Metal-free synthesis of 3-chalcogenyl chromones from alkynyl aryl ketones and diorganyl diselenides/disulfides mediated by PIFA

2020 ◽  
Vol 7 (23) ◽  
pp. 3935-3940
Author(s):  
Zhenkang Ai ◽  
Jiaxi Xiao ◽  
Yadong Li ◽  
Boying Guo ◽  
Yunfei Du ◽  
...  
Keyword(s):  
Metal Free ◽  
Aryl Ketones

3-Selenyl/sulfenyl chromones/thiochromones were conveniently synthesized from the PIFA-mediated reactions between alkynyl aryl ketones bearing an ortho-methoxy/methylthio group and diorganyl diselenides/disulfides.

Metal-Free Photoinduced Transformation of Aryl Halides and Diketones into Aryl Ketones

2019 ◽  
Vol 2019 (16) ◽  
pp. 2721-2724 ◽  
Author(s):  
Qiuli Yao ◽  
Wenbo Liu ◽  
Peng Liu ◽  
Linjing Ren ◽  
Xuehong Fang ◽  
...  
Keyword(s):  
Aryl Halides ◽  
Metal Free ◽  
Aryl Ketones ◽  
Photoinduced Transformation

Metal-Free Synthesis of 2,4,6-Trisubstituted Pyridines via Iodine-Initiated Reaction of Methyl Aryl Ketones with Amines under Neat Heating

Synthesis ◽  
2016 ◽  
Vol 49 (08) ◽  
pp. 1879-1883 ◽  
Author(s):  
Ze Zhang ◽  
Hui Xu ◽  
Ji-Chao Zeng ◽  
Fang-Jian Wang
Keyword(s):  
Metal Free ◽  
Aryl Ketones

ChemInform Abstract: Transition-Metal-Free α-Arylation of Enolizable Aryl Ketones and Mechanistic Evidence for a Radical Process.

ChemInform ◽  
2016 ◽  
Vol 47 (4) ◽  
pp. no-no
Author(s):  
Martin Pichette Drapeau ◽  
Indira Fabre ◽  
Laurence Grimaud ◽  
Ilaria Ciofini ◽  
Thierry Ollevier ◽  
...  
Keyword(s):  
Transition Metal ◽  
Radical Process ◽  
Metal Free ◽  
Aryl Ketones

Iodine- and TBHP-Promoted Acylation of Benzothiazoles under Metal-Free Conditions

Synthesis ◽  
2020 ◽  
Author(s):  
Keyume Ablajan ◽  
Bin Wang ◽  
Qianwei Zhang ◽  
Zhongqi Guo
Keyword(s):  
Ring Opening ◽  
Amino Group ◽  
Metal Free ◽  
Product Yields ◽  
Broad Scope ◽  
Simple Protocol ◽  
Aryl Ketones ◽  
Aryl Ketone

A simple protocol for the synthesis of 2-acylbenzothiazoles using aryl ketones and benzothiazoles in the presence of I2 and TBHP is described. Acylation of the benzothiazoles is achieved through a sequence involving oxidation of the aryl ketone to an aryl glyoxal, ring-opening of the benzothiazole followed by condensation of the amino group with the aryl glyoxal, cyclization and oxidation. The method avoids the use of metals and toxic solvents. In addition, this protocol has the advantage of broad scope and provides good to excellent product yields.

scholarly journals α-Acetoxyarone synthesis via iodine-catalyzed and tert-butyl hydroperoxide-mediateded self-intermolecular oxidative coupling of aryl ketones

2017 ◽  
Vol 13 ◽  
pp. 1079-1084 ◽  
Author(s):  
Liquan Tan ◽  
Cui Chen ◽  
Weibing Liu
Keyword(s):  
Oxidative Coupling ◽  
Optimum Conditions ◽  
Butyl Hydroperoxide ◽  
Metal Free ◽  
Tert Butyl ◽  
Radical Intermediates ◽  
Tert Butyl Hydroperoxide ◽  
Aryl Ketones

We present a metal-free method for α-acetoxyarone synthesis by self-intermolecular oxidative coupling of aryl ketones using I2−tert-butyl hydroperoxide (TBHP). Under the optimum conditions, various aryl ketones gave the corresponding products in moderate to excellent yields. A series of control experiments were performed; the results suggest the involvement of radical pathways. Multiple radical intermediates were generated in situ and the overall process involved several different reactions, which proceeded self-sequentially in a single reactor. A labeling experiment using 18O-labeled H2O confirmed that the oxygen in the product was derived from TBHP, not from H2O in the TBHP solvent.

ChemInform Abstract: One-Step Metal-Free Construction of Fluorescent 5-Aryl-2,3-dicyanofurans from Simple Aryl Ketones with DDQ.

ChemInform ◽  
2014 ◽  
Vol 45 (29) ◽  
pp. no-no
Author(s):  
Jiang-Sheng Li ◽  
Fei-Fei Cai ◽  
Zhi-Wei Li ◽  
Wei-Dong Liu ◽  
Jim Simpson ◽  
...  
Keyword(s):  
Metal Free ◽  
Free Construction ◽  
Aryl Ketones ◽  
One Step

Construction of benzofuranone library via a metal-free, one-pot intermolecular condensation, and their application as efficient estrogen receptor β modulators

2019 ◽  
Vol 55 (97) ◽  
pp. 14570-14573 ◽  
Author(s):  
Xueke Peng ◽  
Zhiye Hu ◽  
Jing Zhang ◽  
Wentao Ning ◽  
Silong Zhang ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Β ◽  
Facile Synthesis ◽  
One Pot ◽  
Metal Free ◽  
Aryl Ketones

Facile synthesis of benzofuranones as efficient estrogen receptor β modulators was achieved through a metal-free, one-pot intermolecular condensation between α-hydroxy aryl ketones and resorcinol derivatives.

Transition metal-free synthesis of α-aryl ketones via oxyallyl cation capture with arylboronic acids

2020 ◽  
Vol 7 (17) ◽  
pp. 2480-2485 ◽  
Author(s):  
Wei-Hua Huang ◽  
Gong-Bin Huang ◽  
Wen-Run Zhu ◽  
Jiang Weng ◽  
Gui Lu
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
Arylboronic Acids ◽  
Aryl Ketones ◽  
Substrate Tolerance ◽  
Oxyallyl Cation

α-Arylated ketones were accessed via oxyallyl cation capture with arylboronic acids in good yields with broad substrate tolerance.

Easy access to secondary and tertiary alcohols via metal-free and light mediated radical carbonyl allylation

2021 ◽  
Vol 57 (82) ◽  
pp. 10783-10786
Author(s):  
Benjamin Rui Peng Yip ◽  
Kumar Bhaskar Pal ◽  
Junjie Desmond Lin ◽  
Yuan Xu ◽  
Mrinmoy Das ◽  
...  
Keyword(s):  
Easy Access ◽  
Metal Free ◽  
Tertiary Alcohols ◽  
Aryl Ketones ◽  
Carbonyl Allylation

An organo-photocatalyst catalyzed allylation of aryl ketones and aldehydes using readily available unactivated allylic substrates has been reported.

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