Interrogating Biomineralization One Amino Acid at a Time: Amplification of Mutational Effects in Protein-Aided Titania Morphogenesis through Reaction-Diffusion Control

2021 ◽  
Author(s):  
Karthik Pushpavanam ◽  
Brittney Hellner ◽  
François Baneyx
Keyword(s):  
Amino Acid ◽  
Reaction Diffusion ◽  
Diffusion Chamber ◽  
Diffusion Control ◽  
Inorganic Precursor ◽  
Agarose Hydrogel ◽  
Time Amplification

To emulate the control that biomineralizing organisms exert over reactant transport, we construct a countercurrent reaction-diffusion chamber in which an agarose hydrogel regulates the fluxes of inorganic precursor and precipitating...

scholarly journals Reaction-diffusion control in somitogenesis

2001 ◽  
Vol 41 (supplement) ◽  
pp. S186
Author(s):  
J. Ozaki ◽  
M. Hirata ◽  
S. Kondo
Keyword(s):  
Reaction Diffusion ◽  
Diffusion Control

Some Analytical Criteria for Local Activity of Three-Port CNN with Four State Variables: Analysis and Applications

2003 ◽  
Vol 13 (08) ◽  
pp. 2189-2239 ◽  
Author(s):  
Lequan Min ◽  
Jingtao Wang ◽  
Xisong Dong ◽  
Guanrong Chen
Keyword(s):  
Numerical Simulations ◽  
Wide Spectrum ◽  
Immune Surveillance ◽  
Reaction Diffusion ◽  
Diffusion Control ◽  
State Variables ◽  
Bifurcation Diagrams ◽  
Cell Parameters ◽  
Local Activity ◽  
Nonlinear Network

This paper presents some analytical criteria for local activity principle in reaction–diffusion Cellular Nonlinear Network (CNN) cells [Chua, 1997, 1999] that have four local state variables with three ports. As a first application, a cellular nonlinear network model of tumor growth and immune surveillance against cancer (GISAC) is discussed, which has cells defined by the Lefever–Erneaux equations, representing the densities of alive and dead cancer cells, as well as the number of free and bound cytotoxic cells, per unit volume. Bifurcation diagrams of the GISAC CNN provide possible explanations for the mechanism of cancer diffusion, control, and elimination. Numerical simulations show that oscillatory patterns and convergent patterns (representing cancer diffusion and elimination, respectively) may emerge if selected cell parameters are located nearby or on the edge of the chaos domain. As a second application, a smoothed Chua's oscillator circuit (SCC) CNN with three ports is studied, for which the original prototype was introduced by Chua as a dual-layer two-dimensional reaction–diffusion CNN with three state variables and two ports. Bifurcation diagrams of the SCC CNN are computed, which only demonstrate active unstable domains and edges of chaos. Numerical simulations show that evolution of patterns of the state variables of the SCC CNN can exhibit divergence, periodicity, and chaos; and the second and the fourth state variables of the SCC CNNs may exhibit generalized synchronization. These results demonstrate once again Chua's assertion that a wide spectrum of complex behaviors may exist if the corresponding CNN cell parameters are chosen in or nearby the edge of chaos.

Surface reactions observed by photoemission electron microscopy (PEEM)

1992 ◽  
Vol 50 (1) ◽  
pp. 286-287
Author(s):  
H.H. Rotermund
Keyword(s):  
Electron Microscopy ◽  
Electron Microscope ◽  
Work Function ◽  
Chemical Reactions ◽  
Reaction Diffusion ◽  
Dynamic Processes ◽  
Clean Surface ◽  
Crystal Surfaces ◽  
Single Crystal Surfaces ◽  
Photoemission Electron

Chemical reactions at a surface will in most cases show a measurable influence on the work function of the clean surface. This change of the work function δφ can be used to image the local distributions of the investigated reaction,.if one of the reacting partners is adsorbed at the surface in form of islands of sufficient size (Δ>0.2μm). These can than be visualized via a photoemission electron microscope (PEEM). Changes of φ as low as 2 meV give already a change in the total intensity of a PEEM picture. To achieve reasonable contrast for an image several 10 meV of δφ are needed. Dynamic processes as surface diffusion of CO or O on single crystal surfaces as well as reaction / diffusion fronts have been observed in real time and space.

The staining pattern of the tropomyosin sequence is displayed in a new paracrystal

1986 ◽  
Vol 44 ◽  
pp. 150-151
Author(s):  
M.K. Lamvik ◽  
L.L. Klatt
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Staining Pattern ◽  
Banding Patterns ◽  
Mass Thickness ◽  
New Form

Tropomyosin paracrystals have been used extensively as test specimens and magnification standards due to their clear periodic banding patterns. The paracrystal type discovered by Ohtsuki1 has been of particular interest as a test of unstained specimens because of alternating bands that differ by 50% in mass thickness. While producing specimens of this type, we came across a new paracrystal form. Since this new form displays aligned tropomyosin molecules without the overlaps that are characteristic of the Ohtsuki-type paracrystal, it presents a staining pattern that corresponds to the amino acid sequence of the molecule.

Electron probe x-ray microanalysis and electron microscopy of amino acid absorption and transport by the small intestine: inhibition by chemical poisons and correlation to the elemental composition of the epithelial cells

1986 ◽  
Vol 44 ◽  
pp. 134-135
Author(s):  
A. J. Tousimis
Keyword(s):  
Small Intestine ◽  
Amino Acid ◽  
Epithelial Cells ◽  
Elemental Composition ◽  
Isotope Labeling ◽  
Structural Components ◽  
X Ray ◽  
Human Small Intestine ◽  
Transport Studies

The elemental composition of amino acids is similar to that of the major structural components of the epithelial cells of the small intestine and other tissues. Therefore, their subcellular localization and concentration measurements are not possible by x-ray microanalysis. Radioactive isotope labeling: I131-tyrosine, Se75-methionine and S35-methionine have been successfully employed in numerous absorption and transport studies. The latter two have been utilized both in vitro and vivo, with similar results in the hamster and human small intestine. Non-radioactive Selenomethionine, since its absorption/transport behavior is assumed to be the same as that of Se75- methionine and S75-methionine could serve as a compound tracer for this amino acid.

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