scholarly journals A minimal standardized human bone marrow microphysiological system to assess resident cell behavior during normal and pathological processes

2022 ◽  
Author(s):  
Thibault Voeltzel ◽  
Gaëlle Fossard ◽  
Michaël Degaud ◽  
Kevin Geistlich ◽  
Nicolas Gadot ◽  
...  

We provide an easy to access microphysiological standardized system approaching the human bone marrow complexity to a first level of analysis by in situ imaging or by viable cell harvesting of processes taking place within this ecosystem.

2007 ◽  
Vol 82A (1) ◽  
pp. 195-200 ◽  
Author(s):  
Kenji Maekawa ◽  
Yasuhiro Yoshida ◽  
Atsushi Mine ◽  
Takuo Fujisawa ◽  
Bart Van Meerbeek ◽  
...  

2008 ◽  
Vol 71 (3) ◽  
pp. 313-321 ◽  
Author(s):  
H.-P. Horny ◽  
U. Engst ◽  
R. S. Walz ◽  
E. Kaiserling

2015 ◽  
Vol 24 (6) ◽  
pp. 1067-1083 ◽  
Author(s):  
Min Sung Park ◽  
Yun Hee Kim ◽  
Youngmee Jung ◽  
Soo Hyun Kim ◽  
Jong Chul Park ◽  
...  

1988 ◽  
Vol 168 (3) ◽  
pp. 1193-1198 ◽  
Author(s):  
S H Lee ◽  
P R Crocker ◽  
S Westaby ◽  
N Key ◽  
D Y Mason ◽  
...  

Stromal macrophages (M phi) have been localized in situ and isolated within erythroid clusters from human marrow. Stromal M phi arborize in an extensive network uniformly distributed throughout marrow interstitium, and express the phenotype CD4+, CD11a+, CD11c+, CD13+, CD14+, CD16+, CD18+, CD31+, CD32+, FcRI+, HLA-DR+, and CD35-, transferrin receptor-negative, and CD11b (weak). They express endocytic receptor antigens, but show significant differences in myeloid antigen expression compared with freshly harvested or cultured monocytes. Human stromal M phi are therefore specialized mature marrow M phi that are accessible for further investigations in infectious, storage, or hemopoietic disorders.


1986 ◽  
Vol 62 (2) ◽  
pp. 287-292 ◽  
Author(s):  
Giovanni Emilia ◽  
Amedea Donelli ◽  
Sergio Ferrari ◽  
Umberto Torelli ◽  
Licia Selleri ◽  
...  

2017 ◽  
Author(s):  
D Pal ◽  
H Blair ◽  
S Boyd ◽  
P Bakelis ◽  
A Elder ◽  
...  

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