scholarly journals An ε-caprolactone-derived 2-oxazoline inimer for the synthesis of graft copolymers

2020 ◽  
Vol 11 (42) ◽  
pp. 6847-6852
Author(s):  
Jungyeon Kim ◽  
Christopher Waldron ◽  
Beatrice Cattoz ◽  
C. Remzi Becer
Keyword(s):  
Ring Opening ◽  
Graft Copolymers ◽  
Starting Material

An inimer-like structure that consists of a 2-oxazoline ring for cationic ring opening polymerisation and a typical alpha-bromo ester initiator for Cu-RDRP has been synthesised using ε-Caprolactone as the starting material.

Construction the A-B bicyclic ring structure of Stemocurtisisne

2020 ◽  
Vol 17 ◽  
Author(s):  
Duc Dau Xuan
Keyword(s):  
Glutamic Acid ◽  
Natural Product ◽  
Mannich Reaction ◽  
Boronic Acid ◽  
Ring Opening ◽  
Ring Structure ◽  
Starting Material ◽  
Epoxide Ring ◽  
Epoxide Ring Opening

: The synthesis of the A-B bicyclic ring structure 3 of the natural product Stemocurtisine is described. The synthesis was accomplished in seven synthetic steps from commercially available L-glutamic acid. The key step involved a borono-Mannich reaction between the hemiaminal 6 and trans-β-styryl boronic acid and trans-β-styrylpotassiumtrifluoroborate to prepare the cis diene 4. Attempts to prepare the A-B-C ring compound 2 via intramolecular epoxide ring opening followed by rearangement under different basic conditions were unsuccessful. Only unreactive starting material was recovered.

Block and graft copolymers based on cationic ring-opening polymerizations

1992 ◽  
Vol 64 (1) ◽  
pp. 113-120 ◽  
Author(s):  
Eric J. Goethals ◽  
Veska Toncheva ◽  
Fried'l Hosteaux ◽  
Saskia Walraedt ◽  
Ronny de Clercq
Keyword(s):  
Ring Opening ◽  
Graft Copolymers

Synthesis of biodegradable protein–poly(ε-caprolactone) conjugates via enzymatic ring opening polymerization

2020 ◽  
Vol 11 (3) ◽  
pp. 682-686 ◽  
Author(s):  
Chunyang Bao ◽  
Xiaoling Xu ◽  
Jing Chen ◽  
Qiang Zhang
Keyword(s):  
Ring Opening ◽  
Graft Copolymers ◽  
Ring Opening Polymerization ◽  
Amphiphilic Graft Copolymers

Lipase–poly(HEAA) conjugates act as initiators and catalysts simultaneously for the eROP of ε-CL, forming biodegradable conjugates with amphiphilic graft copolymers.

Synthesis and ring-opening polymerisation of a new alkyne-functionalised glycolide towards biocompatible amphiphilic graft copolymers

2013 ◽  
Vol 4 (13) ◽  
pp. 3705 ◽  
Author(s):  
Fanny Coumes ◽  
Vincent Darcos ◽  
Dominique Domurado ◽  
Suming Li ◽  
Jean Coudane
Keyword(s):  
Ring Opening ◽  
Graft Copolymers ◽  
Amphiphilic Graft Copolymers

scholarly journals From Bioactive Pyrrolidino[3,4-c]pyrrolidines to more Bioactive Pyrrolidino[3,4-b]pyrrolidines via Ring-Opening/Ring-Closing Promoted by Sodium Methoxide

Synthesis ◽  
2018 ◽  
Vol 51 (07) ◽  
pp. 1565-1577 ◽  
Author(s):  
H. Dondas ◽  
José Sansano ◽  
Samet Belveren ◽  
Olatz Larrañaga ◽  
Samet Poyraz ◽  
...  
Keyword(s):  
Ring Opening ◽  
Sodium Methoxide ◽  
Starting Material ◽  
Computational Studies ◽  
Quaternary Carbons

The process involving a rearrangement of pyrrolidino[3,4-c]pyrrolidine to another pyrrolidino[3,4-b]pyrrolidine using sodium methoxide as base is fully studied. The effects of the substituents are analyzed during the ring-opening/ring-closing sequence. Computational studies are also performed to explain the importance of susbstituents and quaternary carbons, especially when the (3-indolyl)methyl is present in the starting material. Finally, all the samples are evaluated as potential candidates for antibacterial and antimycobacterial activities.

Asymmetric Synthesis of cis-5-(Aminomethyl)-3-(4-methoxy­phenyl)dihydrofuran-2(3H)-one

Synthesis ◽  
2018 ◽  
Vol 51 (04) ◽  
pp. 885-888 ◽  
Author(s):  
Won Lee ◽  
Hyun-Joon Ha ◽  
Sonhwan Kim
Keyword(s):  
Asymmetric Synthesis ◽  
Ring Opening ◽  
Starting Material ◽  
Synthetic Method ◽  
Aziridine Ring

The asymmetric synthesis of (3R,5S)-5-(aminomethyl)-3-(4-methoxyphenyl)dihydrofuran-2(3H)-one, as the most potent selective inactivator of monoamine B, was successfully achieved by applying a newly developed synthetic method toward the key γ-aminomethyl-γ-lactone via intramolecular aziridine ring opening in 63% overall yield from a commercial starting material.

Thermosensitive Micelles Composed of Poly(lactide)-g-Poly(NIPAM-co-HEMA) Graft Copolymers

2010 ◽  
Vol 459 ◽  
pp. 51-56 ◽  
Author(s):  
Tran Minh Quynh ◽  
Masaru Yoneyama ◽  
Yasuyuki Maki ◽  
Naotsugu Nagasawa ◽  
Toshiaki Dobashi
Keyword(s):  
Ring Opening ◽  
Graft Copolymers ◽  
Optical Transmittance ◽  
Ring Opening Polymerization ◽  
Hydroxyethyl Methacrylate ◽  
Force Microscopy ◽  
Atomic Force ◽  
Methacrylate Copolymers ◽  
Spherical Structures ◽  
Cloud Point Temperature

Different poly(N-isopropylacrylamide-co-hydroxyethyl methacrylate) copolymers (P(NIPAM-co-HEMA)) were synthesized from N-isopropylacrylamide (NIPA) and hydroxyethyl methacrylate (HEMA) comonomers by both radical and radiation polymerizations for comparison. PLLA-g-P(NIPAM-co-HEMA) graft copolymers were synthesized from L-lactide and respective P(NIPAM-co-HEMA) copolymers by ring opening polymerization. Both NMR and FTIR analyses demonstrated the PLLA chains have been grafted on to the P(NIPAM-co-HEMA) backbone. These graft copolymers revealed the cloud point temperature higher than that of PNIPAM homopolymer as determined by optical transmittance. The graft copolymers self-assembled into micelles with regularly spherical structures as observed by atomic force microscopy (AFM). The properties of these graft copolymers are interesting for the drug delivery system.

Sign in / Sign up

Export Citation Format

Share Document