Organocatalytic asymmetric synthesis of multifunctionalized α-carboline-spirooxindole hybrids that suppressed proliferation in colorectal cancer cells

Author(s):  
Xiang-Hong He ◽  
Xue-Ju Fu ◽  
Gu Zhan ◽  
Nan Zhang ◽  
Xiang Li ◽  
...  

Organocatalytic asymmetric [3 + 3] annulations of isatin-derived MBH carbonates and indolin-2-imines have been efficiently achieved. This appears to be the first enantioselective approach to use isatin-derived MBH carbonates as...

2019 ◽  
Author(s):  
Qi Zhang ◽  
Qi Qi ◽  
Xuemeng Qian ◽  
Jiajing Cai ◽  
Xing Shen ◽  
...  

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