Digital counting of single semiconducting polymer nanoparticles for the detection of alkaline phosphatase

Nanoscale ◽  
2021 ◽  
Author(s):  
Shumin Wang ◽  
Mengna Huang ◽  
Jianhao Hua ◽  
Lin Wei ◽  
Shen Lin ◽  
...  

The single particle enumeration (SPE) method is proposed for the detection of alkaline phosphatase (ALP) based on the fluorescence suppression by polydopamine shell on the surface of semiconducting polymer nanoparticles (SPNs).

2021 ◽  
Vol 57 (16) ◽  
pp. 1989-2004
Author(s):  
Junyong Sun ◽  
Qiang Zhang ◽  
Xiaomei Dai ◽  
Pinghua Ling ◽  
Feng Gao

We summarize the recent advances in engineering approaches to obtain functionalized semiconducting polymer nanoparticles (SPNs) for biological applications. The challenges and outlook of fabricating functionalized SPNs are also provided.


2018 ◽  
Vol 9 (12) ◽  
pp. 3105-3110 ◽  
Author(s):  
Kangquan Shou ◽  
Yufu Tang ◽  
Hao Chen ◽  
Si Chen ◽  
Lei Zhang ◽  
...  

PDFT1032, a new semiconducting polymer possessing a favorable absorption peak (1032 nm) and outstanding biocompatibility, may be widely applicable in clinical imaging and the surgical treatment of malignancy.


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