A [3+2] Cycloaddition-1,2-Acyl Migration-Hydrolysis Cascade for Regioselective Synthesis of 1,2,3-Triazoles in Water

2021 ◽  
Author(s):  
Gargi Chakraborti ◽  
Tirtha Mandal ◽  
Charles Patriot Roy ◽  
Jyotirmayee Dash
Keyword(s):  
Reaction Kinetics ◽  
Acyl Migration ◽  
Aqueous Media ◽  
Regioselective Synthesis ◽  
Reaction Proceeds

A cascade sequence involving [3+2] cycloaddition, 1,2-acyl migration and hydrolysis produces 2H-1,2,3-triazoles via the regioselective formation of N2-carboxyalkylated triazoles. The reaction proceeds in aqueous media through an intriguing reaction kinetics...

scholarly journals DABCO Catalyzed Synthesis of Xanthene Derivatives in Aqueous Media

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Pradeep Paliwal ◽  
Srinivasa Rao Jetti ◽  
Anjna Bhatewara ◽  
Tanuja Kadre ◽  
Shubha Jain
Keyword(s):  
Reaction Time ◽  
Aqueous Media ◽  
Environmentally Friendly ◽  
The Other ◽  
Short Reaction Time ◽  
Xanthene Derivatives ◽  
Reaction Proceeds ◽  
Conventional Methods

The reaction of 5,5-dimethylcyclohexane-1,3-dione with various heteroarylaldehydes afforded the corresponding heteroaryl substituted xanthene derivatives 1(a–f). The reaction proceeds via the initial Knoevenagel, subsequent Michael, and final heterocyclization reactions using 1,4-diazabicyclo[2.2.2]octane (DABCO) as a catalyst in aqueous media. The synthesized heteroaryl substituted xanthenes 1(a–f) reacted with malononitrile to obtain different alkylidenes 2(a–f). Short reaction time, environmentally friendly procedure, avoiding of cumbersome apparatus, and excellent yields are the main advantages of this procedure which makes it more economic than the other conventional methods.

Synthesis of 2,3-Dihydrotryptamines from Amide Solvents and Acyclic Materials through Metal-Free Amidoalkylarylation of Unactivated Alkenes

Synlett ◽  
2019 ◽  
Vol 30 (11) ◽  
pp. 1329-1333
Author(s):  
Yubin Ji ◽  
Siping Yang ◽  
Shiyi Lin ◽  
Yan Wang ◽  
Chenfeng Ji ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Metal Free ◽  
Simple Operation ◽  
Reaction Proceeds

The first synthesis of 2,3-dihydrotryptamines from acyclic materials and an exo-selective amidoalkylation/cyclization cascade of N-allyl anilines through α-C(sp3)–H functionalization of simple amides across unactivated alkenes are presented. This reaction proceeds in mixed aqueous media and under metal-free conditions and features a broad substrate scope and a simple operation.

Iridium-catalyzed orthogonal and regioselective synthesis of triazole disulfides in aqueous media under mild conditions

2020 ◽  
Vol 22 (8) ◽  
pp. 2394-2398 ◽  
Author(s):  
Ming Li ◽  
Nan Zheng ◽  
Junhao Li ◽  
Yubin Zheng ◽  
Wangze Song
Keyword(s):  
Aqueous Media ◽  
Regioselective Synthesis ◽  
Biological Media ◽  
Mild Conditions ◽  
Catalyzed Reactions

Triazole disulfides were prepared in water or biological media under mild conditions by orthogonal and regioselective Ir-catalyzed reactions.

Curium(III) Radiation-Induced Reaction Kinetics in Aqueous Media

2021 ◽  
Author(s):  
Gregory Peter Horne ◽  
Travis Grimes ◽  
Peter Zalupski ◽  
David Meeker ◽  
Thomas Albrecht-Schoenzart ◽  
...  
Keyword(s):  
Reaction Kinetics ◽  
Aqueous Media ◽  
Solution Chemistry ◽  
Radiation Induced ◽  
Insight Into ◽  
Induced Reaction

Insight into the effects of radiolytic processes on the actinides is critical for advancing our understanding of their solution chemistry because the behaviour of these elements cannot be easily separated...

Gold-catalyzed intramolecular hydroamination of terminal alkynes in aqueous media: efficient and regioselective synthesis of indole-1-carboxamides

2009 ◽  
Vol 11 (8) ◽  
pp. 1201 ◽  
Author(s):  
Deju Ye ◽  
Jinfang Wang ◽  
Xu Zhang ◽  
Yu Zhou ◽  
Xiao Ding ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Regioselective Synthesis ◽  
Terminal Alkynes

ChemInform Abstract: Gold-Catalyzed Intramolecular Hydroamination of Terminal Alkynes in Aqueous Media: Efficient and Regioselective Synthesis of Indole-1-carboxamides.

ChemInform ◽  
2009 ◽  
Vol 40 (52) ◽  
Author(s):  
Deju Ye ◽  
Jinfang Wang ◽  
Xu Zhang ◽  
Yu Zhou ◽  
Xiao Ding ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Regioselective Synthesis ◽  
Terminal Alkynes

Organometallic reactions in aqueous media — Antimony-mediated allylation of carbonyl compounds and the nature of allylstibine intermediates

2001 ◽  
Vol 79 (11) ◽  
pp. 1536-1540
Author(s):  
Lian-Hai Li ◽  
Tak Hang Chan
Keyword(s):  
Carbonyl Compounds ◽  
Good Yield ◽  
Allyl Bromide ◽  
Aqueous Media ◽  
Organometallic Reactions ◽  
Homoallylic Alcohols ◽  
Reaction Proceeds

Commercial antimony metal, in aqueous 1 M H(D)Cl solution, reacts with allyl bromide and aldehydes to give the corresponding homoallylic alcohols in good yield. The reaction proceeds through the formation of allylstibine intermediates. The structures of the allylstibine intermediates are likely to be allylstibine dibromide and diallylstibine bromide.Key words: allylation reaction, aqueous organometallic reactions, homoallylic alcohols, allylstibine dibromide, diallylstibine bromide.

ChemInform Abstract: Silver-Catalyzed Intramolecular Hydroamination of Alkynes in Aqueous Media: Efficient and Regioselective Synthesis for Fused Benzimidazoles.

ChemInform ◽  
2011 ◽  
Vol 42 (27) ◽  
pp. no-no
Author(s):  
Xu Zhang ◽  
Yu Zhou ◽  
Hengshuai Wang ◽  
Diliang Guo ◽  
Deju Ye ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Regioselective Synthesis

ChemInform Abstract: Metal Free ipso Iodination of Arylboronic Acids Using CTAB/I2in Aqueous Media: Green and Regioselective Synthesis of Aryliodides under Mild Conditions.

ChemInform ◽  
2015 ◽  
Vol 46 (35) ◽  
pp. no-no
Author(s):  
Rajesh H. Tale ◽  
Gopal K. Toradmal ◽  
Venkatesh B. Gopula ◽  
Atish H. Rodge ◽  
Rajendra P. Pawar ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Regioselective Synthesis ◽  
Metal Free ◽  
Arylboronic Acids ◽  
Mild Conditions
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