Immune remodeling triggered by photothermal therapy with semiconducting polymer nanoparticles in combination with chemotherapy to inhibit metastatic cancers

2021 ◽  
Author(s):  
Yuming Yang ◽  
Minjie Xu ◽  
zhe Wang ◽  
Yanqing Yang ◽  
Jie Liu ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Photothermal Therapy ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Promising Strategy ◽  
Semiconducting Polymer Nanoparticles

Photothermal therapy (PTT) based on semiconducting Polymer Nanoparticles (SPNs) is a promising strategy to treat solid tumors, but their ability to combine with chemotherapy for immune remodeling to efficiently suppress...

Mussel-inspired functionalization of semiconducting polymer nanoparticles for amplified photoacoustic imaging and photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (31) ◽  
pp. 14727-14733 ◽  
Author(s):  
Biqing Bao ◽  
Li Tong ◽  
Yu Xu ◽  
Jingjing Zhang ◽  
Xue Zhai ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Semiconducting Polymer Nanoparticles

Semiconducting polymer nanoparticles encapsulated with polydopamine as both the protection and bioconjugation layer for amplified photoacoustic imaging and photothermal therapy are proposed.

Semiconducting Polymer Nanoparticles for NIR-II Fluorescence Imaging-guided Photothermal/Thermodynamic Combination Therapy

2022 ◽  
Author(s):  
Wenqi Wang ◽  
Xi Zhang ◽  
Xiaoyue Ni ◽  
Wen Zhou ◽  
Chen Xie ◽  
...  
Keyword(s):  
Heat Shock ◽  
Cancer Therapy ◽  
Combination Therapy ◽  
Heat Shock Protein ◽  
Fluorescence Imaging ◽  
Therapeutic Efficacy ◽  
Photothermal Therapy ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Semiconducting Polymer Nanoparticles

Photothermal therapy is a promising phototherapeutic modality which has been widely studied in the cancer therapy. However, because of the influence of heat shock protein (HSP), the therapeutic efficacy of...

1300 nm absorption two-acceptor semiconducting polymer nanoparticles for NIR-II photoacoustic imaging system guided NIR-II photothermal therapy

2019 ◽  
Vol 55 (64) ◽  
pp. 9487-9490 ◽  
Author(s):  
Wansu Zhang ◽  
Xiaoli Sun ◽  
Ting Huang ◽  
Xiaoxia Pan ◽  
Pengfei Sun ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Semiconducting Polymer Nanoparticles

1300 nm absorption SPNs were designed to realize in vivo NIR-II PTT treatment guided by commercial NIR-II PAI systems.

Engineering fluorescent semiconducting polymer nanoparticles for biological applications and beyond

2021 ◽  
Vol 57 (16) ◽  
pp. 1989-2004
Author(s):  
Junyong Sun ◽  
Qiang Zhang ◽  
Xiaomei Dai ◽  
Pinghua Ling ◽  
Feng Gao
Keyword(s):  
Polymer Nanoparticles ◽  
Biological Applications ◽  
Semiconducting Polymer ◽  
Recent Advances ◽  
Semiconducting Polymer Nanoparticles

We summarize the recent advances in engineering approaches to obtain functionalized semiconducting polymer nanoparticles (SPNs) for biological applications. The challenges and outlook of fabricating functionalized SPNs are also provided.

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