scholarly journals Unexpected Formation of 1,2- and 1,4-Bismethoxyl Sc3N@Ih-C80 Derivatives via Regioselective Anion Addition: Unambiguous Structural Identification and Mechanism Study

2021 ◽  
Author(s):  
Yajing Hu ◽  
Yang-Rong Yao ◽  
Xuechen Liu ◽  
Ao Yu ◽  
Xiao-Ming Xie ◽  
...  
Keyword(s):  
Structural Identification ◽  
Mechanism Study ◽  
Tetrabutylammonium Hydroxide ◽  
Unexpected Formation

An attempt to achieve heterocyclic cycloadducts of Sc3N@Ih-C80 via the reaction with Ph2C=O, PhC≡CPh or PhC≡N in the presence of tetrabutylammonium hydroxide (TBAOH) stored in CH3OH led to the formation...

scholarly journals Correction: Unexpected formation of 1,2- and 1,4-bismethoxyl Sc3N@Ih-C80 derivatives via regioselective anion addition: an unambiguous structural identification and mechanism study

2021 ◽  
Author(s):  
Yajing Hu ◽  
Yang-Rong Yao ◽  
Xuechen Liu ◽  
Ao Yu ◽  
Xiaoming Xie ◽  
...  
Keyword(s):  
Structural Identification ◽  
Mechanism Study ◽  
Unexpected Formation

Correction for ‘Unexpected formation of 1,2- and 1,4-bismethoxyl Sc3N@Ih-C80 derivatives via regioselective anion addition: an unambiguous structural identification and mechanism study’ by Yajing Hu et al., Chem. Sci., 2021, DOI: 10.1039/d1sc01178b.

STRUCTURAL IDENTIFICATION OF A THERMAL PROCESS USING THE VOLTERRA MODEL

2014 ◽  
Vol 45 (5) ◽  
pp. 471-484
Author(s):  
Safa Chouchane ◽  
Kais Bouzrara ◽  
Hassani Messaoud
Keyword(s):  
Thermal Process ◽  
Structural Identification ◽  
Volterra Model

Assemblies of D-peptides for Targeting Cell Nucleolus

2019 ◽  
Author(s):  
Huaimin Wang ◽  
Zhaoqianqi Feng ◽  
Weiyi Tan ◽  
Bing Xu
Keyword(s):  
Particle Morphology ◽  
Side Chain ◽  
Mechanism Study ◽  
Structural Analogue ◽  
Hydrophobic Residues ◽  
Subcellular Organelles ◽  
First Case ◽  
New Strategy ◽  
Peptide Derivative ◽  
Peptide Nanoparticles

<p>Selectively targeting cell nucleolus remains a challenge. Here we report the first case that D-peptides form membraneless molecular condensates with RNA for targeting cell nucleolus. A D-peptide derivative, enriched with lysine and hydrophobic residues, self-assembles to form nanoparticles, which enter cells through clathrin dependent endocytosis and mainly accumulate at cell nucleolus. Structural analogue of the D-peptide reveals that particle morphology of the assemblies, which depends on the side chain modification, favors the cellular uptake. Contrasting to those of the D-peptide, the assemblies of the corresponding L-enantiomer largely localize in cell lysosomes. Preliminary mechanism study suggests that the D-peptide nanoparticles interact with RNA to form membraneless condensates in the nucleolus, which further induces DNA damage and results in cell death. This work illustrates a new strategy for rationally designing supramolecular assemblies of D-peptides for targeting subcellular organelles.</p>

Sign in / Sign up

Export Citation Format

Share Document