The design criteria and therapeutic strategy of functional scaffold for spinal cord injury repair

2021 ◽  
Author(s):  
Jian Cao ◽  
Jiahe Wu ◽  
Jiafu Mu ◽  
Shiqing Feng ◽  
Jian-Qing Gao
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Therapeutic Strategy ◽  
Design Criteria ◽  
Therapeutic Challenge ◽  
Injury Repair ◽  
Cell Therapeutics ◽  
Current Drug ◽  
Cord Injury ◽  
Significant Efficacy

Spinal cord injury (SCI) remains a therapeutic challenge in clinic. Current drug and cell therapeutics have obtained significant efficacy but are still in the early stages for complete neural and...

Nanopharmaceutical-based regenerative medicine: Promising therapeutic strategy for spinal cord injury

2021 ◽  
Author(s):  
Chen Zhao ◽  
Zheng Xing ◽  
Chunchen Zhang ◽  
Yubo Fan ◽  
Haifeng Liu
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Regenerative Medicine ◽  
Neurological Disorder ◽  
Therapeutic Strategy ◽  
Severe Injury ◽  
Cord Injury

Spinal cord injury (SCI) is a neurological disorder that can lead to loss of perceptive and athletic function due to the severe injury of nerve. Nowadays, evidences detailing the precise...

Pentapeptide IKVAV-engineered hydrogels for neural stem cell attachment

2021 ◽  
Author(s):  
Yixia Yin ◽  
Wenwu Wang ◽  
Qi Shao ◽  
Binbin Li ◽  
Dan Yu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Neural Stem Cell ◽  
Cell Attachment ◽  
Injury Repair ◽  
Cord Injury ◽  
Proliferation Ability

A IKVAV-functionalized hydrogel is developed. It not only enhances neural stem cell (NSC) attachment, growth, and differentiation, but also maintains the proliferation ability of the NSC spheroids in the hydrogel for spinal cord injury repair.

Multiple drug delivery hydrogel system for spinal cord injury repair strategies

2012 ◽  
Vol 159 (2) ◽  
pp. 271-280 ◽  
Author(s):  
Giuseppe Perale ◽  
Filippo Rossi ◽  
Marco Santoro ◽  
Marco Peviani ◽  
Simonetta Papa ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Multiple Drug ◽  
Injury Repair ◽  
Cord Injury ◽  
Multiple Drug Delivery ◽  
Hydrogel System
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