Green Sensitive Spectrofluorimetric determination of Remdesvir, an FDA approved SARS-COV-2 Candidate Antiviral; Application in Pharmaceutical Dosage Forms and Spiked Human Plasma

2021 ◽  
Author(s):  
Heba Elmansi ◽  
Adel Ehab Ibrahim ◽  
Ibraam Mikhail ◽  
Fathalla Belal
Keyword(s):  
Quality Control ◽  
Human Plasma ◽  
Dosage Forms ◽  
Analytical Performance ◽  
Pharmaceutical Dosage Forms ◽  
Spiked Human Plasma ◽  
Fluorescent Spectroscopy ◽  
Spectrofluorimetric Determination

Fluorescent Spectroscopy has gained lots of interests pending the last years. Its advantages cover both; the analytical performance, as well as ecological greenness. The quality control of pharmaceuticals requires sensitive,...

scholarly journals Facile complexation reactions for the selective spectrofluorimetric determination of albendazole in oral dosage forms and spiked human plasma

RSC Advances ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. 5373-5381 ◽  
Author(s):  
Ahmed A. Hamad ◽  
Ramadan Ali ◽  
Hassan Refat H. Ali ◽  
Dalia M. Nagy ◽  
Sayed M. Derayea
Keyword(s):  
Human Plasma ◽  
Dosage Forms ◽  
Oral Dosage ◽  
Native Fluorescence ◽  
Spiked Human Plasma ◽  
Erythrosine B ◽  
Spectrofluorimetric Determination ◽  
Complexation Reactions ◽  
Oral Dosage Forms

Complexation of albendazole with erythrosine B quench the native fluorescence of the dye while complexation of the drug with lanthanum (iii) ions enhance the fluorescence of the drug.

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