scholarly journals Taming the Reactivity of Alkyl Azides by Intramolecular Hydrogen Bonding: Site-Selective Conjugation of Unhindered Diazides

2021 ◽  
Author(s):  
Koshiro Maegawa ◽  
Hiroki Tanimoto ◽  
Seiji Onishi ◽  
Takenori Tomohiro ◽  
Tsumoru Morimoto ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Click Chemistry ◽  
Intramolecular Hydrogen Bonding ◽  
Alkyl Azides ◽  
Organic Azides ◽  
Intramolecular Hydrogen ◽  
Site Selective ◽  
Hydrogen Bonding Site ◽  
Bonding Site

Organic azides are still in the center of click chemistry connecting two molecules. However, taming the conjugation selectivity of azides is difficult without the help of the bulky groups. We...

scholarly journals Site-selective nitrenoid insertions utilizing postfunctionalized bifunctional rhodium(ii) catalysts

2019 ◽  
Vol 10 (11) ◽  
pp. 3324-3329 ◽  
Author(s):  
Jan-Philipp Berndt ◽  
Yevhenii Radchenko ◽  
Jonathan Becker ◽  
Christian Logemann ◽  
Dhaka R. Bhandari ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Site Selective ◽  
Hydrogen Bonding Site ◽  
Bonding Site

Site-selective nitrenoid insertions are made possible with a postfunctionalized dirhodium(ii)-catalyst equipped with a remote hydrogen bonding site.

scholarly journals Site-selective Intramolecular Hydrogen-Bonding Interactions in Phosphorylated Serine and Threonine Dipeptides

2008 ◽  
Vol 112 (51) ◽  
pp. 16782-16787 ◽  
Author(s):  
Kyung-Koo Lee ◽  
Eunmyung Kim ◽  
Cheonik Joo ◽  
Jaewook Song ◽  
Hogyu Han ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Intramolecular Hydrogen Bonding ◽  
Hydrogen Bonding Interactions ◽  
Intramolecular Hydrogen ◽  
Site Selective

scholarly journals Site-selective Intramolecular Hydrogen-Bonding Interactions in Phosphorylated Serine and Threonine Dipeptides

2009 ◽  
Vol 113 (11) ◽  
pp. 3590-3590
Author(s):  
Kyung-Koo Lee ◽  
Eunmyung Kim ◽  
Cheonik Joo ◽  
Jaewook Song ◽  
Hogyu Han ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Intramolecular Hydrogen Bonding ◽  
Hydrogen Bonding Interactions ◽  
Intramolecular Hydrogen ◽  
Site Selective

scholarly journals Star Poly(N-isopropylacrylamide) Tethered to Polyhedral Oligomeric Silsesquioxane (POSS) Nanoparticles by a Combination of ATRP and Click Chemistry

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Shiao-Wei Kuo ◽  
Jing-Long Hong ◽  
Yu-Chan Huang ◽  
Jem-Kun Chen ◽  
Shih-Kang Fan ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Click Chemistry ◽  
Polyhedral Oligomeric Silsesquioxane ◽  
Star Polymers ◽  
Intramolecular Hydrogen Bonding ◽  
Solution Temperature ◽  
Critical Solution Temperature ◽  
Intramolecular Hydrogen ◽  
Oligomeric Silsesquioxane ◽  
Blue Photoluminescence

New star poly(N-isopropylacrylamide)-b-polyhedral oligomeric silsesquioxane (PNIPAm-b-POSS) copolymers were synthesized from octa-azido functionalized POSS (N3-POSS) and alkyne-PNIPAm, which was prepared using an alkyne-functionalized atom transfer radical polymerization (ATRP) initiator (propargyl 2-bromo-2-methylpropionamide), via click chemistry. These star PNIPAm-b-POSS copolymers undergo a sharp coil-globule transition in water at above 32°C changing from a hydrophilic state below this temperature to a hydrophobic state above it, which is similar to linear PNIPAm homopolymers. More interestingly, we found that these star polymers exhibited strong blue photoluminescence in water above a lower critical solution temperature (LCST). This photoluminescence was likely due to the constrained geometric freedom and relatively rigid structure caused by intramolecular hydrogen bonding within the star PNIPAm polymers, which exhibit an intrinsic fluorescent behavior.

Theoretical study of intramolecular hydrogen bonding and molecular geometry of 2-trifluoromethylphenol

10.1002/jcc.2 ◽  
1996 ◽  
Vol 17 (16) ◽  
pp. 1804-1819 ◽  
Author(s):  
Attila Kov�cs ◽  
Istv�n Kolossv�ry ◽  
G�bor I. Csonka ◽  
Istv�n Hargittai
Keyword(s):  
Hydrogen Bonding ◽  
Theoretical Study ◽  
Molecular Geometry ◽  
Intramolecular Hydrogen Bonding ◽  
Intramolecular Hydrogen

Intramolecular Hydrogen Bonding Facilitates Electrocatalytic Reduction of Nitrite in Aqueous Solutions

2019 ◽  
Vol 58 (14) ◽  
pp. 9443-9451 ◽  
Author(s):  
Song Xu ◽  
Hyuk-Yong Kwon ◽  
Daniel C. Ashley ◽  
Chun-Hsing Chen ◽  
Elena Jakubikova ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Aqueous Solutions ◽  
Intramolecular Hydrogen Bonding ◽  
Electrocatalytic Reduction ◽  
Intramolecular Hydrogen

Seven-Membered Intramolecular Hydrogen Bonding of Phenols: Database Analysis and Phloroglucinol Model Compounds

2012 ◽  
Vol 2012 (24) ◽  
pp. 4483-4492 ◽  
Author(s):  
Ronald K. Castellano ◽  
Yan Li ◽  
Edwin A. Homan ◽  
Andrew J. Lampkins ◽  
Iris V. Marín ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Intramolecular Hydrogen Bonding ◽  
Model Compounds ◽  
Database Analysis ◽  
Intramolecular Hydrogen

scholarly journals NMR of Natural Products as Potential Drugs

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3763
Author(s):  
Poul Erik Hansen
Keyword(s):  
Natural Products ◽  
Hydrogen Bonding ◽  
Density Functional ◽  
Chemical Shifts ◽  
Isotope Effects ◽  
Density Functional Theory Calculations ◽  
Intramolecular Hydrogen Bonding ◽  
Chemical Equilibria ◽  
Nmr Techniques ◽  
Intramolecular Hydrogen

This review outlines methods to investigate the structure of natural products with emphasis on intramolecular hydrogen bonding, tautomerism and ionic structures using NMR techniques. The focus is on 1H chemical shifts, isotope effects on chemical shifts and diffusion ordered spectroscopy. In addition, density functional theory calculations are performed to support NMR results. The review demonstrates how hydrogen bonding may lead to specific structures and how chemical equilibria, as well as tautomeric equilibria and ionic structures, can be detected. All these features are important for biological activity and a prerequisite for correct docking experiments and future use as drugs.

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