Cell morphology as a design parameter in the bioengineering of cell-biomaterial surface interactions.

2021 ◽  
Author(s):  
Oliver George Frost ◽  
Nazanin Owji ◽  
Richard Thorogate ◽  
Christos Kyriakidis ◽  
Prasad Sawadkar ◽  
...  
Keyword(s):  
Cell Culture ◽  
Cell Surface ◽  
Cell Morphology ◽  
Design Parameter ◽  
Surface Interactions ◽  
Surface Interaction ◽  
Emergent Property ◽  
Functional Coatings ◽  
Cell Sheets ◽  
Biomaterial Surface

Control of cell-surface interaction is necessary for biomaterial applications such as cell sheets, intelligent cell culture surfaces, or functional coatings. In this paper, we propose the emergent property of cell...

Amine-Rich Organic Thin Films for Cell Culture: Possible Electrostatic Effects in Cell–Surface Interactions

2012 ◽  
Vol 51 ◽  
pp. 11PJ04 ◽  
Author(s):  
Michael R. Wertheimer ◽  
Amélie St-Georges-Robillard ◽  
Sophie Lerouge ◽  
Fackson Mwale ◽  
Bentsian Elkin ◽  
...  
Keyword(s):  
Thin Films ◽  
Cell Culture ◽  
Cell Surface ◽  
Organic Thin Films ◽  
Surface Interactions ◽  
Electrostatic Effects ◽  
Cell Surface Interactions

Evaluation of cell-surface interaction using a 3D spheroid cell culture model on artificial extracellular matrices

2017 ◽  
Vol 73 ◽  
pp. 310-318 ◽  
Author(s):  
Wolfgang Metzger ◽  
Sandra Rother ◽  
Tim Pohlemann ◽  
Stephanie Möller ◽  
Matthias Schnabelrauch ◽  
...  
Keyword(s):  
Cell Culture ◽  
Cell Surface ◽  
Surface Interaction ◽  
Extracellular Matrices ◽  
Cell Culture Model ◽  
Culture Model ◽  
Spheroid Cell Culture

Amine-Rich Organic Thin Films for Cell Culture: Possible Electrostatic Effects in Cell–Surface Interactions

2012 ◽  
Vol 51 (11S) ◽  
pp. 11PJ04 ◽  
Author(s):  
Michael R. Wertheimer ◽  
Amélie St-Georges-Robillard ◽  
Sophie Lerouge ◽  
Fackson Mwale ◽  
Bentsian Elkin ◽  
...  
Keyword(s):  
Thin Films ◽  
Cell Culture ◽  
Cell Surface ◽  
Organic Thin Films ◽  
Surface Interactions ◽  
Electrostatic Effects ◽  
Cell Surface Interactions

scholarly journals Endogenous hyaluronate-cell surface interactions in 3T3 and simian virus-transformed 3T3 cells.

1984 ◽  
Vol 259 (15) ◽  
pp. 9440-9446
Author(s):  
R L Goldberg ◽  
J D Seidman ◽  
G Chi-Rosso ◽  
B P Toole
Keyword(s):  
Cell Surface ◽  
Surface Interactions ◽  
Simian Virus ◽  
3T3 Cells ◽  
Cell Surface Interactions

scholarly journals Self-organization and culture of Mesenchymal Stem Cell spheroids in acoustic levitation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nathan Jeger-Madiot ◽  
Lousineh Arakelian ◽  
Niclas Setterblad ◽  
Patrick Bruneval ◽  
Mauricio Hoyos ◽  
...  
Keyword(s):  
Cell Culture ◽  
3D Cell Culture ◽  
Culture Conditions ◽  
Acoustic Levitation ◽  
Cell Sheets ◽  
Cell Therapies ◽  
Cellular Models ◽  
Cell Spheroids

AbstractIn recent years, 3D cell culture models such as spheroid or organoid technologies have known important developments. Many studies have shown that 3D cultures exhibit better biomimetic properties compared to 2D cultures. These properties are important for in-vitro modeling systems, as well as for in-vivo cell therapies and tissue engineering approaches. A reliable use of 3D cellular models still requires standardized protocols with well-controlled and reproducible parameters. To address this challenge, a robust and scaffold-free approach is proposed, which relies on multi-trap acoustic levitation. This technology is successfully applied to Mesenchymal Stem Cells (MSCs) maintained in acoustic levitation over a 24-h period. During the culture, MSCs spontaneously self-organized from cell sheets to cell spheroids with a characteristic time of about 10 h. Each acoustofluidic chip could contain up to 30 spheroids in acoustic levitation and four chips could be ran in parallel, leading to the production of 120 spheroids per experiment. Various biological characterizations showed that the cells inside the spheroids were viable, maintained the expression of their cell surface markers and had a higher differentiation capacity compared to standard 2D culture conditions. These results open the path to long-time cell culture in acoustic levitation of cell sheets or spheroids for any type of cells.

Lymphoid Cell Surface Interaction Structures Detected Using Cytolysis-Inhibiting Monoclonal Antibodies

1982 ◽  
Vol 68 (1) ◽  
pp. 5-42 ◽  
Author(s):  
Pierre Golstein ◽  
Christo Goridis ◽  
Anne-Marie Schmitt-Verhulst ◽  
Brigitte Hayot ◽  
Anne Pierres ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Cell Surface ◽  
Lymphoid Cell ◽  
Surface Interaction
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