunctional Cu–Ag2S nanoparticles with high photothermal conversion efficiency for photoacoustic imaging-guided photothermal therapy in vivo

Nanoscale ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 825-831 ◽  
Author(s):  
Lile Dong ◽  
Guanming Ji ◽  
Yu Liu ◽  
Xia Xu ◽  
Pengpeng Lei ◽  
...  
Keyword(s):  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
The Novel ◽  
Photothermal Conversion ◽  
Ag2s Nanoparticles

The novel Cu–Ag2S/PVP NPs with high photothermal conversion efficiency could be employed as effective photoacoustic imaging guided photothermal therapy agents.

PEGylated nickel carbide nanocrystals as efficient near-infrared laser induced photothermal therapy for treatment of cancer cells in vivo

Nanoscale ◽  
2014 ◽  
Vol 6 (21) ◽  
pp. 12591-12600 ◽  
Author(s):  
Zhiguo Zhou ◽  
Jun Wang ◽  
Wei Liu ◽  
Chao Yu ◽  
Bin Kong ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Laser ◽  
Nickel Carbide

scholarly journals Near-Infrared Fluorescent Sorbitol Probe for Targeted Photothermal Cancer Therapy

Cancers ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1286 ◽  
Author(s):  
Lee ◽  
Jung ◽  
Jo ◽  
Yang ◽  
Koh ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Laser Irradiation ◽  
Near Infrared ◽  
Photothermal Effect ◽  
Great Promise ◽  
Targeted Cancer Therapy ◽  
Potential Applications ◽  
Photothermal Property ◽  
Nir Laser

Abstract: Photothermal therapy (PTT) using a near-infrared (NIR) heptamethine cyanine fluorophore has emerged as an alternative strategy for targeted cancer therapy. NIR fluorophores showing a high molar extinction coefficient and low fluorescence quantum yield have considerable potential applications in photothermal cancer therapy. In this study, a bifunctional sorbitol–ZW800 conjugate was used as an advanced concept of photothermal therapeutic agents for in vivo cancer imaging and therapy owing to the high tumor targetability of the sorbitol moiety and excellent photothermal property of NIR heptamethine cyanine fluorophore. The sorbitol–ZW800 showed an excellent photothermal effect increased by 58.7 °C after NIR laser irradiation (1.1 W/cm2) for 5 min. The HT-29 tumors targeted by sorbitol–ZW800 showed a significant decrease in tumor volumes for 7 days after photothermal treatment. Therefore, combining the bifunctional sorbitol–ZW800 conjugate and NIR laser irradiation is an alternative way for targeted cancer therapy, and this approach holds great promise as a safe and highly efficient NIR photothermal agent for future clinical applications.

Cu7.2S4 nanocrystals: a novel photothermal agent with a 56.7% photothermal conversion efficiency for photothermal therapy of cancer cells

Nanoscale ◽  
2014 ◽  
Vol 6 (6) ◽  
pp. 3274 ◽  
Author(s):  
Bo Li ◽  
Qian Wang ◽  
Rujia Zou ◽  
Xijian Liu ◽  
Kaibing Xu ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Photothermal Conversion
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