scholarly journals Synthesis and biological evaluation of a monocyclic Fc-binding antibody-recruiting molecule for cancer immunotherapy

2021 ◽  
Author(s):  
Koichi Sasaki ◽  
Kyohei Muguruma ◽  
Rento Osawa ◽  
Akane Fukuda ◽  
Atsuhiko Taniguchi ◽  
...  
Keyword(s):  
Immune Response ◽  
Cancer Cells ◽  
Nk Cell ◽  
Folate Receptor ◽  
Biological Evaluation ◽  
Binding Peptide ◽  
Simple Preparation ◽  
Cell Mediated Immune Response ◽  
Binding Antibody ◽  
Synthesis And Biological Evaluation

A monocyclic Fc-binding peptide “15-Lys8Leu” enables simple preparation of a Fc-binding antibody-recruiting molecule (Fc-ARM), which induces potent cytotoxicity against folate receptor positive cancer cells via NK cell-mediated immune response.

scholarly journals Synthesis and biological evaluation of nimesulide based new class of triazole derivatives as potential PDE4B inhibitors against cancer cells

2013 ◽  
Vol 23 (24) ◽  
pp. 6721-6727 ◽  
Author(s):  
Jyoti Mareddy ◽  
Suresh Babu Nallapati ◽  
Jayasree Anireddy ◽  
Yumnam Priyadarshini Devi ◽  
Lakshmi Narasu Mangamoori ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Biological Evaluation ◽  
Triazole Derivatives ◽  
New Class ◽  
Synthesis And Biological Evaluation

ChemInform Abstract: Synthesis and Biological Evaluation of KRIBB3 Analogues on a Proliferation of HCT-116 Colorectal Cancer Cells.

ChemInform ◽  
2011 ◽  
Vol 42 (17) ◽  
pp. no-no
Author(s):  
Sangku Lee ◽  
Jae Nyoung Kim ◽  
Ji Hye Min ◽  
Kab Seog Yoon ◽  
Ki Deok Shin ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Cells ◽  
Biological Evaluation ◽  
Colorectal Cancer Cells ◽  
Hct 116 ◽  
Synthesis And Biological Evaluation

scholarly journals Design, synthesis and biological evaluation of a new bridged immunosuppressor.

2001 ◽  
Vol 48 (4) ◽  
pp. 1147-1150 ◽  
Author(s):  
Z Szewczuk ◽  
A Wilczyński ◽  
I Petry ◽  
I Z Siemion ◽  
Z Wieczorek
Keyword(s):  
Immune Response ◽  
Humoral Immune Response ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Discontinuous Epitope ◽  
Humoral Immune ◽  
Hla Dq ◽  
Synthesis And Biological Evaluation

A bridged peptide with the sequence: H-Thr-Pro-Gln-Arg-Gly-Asp-Val-gamma-Abu-Asn-Asp-Gln-Glu-Glu-Thr-Thr-Gly-Val-Val-Ser-Thr-Pro-Leu-Ile-Arg-Asn-Gly-OH was designed to mimic the discontinuous epitope of the HLA-DQ molecule that might interact with CD4. The bridged peptide revealed distinct suppressory effect in the humoral immune response. This result supports our suggestion that the 164-172 region of the HLA-DQ molecule may enhance its interactions with coreceptors, possibly with CD4.

ChemInform Abstract: Synthesis and Biological Evaluation of Nimesulide Based New Class of Triazole Derivatives as Potential PDE4B Inhibitors Against Cancer Cells.

ChemInform ◽  
2014 ◽  
Vol 45 (20) ◽  
pp. no-no
Author(s):  
Jyoti Mareddy ◽  
Suresh Babu Nallapati ◽  
Jayasree Anireddy ◽  
Yumnam Priyadarshini Devi ◽  
Lakshmi Narasu Mangamoori ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Biological Evaluation ◽  
Triazole Derivatives ◽  
New Class ◽  
Synthesis And Biological Evaluation

scholarly journals 99mTc-tetraethylenepentamine-folate a new 99mTc based folate derivative for the detection of folate receptor positive tumors: Synthesis and biological evaluation

2004 ◽  
Vol 3 (10) ◽  
pp. 995-1001 ◽  
Author(s):  
Puja Panwar ◽  
Vibha Shrivastava ◽  
Vibha Tandon ◽  
Pushpa Mishra ◽  
Krishna Chuttani ◽  
...  
Keyword(s):  
Folate Receptor ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation
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