Semiconducting Polymer Nanoparticles for NIR-II Fluorescence Imaging-guided Photothermal/Thermodynamic Combination Therapy

2022 ◽  
Author(s):  
Wenqi Wang ◽  
Xi Zhang ◽  
Xiaoyue Ni ◽  
Wen Zhou ◽  
Chen Xie ◽  
...  
Keyword(s):  
Heat Shock ◽  
Cancer Therapy ◽  
Combination Therapy ◽  
Heat Shock Protein ◽  
Fluorescence Imaging ◽  
Therapeutic Efficacy ◽  
Photothermal Therapy ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Semiconducting Polymer Nanoparticles

Photothermal therapy is a promising phototherapeutic modality which has been widely studied in the cancer therapy. However, because of the influence of heat shock protein (HSP), the therapeutic efficacy of...

Cubic POSS engineering of photosensitizer-doped semiconducting polymer nanoparticles for enhanced fluorescence imaging and amplified photodynamic therapy

2020 ◽  
Vol 11 (44) ◽  
pp. 7035-7041
Author(s):  
Biqing Bao ◽  
Xue Zhai ◽  
Tianqi Liu ◽  
Peng Su ◽  
Luyao Zhou ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Fluorescence Imaging ◽  
Polymer Nanoparticles ◽  
Enhanced Fluorescence ◽  
Semiconducting Polymer ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Semiconducting Polymer Nanoparticles

PorPOSSC12 -doped semiconducting polymer nanoparticles with simultaneously enhanced fluorescence brightness and amplified singlet oxygen generation ability were designed for imaging-guided photodynamic therapy.

Mussel-inspired functionalization of semiconducting polymer nanoparticles for amplified photoacoustic imaging and photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (31) ◽  
pp. 14727-14733 ◽  
Author(s):  
Biqing Bao ◽  
Li Tong ◽  
Yu Xu ◽  
Jingjing Zhang ◽  
Xue Zhai ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Semiconducting Polymer Nanoparticles

Semiconducting polymer nanoparticles encapsulated with polydopamine as both the protection and bioconjugation layer for amplified photoacoustic imaging and photothermal therapy are proposed.

Immune remodeling triggered by photothermal therapy with semiconducting polymer nanoparticles in combination with chemotherapy to inhibit metastatic cancers

2021 ◽  
Author(s):  
Yuming Yang ◽  
Minjie Xu ◽  
zhe Wang ◽  
Yanqing Yang ◽  
Jie Liu ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Photothermal Therapy ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Promising Strategy ◽  
Semiconducting Polymer Nanoparticles

Photothermal therapy (PTT) based on semiconducting Polymer Nanoparticles (SPNs) is a promising strategy to treat solid tumors, but their ability to combine with chemotherapy for immune remodeling to efficiently suppress...

scholarly journals Highly stable semiconducting polymer nanoparticles for multi-responsive chemo/photothermal combined cancer therapy

Theranostics ◽  
2020 ◽  
Vol 10 (13) ◽  
pp. 5966-5978 ◽  
Author(s):  
Yu Xu ◽  
Xue Zhai ◽  
Peng Su ◽  
Tianqi Liu ◽  
Luyao Zhou ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Polymer Nanoparticles ◽  
Semiconducting Polymer ◽  
Semiconducting Polymer Nanoparticles

scholarly journals Enhanced efficacy of photothermal therapy by combining a semiconducting polymer with an inhibitor of a heat shock protein

2019 ◽  
Vol 3 (1) ◽  
pp. 127-136 ◽  
Author(s):  
Tingting Sun ◽  
Xingxing Chen ◽  
Xin Wang ◽  
Shi Liu ◽  
Jun Liu ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Photothermal Therapy ◽  
Semiconducting Polymer ◽  
Therapy Efficacy

The photothermal therapy efficacy of a semiconducting polymer could be enhanced by integrating an inhibitor of a heat shock protein.

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