Bacteria encapsulation and rapid antibiotic susceptibility test using a microfluidic microwell device integrating surface-enhanced Raman scattering

Lab on a Chip ◽  
2020 ◽  
Vol 20 (14) ◽  
pp. 2520-2528 ◽  
Author(s):  
Hsiu-Kang Huang ◽  
Ho-Wen Cheng ◽  
Cheng-Chieh Liao ◽  
Shang-Jyun Lin ◽  
Yi-Zih Chen ◽  
...  
Keyword(s):  
Raman Scattering ◽  
High Throughput ◽  
Antibiotic Susceptibility ◽  
Susceptibility Test ◽  
Sers Substrate ◽  
Antibiotic Susceptibility Test ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

We developed a microfluidic microwell device integrating SERS substrate for an efficient bacteria encapsulation and enrichment followed by in situ SERS-AST measurement, which can potentially apply for high throughput and multi-parallel AST.

scholarly journals Facile In Situ Photochemical Synthesis of Silver Nanoaggregates for Surface-Enhanced Raman Scattering Applications

Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 685 ◽  
Author(s):  
Zhen Yin ◽  
Huilin He ◽  
Zhenming Wang ◽  
Xiaoguo Fang ◽  
Chunxiang Xu ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Microfluidic Channel ◽  
Surface Enhanced Raman Scattering ◽  
Photochemical Synthesis ◽  
Sers Substrate ◽  
Relative Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Recently, photochemical synthesis has attracted wide interest on in situ preparing the surface-enhanced Raman scattering (SERS) substrate with excellent performance, especially in a compact space and microfluidic channel. Herein, a facile, green and cost-effective approach to in situ photochemically synthesize silver nanoaggregates is demonstrated for SERS applications. By adjusting the photo-irradiation conditions, the morphologies and sizes of the silver nanoaggregates can be deliberately tailored. The synthesized silver nanoaggregates-based substrates exhibit a highly sensitive and reproducible SERS activity with a low detection limit of 10−8 M for 4-Aminothiophenol detection and relative standard deviation of 12.3%, paving an efficient and promising route for in situ SERS-based rapid detection in the environmental monitoring and food quality control.

scholarly journals Flexible SERS substrate of silver nanoparticles on cotton swabs for rapid in-situ detection of melamine

2022 ◽  
Author(s):  
Wen-Chien Huang ◽  
Ken-Fa Cheng ◽  
Jing-Yuan Shyu
Keyword(s):  
Silver Nanoparticles ◽  
Food Safety ◽  
Raman Scattering ◽  
Sers Substrate ◽  
Fast Method ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
In Situ Detection

It is important to be able to detect melamine via a sensitive and fast method in the field of food safety. Surface-enhanced Raman scattering (SERS) has attracted much attention due...

In-Situ Detection of Fluid Media Based on Three-Dimensional Dendritic Silver Surface-Enhanced Raman Scattering Substrate

2022 ◽  
Author(s):  
Sha Li ◽  
Zezhou Wang ◽  
Yunpeng Shao ◽  
Kai Zhang ◽  
Linyu Mei ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Three Dimensional ◽  
Microfluidic Channel ◽  
Surface Enhanced Raman Scattering ◽  
Sers Substrate ◽  
Silver Surface ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

In this paper, a highly active surface enhanced Raman scattering (SERS) substrate based on three-dimensional (3D) dendritic silver nanostructure was constructed in microfluidic channel by one-step electrodisplacement reaction for in-situ...

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